Binary Mixtures of Colloidal Cellulose Nanocrystals and Laponite for Preparation of Functional Nanocomposites

Abstract

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Nanorod/nanodisk‐integrated liquid crystalline systems for starvation, chemodynamic, and photothermal therapy of cancer

“…30 The LAP group had 001 Bragg reflections, and the CNC/LAP group also exhibited an attenuated CNC pattern and the presence of LAP peaks. 30 The thermal properties of the fabricated CNC/LAP constructs were investigated using TGA (Figure 2d). In the CNC group, a weight loss of 5.1% was detected in the range of 30-100 C, which can be attributed to the effect of the evaporation of water and volatile substances.…”

“…60 The flat profile in the low-Q region indicates the form factor originating from the nanorod shape of the CNC. 30 Furthermore, the interactions between CNC and LAP were investigated using the WAXS analysis (Figure S3). The CNC group exhibited three major peaks at 1.06, 1.16, and 1.60 Å À1 , corresponding to the (110), (110), and (200) planes of cellulose I β .…”

“…30 Blue and red indicate the directions perpendicular and parallel to the slow axis of the λ-plate in the nematic region, respectively. 30 The birefringent feature, probably owing to the nematic phase, seemed to appear in the CNC/LAP group, considering its concentration ratio. 30 Furthermore, in the case of the CNC/ICG/GOx/ Cu/LAP group (Figure S4), an optical feature indicating the nematic phase of CNC/LAP was observed.…”

“…Although the face of the LAP disk possesses a net negative charge, its edge exhibits a charge that is either positive or less negative than the face, depending on the adjacent pH 29 . Thus, the combination of these two materials (CNC and LAP) can provide ideal characteristics for rheologically tuned hydrogel systems 30 . A complex CNC/LAP network can be prepared based on electrostatic interactions and hydrogen bonding between the hydroxyl groups on the outer surfaces of these materials 30 .…”

“…30 A complex CNC/LAP network can be prepared based on electrostatic interactions and hydrogen bonding between the hydroxyl groups on the outer surfaces of these materials. 30 Electrostatic interactions between the positively charged edges of LAP and negatively charged CNC can be induced, as shown in other examples of LAP/cellulose nanofibers and LAP/alginate. 31,32 However, although a binary mixture of CNC and LAP aimed at dye absorption was reported, 30 it has never been practically applied to drug delivery systems.…”