Biodegradability and Swelling capacity of Kaolin based Chitosan-g-PHEMA Nanocomposite hydrogel

Pradhan, Arun Kumar; Rana, Pradeep Kumar; Sahoo, Prafulla Kumar

doi:10.1016/j.ijbiomac.2014.12.024

Cited by 40 publications

(14 citation statements)

References 24 publications

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“…The mechanical and thermal characteristics of different polymers can be improved by incorporating kaolin [124,125,126]. Polymeric dressings can be modified and functionalized to display interesting behaviors such as drug release and hemostatic characteristics [127,128].…”

Section: Biomedical Applications Of Polymer Compositesmentioning

confidence: 99%

Recent Overviews in Functional Polymer Composites for Biomedical Applications

2018

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Composite materials are considered as an essential part of our daily life due to their outstanding properties and diverse applications. Polymer composites are a widespread class of composites, characterized by low cost, facile processing methods, and varied applications ranging from daily-use issues to highly complicated electronics and advanced medical combinations. In this review, we focus on the most important fabrication techniques for bioapplied polymer composites such as electrospinning, melt-extrusion, solution mixing, and latex technology, as well as in situ methods. Additionally, significant and recent advances in biomedical applications are spotlighted, such as tissue engineering (including bone, blood vessels, oral tissues, and skin), dental resin-based composites, and wound dressing.

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Section: Biomedical Applications Of Polymer Compositesmentioning

confidence: 99%

Recent Overviews in Functional Polymer Composites for Biomedical Applications

2018

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“…The determined peak at 1406 cm -1 was shifted slightly to left by the increasing of amount of diatomite and the intensity of peak was decreased [12,21]. The C=O stretching and -COOH bending of acrylic acid were observed at 1557 cm -1 wavenumber [15,26]. The absorption peak at 1162 (C-O-C) cm -1 was attributed to the ester group in HEMA [27].…”

Section: Ftir Spectrums Of Samplesmentioning

confidence: 99%

“…For the equilibrium swelling degree (ESD) study, the swollen samples were dried until they reached the equilibrium at 100 o C in the oven and were measured gravimetrically [15]. ESD value was calculated from Eq.…”

Section: Swelling Propertiesmentioning

confidence: 99%

See 1 more Smart Citation

http://www.hjse.hitit.edu.tr/hjse/index.php/HJSE/article/view/45

Boran

Aktı

2015

Hittite J Sci Eng

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H eavy metal pollution is a serious environmental problem and it threats human health and ecosystem due to toxic and carcinogenic effects even at low concentrations. Many methods have been employed for the removal of heavy metals from water such as chemical precipitation, ion change, membrane separation and adsorption. Among the methods, adsorption is regarded as the most reliable choice due to technically and economically applicability [1][2][3][4].The hydrogels having three-dimensional networks of polymer chains have attracted great interests due to their high absorb, swell and water uptake capacities [5][6][7][8]. Many polymers such as polyacrylic acid (PAAc), poly (2-hydroxyethyl methacrylate, PHEMA), polyvinyl alcohol (PVA) are used in the synthesis of hydrogels. The hydrogels based on PHEMA and PAAc have been

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“…The easiness of preparation, the flexibility in modifying the polymer structure, the ability to control the drug release and protect it from degradation as well as the polymer swelling behaviour are all features encouraged its use in many biomedical and drug delivery applications. The chemical and thermal stability as well as biodegradability and biocompatibility of poly (2-hydroxyethyl methacrylate) based polymers have also made them attractive for many pharmaceutical and biomedical applications [16][17][18][19][20]. Mangiacotte et al [21] used HEMA in the development of polymeric mucoadhesive nanoparticles, as a potential ophthalmic drug delivery system.…”

Section: Introductionmentioning

confidence: 99%

Drug Release Control and Enhancement Using Carriers With Different Concentrations of Capmul® MCM C8

Bayan

2021

Int J App Pharm

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Objective: The main aim of this study was to design a drug carrier capable to control and enhance the release of poorly water soluble drugs. Methods: Three polymeric formulations, based on poly (2-hydroxyethyl methacrylate) and loaded with different Capmul® MCM C8 concentrations (0, 10 and 20 % w/w), were prepared. Felodipine, which is a poorly soluble substance, was selected as a model drug. The effect of Capmul® MCM C8 on swelling behavior and in vitro release profile of the prepared polymer was investigated in PBS. Results: The swelling profiles of allformulationswere statistically similar, which indicated the non-significant effect of added Capmul® MCM C8 on polymer's swelling behavior. All formulations showed a delayed drug release. Formulation-F3, which is loaded with 20% w/wCapmul® MCM C8 displayed a significant higher release compared to the other formulations. Conclusion: Capmul® MCM products, which are widely used in food industries, can be used to improve the oral delivery of poorly soluble substances. The optimized formulation exhibited the ability to control and enhance the release of the model drug.

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Biodegradability and Swelling capacity of Kaolin based Chitosan-g-PHEMA Nanocomposite hydrogel

Cited by 40 publications

References 24 publications

Recent Overviews in Functional Polymer Composites for Biomedical Applications

Recent Overviews in Functional Polymer Composites for Biomedical Applications

http://www.hjse.hitit.edu.tr/hjse/index.php/HJSE/article/view/45

Drug Release Control and Enhancement Using Carriers With Different Concentrations of Capmul® MCM C8

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