2010
DOI: 10.1002/pola.23884
|View full text |Cite
|
Sign up to set email alerts
|

Bio‐safe synthesis of linear and branched PLLA

Abstract: The catalytic activities of Bi(III) acetate (Bi(OAc) 3 ) and of creatinine towards the ring-opening polymerization of Llactide have been compared with those of a stannous (II) ethylhexanoate ((SnOct) 2 )-based system and with those of a system catalyzed by enzymes. All four were suitable catalysts for the synthesis of high and moderate molecular weight poly(L-lactide)s and the differences in reactivity and efficiency have been studied. Linear and branched poly(L-lactide)s were synthesized using these bio-safe … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
5

Citation Types

0
19
0

Year Published

2011
2011
2016
2016

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 21 publications
(20 citation statements)
references
References 32 publications
0
19
0
Order By: Relevance
“…ROP of lactide can be catalyzed by the addition of organometallic compounds such as stannous octanoate [1][2][3] and zinc lactate 4 and high temperatures have to be applied. Such conditions induce side reactions such as transesterification and racemization, which hamper the control over the polymerization process.…”
Section: Introductionmentioning
confidence: 99%
“…ROP of lactide can be catalyzed by the addition of organometallic compounds such as stannous octanoate [1][2][3] and zinc lactate 4 and high temperatures have to be applied. Such conditions induce side reactions such as transesterification and racemization, which hamper the control over the polymerization process.…”
Section: Introductionmentioning
confidence: 99%
“…One interesting aspect of the lactide ring‐opening reaction is the flexibility in designing different molecular architectures by employing multifunctional initiators. Different branched structures such as star‐shaped with arm numbers from 3 to 6, dendrimers, comb‐like, and barbell‐like molecules are synthesized by applying this strategy. An alternative procedure for the in situ synthesis of branched PLA is to use co‐monomers bearing initiation groups, such as 2,2‐ bis (hydroxymethyl) butyric acid in the presence of a tertiary amine, glycidol, and 5‐hydroxymethyl‐1,4‐dioxane‐2‐one .…”
Section: Introductionmentioning
confidence: 99%
“…Among the metal salts and coordination compounds studied for the ROP of LA, also titanium‐based systems have been considered. Following the pioneering work of Kricheldorf et al9 on the use of titanium alkoxides as initiators of the polymerization of lactones, several types of Ti‐based complexes have been studied for the ROP of LA to produce PLA 10–25. Indeed, some of the above systems enable stereoselective polymerization reactions.…”
Section: Introductionmentioning
confidence: 99%