Biodegradable poly(diol citrate) nanocomposite elastomers for soft tissue engineering

Webb, Antonio R.; Kumar, Vivek; Ameer, Guillermo A.

doi:10.1039/b611353b

Cited by 38 publications

(22 citation statements)

References 38 publications

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“…However, the detailed study such as one performed by Tatai et al is necessary in order to optimise the polymer for future biomedical applications [34]. Similar to the p(OCS) material studied here, PGS and POC elastomers have been studied by other investigators for their potential use in tissue engineering applications [2,11,13,15,35]. Synthesis of all these materials is via catalyst-free polyesterification, and their structural properties are also similar and potentially suitable for fabrication of tissue engineering scaffolds.…”

Section: Hydrolytic Degradationmentioning

confidence: 91%

“…According to Yang et al the POC elastomers show inflammatory response that is similar to that shown by a standard PLGA with minimal fibrous capsule formation [3]. Apart from their easy thermal processabilities [12], the properties of elastomeric citrates could also be tailored by mixing them with natural bone mineral hydroxy apatite (HA) [10] or with PLLA [13] in order to meet specific tissue regeneration requirements.…”

Section: Introductionmentioning

confidence: 95%

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Synthesis and characterization of novel citric acid-based polyester elastomers

Djordjević

Choudhury

Dutta

et al. 2009

Polymer

124

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Section: Hydrolytic Degradationmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 95%

Synthesis and characterization of novel citric acid-based polyester elastomers

Djordjević

Choudhury

Dutta

et al. 2009

Polymer

124

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“…Nanoscale structures made from poly( l -lactic acid) (PLLA), poly(lactic-co-glycolic acid) (PLGA), hydroxyapatite (HA), multiwalled carbon nanotubes (MWCNTs), and modified nanofumed silica have all been incorporated into CBBs to increase the tensile strength and modulus of the material. Compared with POC controls, when PLLA or PLGA is incorporated as the nanophase into the POC network, an increase in the tensile strength and modulus from 1.51 ± 0.08 to 3.54 ± 0.35 MPa and 1.59 ± 0.13 to 17.73 ± 1.99 MPa, respectively, was observed (31). Nano-HA incorporated into poly[(1,2-propanediol-sebacate)-citrate] exhibits an 11.4- and 8.2-fold increase over controls in modulus and tensile strength, respectively (32).…”

Section: Fundamental Design Strategiesmentioning

confidence: 99%

Citrate-Based Biomaterials and Their Applications in Regenerative Engineering

Tran

Yang

Ameer

2015

Annu. Rev. Mater. Res.

Self Cite

115

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Advances in biomaterials science and engineering are crucial to translating regenerative engineering, an emerging field that aims to recreate complex tissues, into clinical practice. In this regard, citrate-based biomaterials have become an important tool owing to their versatile material and biological characteristics including unique antioxidant, antimicrobial, adhesive, and fluorescent properties. This review discusses fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering.

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“…Therefore, it is clear that the ES tube is a good candidate of artificial vascular graft as it shows similar strength of native coronary artery, which has tensile strength around 1.4-11.14 MPa. [57] …”

Section: Journal Of Biomaterials Science Polymer Edition 2035mentioning

confidence: 97%

Fabrication and characterisation of an electrospun tubular 3D scaffold platform of poly(vinylidene fluoride-co-hexafluoropropylene) for small-diameter blood vessel application

Ahmed

Choudhury

Dutta

et al. 2014

Journal of Biomaterials Science, Polymer Edition

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In this research, nanofibrous 3D tubular (~4-mm-diameter tube) scaffolds of poly (vinylidene fluoride-co-hexafluoropropylene) were fabricated by electrospinning. The role of surface charge in the success of these scaffolds for potential small-diameter artificial vascular grafts has been investigated using streaming potential study. Prior to endothelial cell culture, surface properties such as wettability and the surface charge of these tubular scaffolds were evaluated using unmodified and fibrinogen-adsorbed surfaces to understand their interaction with surrounding environment. The tubular scaffolds constructed using electrospinning show similar mechanical properties such as tensile strength and elastic modulus as those of native vessels. Whilst endothelial cell proliferation on unmodified tubes, as analysed by scanning electron microscopy, was found to be moderate, a simple process of dynamic fibrinogen adsorption was seen to enhance the endothelialisation of these tubular grafts. The high negative zeta potential values, high strength, robustness and structural reliability of the scaffolds represent them to be promising biomaterials for vascular graft applications.

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Biodegradable poly(diol citrate) nanocomposite elastomers for soft tissue engineering

Cited by 38 publications

References 38 publications

Synthesis and characterization of novel citric acid-based polyester elastomers

Synthesis and characterization of novel citric acid-based polyester elastomers

Citrate-Based Biomaterials and Their Applications in Regenerative Engineering

Fabrication and characterisation of an electrospun tubular 3D scaffold platform of poly(vinylidene fluoride-co-hexafluoropropylene) for small-diameter blood vessel application

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