Bioactive compounds content and total antioxidant activity of two savoy cabbages

Fernández-León, A.M.; Lozano, M.; González, David; Ayuso, M.C.; Fernández-León, M.F.

doi:10.17221/76/2014-cjfs

Cited by 15 publications

(9 citation statements)

References 27 publications

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“…Among the various phytoconstituents, flavonoids and phenolic compounds have beneficial effects in the oxidative stress-induced inflammatory condition. Flavonoids are particularly reported for significant antioxidant, vasculoprotector, antihepatotoxic, antiallergic, anti-inflammatory and antitumor activity [19]. Our data confirmed that EA fractions of methanolic extracts of L. globosus exhibited potential antioxidant and free radical scavenging capacity (Figure 1) due to the presence of flavonoids and phenolic compounds (Table 1).…”

Section: Discussionsupporting

confidence: 81%

Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice

Rana¹,

Khatun²,

Khan³

et al. 2018

AJBLS

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The biochemical parameters such as SGOT, SGPT, MDA, and uric acid levels were investigated for the assessment of stress-induced dysfunction after immobilization stress on the Swiss albino mice. Stress induction caused the elevation of SGOT (7.7 ± 0.2 vs 88.8 ± 0.3; control vs stress), SGPT (10.3 ± 0.5 vs 110.5 ± 5.2), MDA (3.9 ± 0.2 vs 9.4 ± 0.2 in the serum and 4.0 ± 0.3 vs 13.9 ± 0.2 in brain; control vs stress) and uric acid (7.0 ± 0.1 vs 17.2 ± 0.3; control vs stress) levels in the serum. Histopathology of the liver, kidney heart and lung were also examined, and morphology indicated the degradation of each of the organ by the stress induction. The bark of Loranthus globosus was extracted with methanol and then fractionated with petroleum ether (PE), chloroform (CF) and ethyl acetate (EA). Phytochemical screening confirmed the presence of flavanoids and phenolics in all fractions. The antioxidant activity was evaluated by in vitro assays using total antioxidant capacity and DPPH-free radical scavenging activity. The results demonstrated that among all the extractives of L. globosus EA fraction exhibited highest total antioxidant and free radical scavenging activity. The EA fraction of L. globosus (12 mg/kg b. w.) successfully reduced the increased biochemical parameters (stress vs stress + EAF); SGOT (88.8 ± 0.3 vs 9.9 ± 0.9), SGPT (110.5 ± 5.2 vs 14.6 ± 0.7), MDA (9.5 ± 0.2 vs 5.5 ± 0.1 in the serum; and 13.9 ± 0.2 vs 7.5 ± 0.2 in the brain) and serum uric acid (17.2 ± 0.3 vs 8.9 ± 0.1) on stress-induced mice. Histopathological analysis also supported the beneficial effects of EA fraction of L. globosus. Dexamethasone (2 mg/kg b. w.) was used as standard drug. The results suggested that the EA fraction of L. globosus might have some beneficial effects in preventing stress-induced organ dysfunction presumably through the neutralization of oxidative-stress generated during immobilization of mice. However, further study is necessary in order to precisely determine the exact molecular mechanisms.

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Section: Discussionsupporting

confidence: 81%

Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice

Rana¹,

Khatun²,

Khan³

et al. 2018

AJBLS

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“…[ 30 ], and Savoy cabbage cv. [ 31 ] but were slightly lower than those detected in Brassica oleracea L. var. capitata cv.…”

Section: Resultsmentioning

confidence: 63%

Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection

et al. 2018

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Nutritional value and disease-preventive effects of cabbage are well-known. Levels of the antioxidant compounds ascorbic acid (AA) and glucosinolates (GSL) in new Czech cabbage cultivars were determined in the context of different production systems. The contents of AA and GSLs in cabbage biomass were determined by HPLC. Individual GSLs were identified according to their exact masses with sinigrin used as the external standard. Artificial infection with A. brassicicola generally raised the AA levels. The major GSLs (≥10 mg kg−1) were glucobrassicin, sinigrin, and glucoiberin. Indole and aliphatic GSLs were present, but no aromatic ones were detected. Ecological growth conditions and the artificial fungal infection increased the total content of GSLs and, also, of the methoxylated indole GSLs. Sulforaphane, iberin, indole-3-carbinol, and ascorbigen resulting from the hydrolysis of GSLs were found in both cultivars. The amounts and profiles of GSLs present in the two Czech cultivars demonstrated their good nutritional value. The decomposition products sulforaphane, iberin, indole-3-carbinol, and ascorbigen detected improve its health-promoting qualities and represent a suitable component of the human diet.

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“…[6][7][8] Because of these many positive influences on human body, since the middle of the 19 th century, when the first references about CGAs appeared, there have been a high amount of articles dealing with extraction and detection techniques of CGAs or studying their influence on human health. CGAs have been observed and isolated in many plant materials such as coffee 9 , apple 10 , tomato, papaya 11 , sweet potato 12 , prune 13 , pear 14 , cabbage 15 , yacon 16 , burdock 17 , cherry 18 , apricot 19 , orange 20 , etc. Coffee beans are undoubtedly the most common observed matrix because coffee is the main source of CGAs.…”

Section: Introductionmentioning

confidence: 99%

Unremitting Problems With Chlorogenic Acid Nomenclature: A Review

Kremr¹,

Bajer²,

Bajerová³

et al. 2016

Química Nova

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Recebido em 08/12/2015; aceito em 12/01/2016; publicado na web em 12/04/2016 This paper summarizes a problematic nomenclature of isomers belonging to chlorogenic acid family since its first occurrence until present. During decades, there have been a high number of articles dealing with the family. Unfortunately, researchers who want to get knowledge about this topic may be strongly confused after reading a few articles. Due to gradual discoveries and isolations of the individual isomers from plenty of matrices and because of the changing system of terminology after these discoveries, discrepancies among articles are common. The cause of this confusion is that the main compound of the family, 5-caffeoylquinic acid (also wellknown as chlorogenic acid), was truly called as 3-caffeoylquinic acid before 1976, when new rules for nomenclature were published. Many researchers and also chemicals suppliers, however, keep using the "pre-IUPAC" nomenclature and wrongly call 3-caffeoylquinic acid as chlorogenic acid, the main substituent of the family. Despite there have been some works struggling with this issue, the problem is still appearing. Therefore, the present work was written.

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Bioactive compounds content and total antioxidant activity of two savoy cabbages

Cited by 15 publications

References 27 publications

Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice

Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice

Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection

Unremitting Problems With Chlorogenic Acid Nomenclature: A Review

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Bioactive compounds content and total antioxidant activity of two savoy cabbages

Cited by 15 publications

References 27 publications

Protective Effect of &lt;i&gt;Loranthus globosus&lt;/i&gt; on Stress-Induced Major Organ Dysfunctions in Mice

Protective Effect of &lt;i&gt;Loranthus globosus&lt;/i&gt; on Stress-Induced Major Organ Dysfunctions in Mice

Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection

Unremitting Problems With Chlorogenic Acid Nomenclature: A Review

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Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice

Protective Effect of <i>Loranthus globosus</i> on Stress-Induced Major Organ Dysfunctions in Mice