Bioactive Glasses: Advancing from Micro to Nano and Its Potential Application

Shi, Mengchao; Chang, Jiang; Wu, Chengtie

doi:10.1007/978-3-319-44249-5_6

Cited by 4 publications

(2 citation statements)

References 103 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, besides the chemical composition, the nanostructure of the surface plays an important role in promoting bone formation. It has been demonstrated that nanostructured surfaces can lead to rapid protein adsorption at the early stage of implantation, which subsequently mediates cellular responses, such as cell attachment and proliferation [ 15 , 16 , 17 ]. In recent years, mesoporous bioactive glasses (MBGs) have been developed as a new class of bioactive materials, and the most attractive feature is that they present an ordered mesoporous channel structure which, together with the chemical composition, leads to superior bioactivity to conventional bioactive glasses (BGs) [ 18 , 19 , 20 , 21 , 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

Mesoporous Bioactive Glass Functionalized 3D Ti-6Al-4V Scaffolds with Improved Surface Bioactivity

Leeflang

et al. 2017

Materials

Self Cite

View full text Add to dashboard Cite

Porous Ti-6Al-4V scaffolds fabricated by means of selective laser melting (SLM), having controllable geometrical features and preferable mechanical properties, have been developed as a class of biomaterials that hold promising potential for bone repair. However, the inherent bio-inertness of the Ti-6Al-4V alloy as the matrix of the scaffolds results in a lack in the ability to stimulate bone ingrowth and regeneration. The aim of the present study was to develop a bioactive coating on the struts of SLM Ti-6Al-4V scaffolds in order to add the desired surface osteogenesis ability. Mesoporous bioactive glasses (MBGs) coating was applied on the strut surfaces of the SLM Ti-6Al-4V scaffolds through spin coating, followed by a heat treatment. It was found that the coating could maintain the characteristic mesoporous structure and chemical composition of MBG, and establish good interfacial adhesion to the Ti-6Al-4V substrate. The compressive strength and pore interconnectivity of the scaffolds were not affected by the coating. Moreover, the results obtained from in vitro cell culture experiments demonstrated that the attachment, proliferation, and differentiation of human bone marrow stromal cells (hBMSCs) on the MBG-coated Ti-6Al-4V scaffolds were improved as compared with those on the conventional bioactive glass (BG)-coated Ti-6Al-4V scaffolds and bare-metal Ti-6Al-4V scaffolds. Our results demonstrated that the MBG coating by using the spinning coating method could be an effective approach to achieving enhanced surface biofunctionalization for SLM Ti-6Al-4V scaffolds.

show abstract

Section: Introductionmentioning

confidence: 99%

Mesoporous Bioactive Glass Functionalized 3D Ti-6Al-4V Scaffolds with Improved Surface Bioactivity

Leeflang

et al. 2017

Materials

Self Cite

View full text Add to dashboard Cite

show abstract

“…With sol-gel based processing methods, diverse types of porous scaffolds, coatings and complex structures can be formed. 20 There are two main paths of development: nanocomposites and hybrids. Sol-gel BG can be formed into nanoparticles and nanofibers.…”

Section: Introductionmentioning

confidence: 99%

Bioactive glass-based organic/inorganic hybrids: an analysis of the current trends in polymer design and selection

et al. 2023

View full text Add to dashboard Cite

show abstract

Fabrication and characterization of chlorhexidine gluconate loaded poly(vinyl alcohol)/45S5 nano‐bioactive glass nanofibrous membrane for guided tissue regeneration applications

et al. 2023

View full text Add to dashboard Cite

Polymeric barrier membranes are used in periodontal applications to prevent fibroblastic cell migration into the cavities of bone tissue and to properly guide the proliferation of tissues. In this study, the fabrication, characterization, bioactivity, and in vitro biological properties of polyvinyl alcohol‐based nanofibrous membranes containing nano‐sized 45S5 bioactive glass (BG) loaded with chlorhexidine (CH) gluconate with biocompatible, bioactive, and antibacterial properties for using as dental barrier membranes were investigated. Nanofibrous membranes with an average fiber diameter, pore size, and porosity of 210 nm, 24.73 μm, and 12.42%, respectively, were loaded with 1% and 2% CH, and the release profile was investigated. The presence of BG in the membranes promoted fibroblastic proliferation and the presence of CH provided antibacterial properties. Nanofibrous membranes exhibit a high ability to restrict bacterial growth while fulfilling the necessary conditions for use as a dental barrier thanks to their low swelling rates, significant surface bioactivities, and appropriate degradation levels.

show abstract

Bioactive Glasses: Advancing from Micro to Nano and Its Potential Application

Cited by 4 publications

References 103 publications

Mesoporous Bioactive Glass Functionalized 3D Ti-6Al-4V Scaffolds with Improved Surface Bioactivity

Mesoporous Bioactive Glass Functionalized 3D Ti-6Al-4V Scaffolds with Improved Surface Bioactivity

Bioactive glass-based organic/inorganic hybrids: an analysis of the current trends in polymer design and selection

Fabrication and characterization of chlorhexidine gluconate loaded poly(vinyl alcohol)/45S5 nano‐bioactive glass nanofibrous membrane for guided tissue regeneration applications

Contact Info

Product

Resources

About