The marine biosphere is the primary source that has produced excellent bioactive metabolites. Natural compounds isolated from various algae, especially brown algae, gained interest because of their wide variety of biological activities and biocompatibility. Among brown algae, Turbinaria ornata (T. ornata), a highly prevalent alga, because of the presence of bioactive substances, primarily polysaccharides and proteins, could be used for a broad range of pharmaceutical applications. Hence, this study focuses on the biological activity of T. ornata as reported in earlier studies, which includes antioxidant, anti-inflammatory, antidiabetic, antiproliferative, and neuroprotective effects. Also, a few natural compounds isolated from the Turbinaria species have been used for the biogenic nanoparticle synthesis that was considered to be potential for desired biological applications. This review gives detailed information on the valuable natural resources being used as a potential component in pharmaceutical applications.