Biflavonoids from the moss Homalothecium lutescens

Preparative Isolation of six Anti‐Tumour Biflavonoids from Selaginella Doederleinii Hieron by High‐Speed Counter‐Current Chromatography

“…= 16.4,2.8 Hz,. The 1 H-NMR profiles of compound 3 matched with the reported NMR data for 2'' , 3''-dihydro-3' , 3'''-biapigenin (Seeger et al, 1993), which is the first time it has been discovered in S. doederleinii.…”

“…1 H‐NMR (DMSO‐ d 6, TMS) δ ppm: 7.86 (1H, d, J = 1.6 Hz, 2′‐H), 7.68 (1H, dd, J = 8.0, 1.6 Hz, 6′‐H), 7.48 (1H, d, J = 1.6 Hz, 2′′′‐H), 7.21 (1H,dd, J = 8.0, 1.6 Hz, 6′′′‐H), 6.67 (1H, d, J = 8.0 Hz, 5′‐H), 6.63 (1H, s, 3‐H), 6.57 (1H, d, J = 8.0 Hz, 5′′′‐H), 6.45 (1H, d, J = 1.6 Hz, 8‐H), 6.11(1H, d, J = 1.6 Hz, 6‐H ), 5.87 (1H, d, J = 1.6 Hz, 8′′‐H), 5.81 (1H, d, J = 1.6 Hz, 6′′‐H), 5.50 (1H, dd, J = 2.8, 2.8 Hz, 2′′‐H), 2.75 (1H, dd, J = 16.4, 2.8 Hz, 3′′‐H). The 1 H‐NMR profiles of compound 3 matched with the reported NMR data for 2'', 3''‐dihydro‐3', 3'''‐biapigenin (Seeger et al ., ), which is the first time it has been discovered in S . doederleinii .…”

Ring-B Linked Bidihydroflavonoids fromThuidium kanedae Sak

“…The known compounds were determined as 3',3'''-binaringenin (2), 3 pentadecane (3), 4 methyl β-orcinolarboxylate (4), 5 β-sitosterol (5) 6 and daucostenol (6) 6 , respectively, from their MS and 1 H NMR spectra, which were identical to the reported data.…”

“…This paper reports the isolation and identification of a new biflavonoid, thuidinin 1, together with 5 known compounds 2-6. Their structures were elucidated as 4',4''',5",7,7"-pentahydroxy-5-methoxy-3',3'''-biflavanone (1), 3',3'''-binaringenin (2), 3 pentadecane (3), 4 methyl β-orcinolarboxylate (4), 5 β-sitosterol (5) 6 and daucostenol (6) 6 based on extensive spectroscopic data analyses and comparisons with those in literatures. To the best of our knowledge, compound 1 is a new compound.…”

Pharmacokinetics, Tissue Distribution and Protein Binding Studies of Chrysocauloflavone I in Rats

“…The interflavonoidal linkage of most biflavones discovered in herbs are between C and C of two flavonoid subunits, such as amentoflavone [13], robustaflavone [14], heveaflavone [15], 3′′dihydro-3′,3′′′-biapigenin [16], 3′,3′′′-binaringenin [17], and 7,4′,7″,4″′-tetra-O-methyl-amentoflavone [18]. There are also a few natural biflavones, such as hinokiflavone [13], 2,3-dihydrohinokiflavone [19], and tetrahydrohinokiflavone [20], possessing the C(4′)-O-C(6′′) interflavonoidal linkage between two flavonoid subunits.…”