Biliary Complications After 52 Adult Living Donor Liver Transplantations: A Single-Center Experience

Iwamoto, Hitoshi; Hama, K.; Nakamura, Yuki; Katoh, Osamu; Yokoyama, T.; Kihara, Y.; Ashizawa, T.; Niido, Teitetsu; Matsuno, Naoto; Nagao, Toshiyasu

doi:10.1016/j.transproceed.2008.07.042

Cited by 11 publications

(9 citation statements)

References 4 publications

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“…In the present study, the incidence of overall biliary complications following liver transplantation was 36%; anastomotic biliary structure (15%) was the most common biliary complication, followed by biliary leakage (10%). These results are consistent with previous reports (1,4,5,19). A systematic review comprised 61 published papers, demonstrating that the overall incidence of biliary stricture and leakage was 13% and 8% (5).…”

Section: Discussionsupporting

confidence: 93%

Endoscopic treatment of biliary complications following liver transplantation

Seven¹,

Çınar²,

İdilman³

et al. 2014

Turk J Gastroenterol

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Section: Discussionsupporting

confidence: 93%

Endoscopic treatment of biliary complications following liver transplantation

Seven¹,

Çınar²,

İdilman³

et al. 2014

Turk J Gastroenterol

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“…The 14 [1], [2], [8], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24] studies were published from 1990 to 2009. The characteristics are presented in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Recipient Outcomes after ABO-Incompatible Liver Transplantation: A Systematic Review and Meta-Analysis

et al. 2011

PLoS ONE

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BackgroundABO-incompatible live transplantation (ILT) is not occasionally performed due to a relative high risk of graft failure. Knowledge of both graft and patient survival rate after ILT is essential for donor selection and therapeutic strategy. We systematically reviewed studies containing outcomes after ILT compared to that after ABO-compatible liver transplantation (CLT).Methodology/Principal FindingsWe carried out a comprehensive search strategy on MEDLINE (1966–July 2010), EMBASE (1980–July 2010), Biosis Preview (1969–July 2010), Science Citation Index (1981–July 2010), Cochrane Database of Systematic Reviews (Cochrane Library, issue 7, 2010) and the National Institute of Health (July 2010). Two reviewers independently assessed the quality of each study and abstracted outcome data. Fourteen eligible studies were included which came from various medical centers all over the world. Meta-analysis results showed that no significantly statistical difference was found in pediatric graft survival rate, pediatric and adult patient survival rate between ILT and CLT group. In adult subgroup, the graft survival rate after ILT was significantly lower than that after CLT. The value of totally pooled OR was 0.64 (0.55, 0.74), 0.92 (0.62, 1.38) for graft survival rate and patient survival rate respectively. The whole complication incidence (including acute rejection and biliary complication) after ILT was higher than that after CLT, as the value of totally pooled OR was 3.02 (1.33, 6.85). Similarly, in acute rejection subgroup, the value of OR was 2.02 (1.01, 4.02). However, it was 4.08 (0.90, 18.51) in biliary complication subgroup.Conclusions/SignificanceIn our view, pediatric ILT has not been a contraindication anymore due to a similar graft and patient survival rate between ILT and CLT group. Though adult graft survival rate is not so satisfactory, ILT is undoubtedly life-saving under exigent condition. Most studies included in our analysis are observational researches. Larger scale of researches and Randomized-Control Studies are still needed.

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“…While biliary leakage can often be seen in an early postsurgical state [9,10], biliary strictures are more frequently found several months to years after liver transplantation [11]. Clinical symptoms include abnormal laboratory parameters indicating cholestasis, but the clinical presentation can also be inconspicuous.…”

Section: Discussionmentioning

confidence: 99%