Bio-hybridization of nanobactericides with cellulose films for effective treatment against members of ESKAPE multi-drug-resistant pathogens

Antibacterial and Antimycotic Activity of Epilobium angustifolium L. Extracts: A Review

“…The gathered literature also includes the assessment of antimicrobial activity of hydrogels containing fireweed extracts [57][58][59][60][61][62][63][64][65][66][67][68][69][70][71][72][73] and bactericides with silver nanoparticles [55]. Extracts were prepared from different parts of plants: roots [57,62], leaves [56,60,64,[74][75][76], flowering aerial parts [13,60,[68][69][70]73,76], flowers [60,64,72], aerial parts or herb [55,58,59,65,71], the whole plant [63], and seeds [61]. In some articles [66,67,74], the plant parts were not specified.…”

“…E. angustifolium extracts were prepared in different ways, e.g., using a shaker incubator and evaporator [72], by maceration of plant material with solvent and centrifugation [60], by evaporation and lyophilization [65], or by ultrasonication of infusion and lyophilization [56]. Phytochemical characterization of tested extracts was included in some articles [13,55,56,[67][68][69][70][71][73][74][75][76], but it was usually limited to the total content of polyphenols and/or the total content of flavonoids and tannins. Strong antibacterial effect against MRSA.…”

“…The biological activity of the essential oil of E. angustifolium has not been thoroughly studied, but antioxidant, antibacterial, and antimycotic properties have been documented [50][51][52]. Other groups of active metabolites such as alkaloids (angustifoline A), lignans, fatty acids (tricosanoic, nervonic, linoleic, palmitic, caprylic, caproic, butyric, and others), and sterols (campesterol, stigmasterol, β-sitosterol, cholesterol, and their derivatives) have also been identified [13,53,54] To date, E. angustifolium extracts have been tested in the treatment of BPH, in wound healing or as ingredients of cosmetic products, nano-bactericides [55], and as a food preservative [56]. Antimicrobial properties of fireweed have been studied since the beginning of this century, but in the last decade, the number of publications has increased significantly.…”

Bio-nanobactericides: an emanating class of nanoparticles towards combating multi-drug resistant pathogens

“…These capped layer across the nanoparticles are often considered to be important factor to obtain desired biological activity [6]. The functional groups associated with capping agents helps in tailoring or engineering the functional properties to the nanoparticles [7,9,37]. These biomimetic approach has driven great potential towards mastering technical advances in nanobactericides production by meeting the substantial challenges [38].…”

“…Different classes of nanobactericides are employed as effective agent to suppress or eradicate the microbial infections [8,9]. Nanobactericides are reported to interfere with the normal metabolic process of pathogens by destroying or inactivating the vital components required for normal cellular activities [10].…”