Bimetal-organic framework/GOx-based hydrogel dressings with antibacterial and inflammatory modulation for wound healing

A pH-responsive ZC-QPP hydrogel for synergistic antibacterial and antioxidant treatment to enhance wound healing

“…Appropriate inflammation exerts an antibacterial effect during wound healing, but excessive inflammation can lead to high oxidative stress that damages normal cells. 31,32 Antioxidants help to capture and neutralize free radicals, thus eliminating their damage to the body. 33 Due to Ce 3+ /Ce 4+ coexistence properties of CeO 2 NPs, they can regulate the redox state of cells through redox cycling reactions between Ce 3+ and Ce 4+ , enabling them to play an important role as oxidative and antioxidant agents in antibacterial, anti-inflammatory and anticancer therapy.…”

Effective antibacterial action of a 2D bimetallic Al/Fe-TCPP NMOF loaded with glucose oxidase by a cascade catalytic reaction and depleting glutathione simultaneously

“…S5, ESI†). 30 Meanwhile, the ζ potential of Al/Fe-TCPP NMOF/GO x changed from +10.3 mV to −8.2 mV, indicating that GO x has successfully adsorbed on the Al/Fe-TCPP NMOF (Fig. 1g).…”

Smart microneedle patches for wound healing and management

“…An excessive or prolonged inflammatory response can cause an undesired polarization of immune cells and lead to wound deterioration. 182 Therefore, the development of dressings with inflammation modulating ability is of great importance to promote wound healing. Macrophages are key players in the wound healing process and serve as important targets for wound healing.…”