Biological activities of some natural compounds fromSideritis sipylea Boiss

Abstract

In this work, several diterpenes including siderol, linearol and epicandicandiol were isolated from Sideritis sipylea Boiss collected from Izmir-Karaburun-Akdag, Turkey. In addition, diacetate derivatives of linearol and epicandicandiol were obtained. The antimicrobial activites of all these compounds against the bacteria Staphylococcus aureus (ATTC 25923), Bacillus subtilis (ATCC 6633), Escherichia coli (ATCC 11230), Pseudomonas aeruginosa (ATCC 27853) and the fungus Candida albicans (ATCC 90028) were studied. Antimicrobal activity was measured by the well-diffusion method. Except for C. albicans all microorganisms were tested against antibiotic discs in comparison with the studied compounds.

Sideritis spp.: Uses, chemical composition and pharmacological activities—A review

“…The 1,3-diolic function (present in 1-acetyljativatriol and its active derivatives, as well as in foliol (5) and isopusillatriol (6)) seems to be necessary for the antimicrobial activity of these compounds. Logoglu et al (2006) studied the antimicrobial activity of the diterpenoids siderol, linearol and epicandicandiol on Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli bacteria and the fungus Candida albicans. The only active compound was epicandicandiol, against Staphylococcus aureus and Bacillus subtilis and Candida albicans.…”

“…Most species are mainly found in the Mediterranean area, from Canary Islands and Madeira to Caucasus; Spain and Turkey possess the highest number of different species. In Spain, most of them are established in the Southeast of Iberian Peninsula and Canary Islands whereas Marmara and Aegean regions predominate in Turkey (Güvenç et al, 2005;Aslan et al, 2006;Logoglu et al, 2006).…”

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

“…In addition, the biological activity of extracts, essential oils and isolated pure compounds from these species were reported [10,11,[14][15][16][17][18]. There are some chemical studies performed on S. pisidica.…”

Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr(III) and Zn(II) complexes

“…An antifungal susceptibility test was used by Candida albicans Y-1200-NIH, Tokyo. The ligands and the complexes were tested for their antimicrobial activity by the well-diffusion method Logoglu et al, 2006). Each ligand and complex was kept dry at room temperature and dissolved (0.25 lg/ll) in DMSO.…”