Bilateral transfer phenomenon: A functional magnetic resonance imaging pilot study of healthy subjects

Uggetti, Carla; Ausenda, Carlo D.; Squarza, Silvia; Cadioli, Marcello; Grimoldi, Ludovico; Cerri, C; Cariati, Maurizio

doi:10.1177/1971400916631992

Cited by 8 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This result is also consistent with previous transfer literature, where the cerebellum is one of the regions that is more frequently involved across studies (Jung et al, 2019;Lutz, Weidner, Shah, & Jancke, 2001;Matsumura et al, 2004;Obayashi, 2004;Parsons et al, 2005;Seidler & Noll, 2008;Shimizu, Wu, & Knowlton, 2016;Uggetti et al, 2016;Walz et al, 2015).…”

Section: Discussionsupporting

confidence: 93%

“…During the transfer test, the old models might be used directly (e.g., those related with the movements of the target, because such movements are equivalent in the training and the transfer phases) or to implement new ones that are useful in the new context, for example, to link the control of the eye and the hand (Miall & Jenkinson, ), which may be reflected in cerebellar activations. This result is also consistent with previous transfer literature, where the cerebellum is one of the regions that is more frequently involved across studies (Jung et al, ; Lutz, Weidner, Shah, & Jancke, ; Matsumura et al, ; Obayashi, ; Parsons et al, ; Seidler & Noll, ; Shimizu, Wu, & Knowlton, ; Uggetti et al, ; Walz et al, ).…”

Section: Discussionsupporting

confidence: 92%

“…On the other hand, despite the interest that motor transfer has aroused in behavioral research, there are few works on its neural correlates, which are still not well understood as several researchers have noted (Ruddy, Leemans, Woolley, Wenderoth, & Carson, 2017;Seidler & Noll, 2008;Uggetti et al, 2016). Therefore, it would be interesting to perform new studies to shed more light on this issue and allow further meta-analysis.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Neurofunctional correlates of eye to hand motor transfer

Modroño

Socas

Hernández‐Martín

et al. 2020

Human Brain Mapping

View full text Add to dashboard Cite

This work investigates the transfer of motor learning from the eye to the hand and its neural correlates by using functional magnetic resonance imaging (fMRI) and a sensorimotor task consisting of the continuous tracking of a virtual target. In pretraining evaluation, all the participants (experimental and control group) performed the tracking task inside an MRI scanner using their right hand and a joystick. After which, the experimental group practiced an eye‐controlled version of the task for 5 days using an eye tracking system outside the MRI environment. Post‐training evaluation was done 1 week after the first scanning session, where all the participants were scanned again while repeating the manual pretraining task. Behavioral results show that the training in the eye‐controlled task produced a better performance not only in the eye‐controlled modality (motor learning) but also in the hand‐controlled modality (motor transfer). Neural results indicate that eye to hand motor transfer is supported by the motor cortex, the basal ganglia and the cerebellum, which is consistent with previous research focused on other effectors. These results may be of interest in neurorehabilitation to activate the motor systems and help in the recovery of motor functions in stroke or movement disorder patients.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Neurofunctional correlates of eye to hand motor transfer

Modroño

Socas

Hernández‐Martín

et al. 2020

Human Brain Mapping

View full text Add to dashboard Cite

show abstract

“…Other researchers have demonstrated bilateral transfer using functional magnetic resonance imaging (fMRI). In 2016, Uggetti et al 49 investigated the association of specific brain activation patterns using fMRI with bilateral transfer while completing a nine hole peg test with nondominant hand and dominant hand training and found significant fMRI activation before and after training, particularly in movement control, coordination and working memory areas. In 2007, twenty-five participants were analyzed using fMRI while they performed a visuomotor adaption joystick task to position a cursor in a target circle, which appeared on a screen in one of four locations 50 .…”

Section: Discussionmentioning

confidence: 99%

Nondominant hand computer mouse training and the bilateral transfer effect to the dominant hand

Schweiger

Stone

Genschel

2021

Sci Rep

View full text Add to dashboard Cite

This study explored the effects of training computer mouse use in the nondominant hand on clicking performance of the dominant and nondominant hands. Computer mouse use is a daily operation in the workplace and requires minute hand and wrist movements developed and refined through practice and training for many years. Our study had eleven right-handed computer mouse users train their nondominant hand for 15 min a day, five days per week, for six weeks. This study found improved performance with the computer mouse in the dominant hand following nondominant hand training because of the bilateral transfer effect of training. Additionally, our study showed that the nondominant hand is capable of learning the complex movements that our dominant hand has trained for many years. Last, our research showed that nondominant hand performance decreases when the skill is not trained for over a year, but the performance is significantly higher than that prior to the original training and can be rapidly relearned. Overall, training the nondominant hand on the computer mouse will allow for improved performance in industry while allowing safer, sustainable, and more achievable work in a multitude of economies.

show abstract

“…A modified version of the Nine Hole Peg Test (mNHPT)-a quantitative test of upper extremity function [21]-was adopted to assess motor performance. Previous studies have shown that the performance of the standard NHPT strongly depends on frontoparietal network functioning [22] [23]. Moreover, NHPT performance improves with repetition over time [24], denoting the test's suitability as a motor learning endpoint.…”

Section: Motor Trainingmentioning

confidence: 99%

The value of corticospinal excitability and intracortical inhibition in predicting motor skill improvement driven by action observation

Nuara

Bazzini

Cardellicchio

et al. 2021

Preprint

View full text Add to dashboard Cite

BACKGROUND AND OBJECTIVE: Action observation can sustain motor skill improvement. At the neurophysiological level, action observation affects the excitability of the motor cortices, as measured by transcranial magnetic stimulation. However, whether the cortical modulations induced by action observation may explain the amount of motor improvement driven by action observation training (AOT) remains to be addressed. METHODS: We conducted a two-phase study involving 40 volunteers. First, we assessed the effect of action observation on corticospinal excitability (amplitude of motor evoked potentials), short-interval intracortical inhibition, and transcallosal inhibition (ipsilateral silent period). Subsequently, a randomized-controlled design was applied, with AOT participants asked to observe and then execute, as quickly as possible, a right-hand dexterity task six consecutive times, whereas controls had to observe a no-action video before performing the same task. RESULTS: AOT participants showed greater performance improvement relative to controls. The amount of improvement in the AOT group was predicted by the amplitude of corticospinal modulation during action observation and even more by the amount of intracortical inhibition induced by action observation. Importantly, these relations were found specifically for the AOT group and not for the controls. CONCLUSIONS: In this study, we identified the neurophysiological signatures associated with, and potentially sustaining, the outcome of AOT. Intracortical inhibition driven by action observation plays a major role. These findings elucidate the cortical mechanisms underlying AOT efficacy and open to predictive assessments for the identification of potential responders to AOT, informing the rehabilitative treatment individualization.

show abstract

Bilateral transfer phenomenon: A functional magnetic resonance imaging pilot study of healthy subjects

Abstract: Our study shows, in a small group of healthy subjects, the modification of the fMRI activation pathway of a motor task performed by the non-dominant hand after intensive exercise performing the same task with the dominant hand.

Cited by 8 publications

References 14 publications

Neurofunctional correlates of eye to hand motor transfer

Neurofunctional correlates of eye to hand motor transfer

Nondominant hand computer mouse training and the bilateral transfer effect to the dominant hand

The value of corticospinal excitability and intracortical inhibition in predicting motor skill improvement driven by action observation

Contact Info

Product

Resources

About