Beneficial Properties of Tea on Human Health: A Mini Review

Pradhan, Surbhi; Dubey, R. C.

doi:10.21276/irjps.2019.6.1.3

Cited by 3 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tea contains many polyphenolic components like epicatechin (EC), epicatechin-3-gallate (ECG), epigallocatechin (EGC) and epigallocatechin-3-gallate (EGCG). These polyphenols may have antioxidant, anti-inflammatory, anti-carcinogenic and antimicrobial properties in numerous humans, animals either whole or in vitro studies ( Alschuler, 1998 , Pradhan and Dubey, 2019 ). Green tea contains other compounds such as flavanols, glycosides, chlorogenic acid, carotenoids, quinic acids, trigalloylglucose, protein, lignin, chlorophyll, minerals (aluminum or manganese, depending on the soil content), caffeine and methylxanthines ( Wang et al, 2013 , Baláži et al, 2016 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of prenatal exposure of green tea extract on the developing central nervous system of rat fetuses; histological, immune-histochemical and ultrastructural studies

El–Borm

El-Gaber

2021

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

Although, several health benefits were associated with green tea, these effects may be beneficial up to a certain dose. Higher doses of green tea may cause several adverse effects. So, there is a need to test the potential negative effects of green tea during pregnancy. This study was designated to evaluate the effect of prenatal exposure of green tea extract on the development of the central nervous system of 20-day old rat fetuses. The pregnant rats were divided into 4 groups; the control group (received distal water) and the other 3 groups received green tea extract at different doses (200, 600 & 1000 mg/kg/day, respectively) from the 6th to 15th day of gestation i.e., during the organogenesis phase of development. Cerebral cortex, cerebellum and spinal cord specimens were subjected to histological, immunohistochemical and ultrastructure investigations. The body weight of both mothers and fetuses was significantly decreased in the groups that received 600 and 1000 mg green tea extract. Also, the neuronal tissues displayed various signs of degeneration which were evident with the 600 and 1000 mg doses. Green tea extract also increases the glial fibrillary acidic protein (GFAP) and decreases the proliferating cell nuclear antigen (PCNA) which were directly proportional with increasing the dose. Administration of green tea extract during rat organogenesis period induced various histological, immunohistochemical and ultrastructural degenerative changes in the cerebral cortex, cerebellum and spinal cord of 20-day old rat fetuses. These deleterious changes were directly proportional to increasing the green tea extract dose. Thus, it should be stressed that the effect of green tea is dose-dependent and therefore it can be either beneficial or adverse.

show abstract

Section: Introductionmentioning

confidence: 99%