Biological activity of common mullein, a medicinal plant

Türker, Arzu Uçar; Camper, N. D.

doi:10.1016/s0378-8741(02)00186-1

Cited by 123 publications

(68 citation statements)

References 19 publications

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“…Based on this information, the various extracts were evaluated for their antitumor properties using potato disc bioassay. The study results showed that petroleum ether extract significantly inhibited tumor formation on potato discs which indicates it could be a potential source of [21][22][23] . In potato disc assay, Agrobacterium soil bacteria were used which produces tumors of roots or stem of plants.…”

Section: Potato Disc Assaymentioning

confidence: 99%

Potential of Various Extracts of Tamarindus indica (Caesalpiniaceae) Leaves in the Treatment of Cancer

Dhasade¹,

Nirmal²,

Pal³

et al. 2015

Insight Cancer Research

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Background and Objective:Globally second most frequently observed disease after heart disease is "Cancer". Despite advances in cancer treatment over the past decades, the prognosis of patients with blood cancer has improved only to small extent. Thus, there is an urgent need to develop new and effective strategies for the prevention and treatment of this form of cancer. Hence, present study was undertaken to evaluate anticancer potential of leaves of Tamarindus indica Linn. (Caesalpiniaceae). Materials and Methods: The plant leaves were collected and extracted with various solvents like petroleum ether, ethanol, ethyl acetate, chloroform and water. Various extracts of leaves were screened for anticancer activity using the methods like potato disc method, onion root-tip assay and trypan blue assay by using HL-60 Cell line in dose dependent manner. Results: Petroleum ether extract of leaves of T. indica shows more potency as compared with other extracts in the treatment of cancer in all the tests performed. Conclusion: It can be concluded that petroleum ether extract of T. indica leaves have potency to prevent or manage cancer cell growth.

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Section: Potato Disc Assaymentioning

confidence: 99%

Potential of Various Extracts of Tamarindus indica (Caesalpiniaceae) Leaves in the Treatment of Cancer

Dhasade¹,

Nirmal²,

Pal³

et al. 2015

Insight Cancer Research

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“…However, there are no clinical trials that support these popular uses. Mullein contains harpagoside, harpagide, aucubin, hesperidin, verbascoside, saponins, and volatile oils (Turker and Camper, 2002).…”

Section: Mullein (Verbascum Densiflorum)mentioning

confidence: 99%

“…However, there are reports relating to the effects of mullein in vitro. For example, it has been shown that mullein has in vitro antiviral activity against influenza, herpes simplex viruses, herpes simplex virus type 1, and also an anti-bacterial activity against Klebsiella pneumonia, Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli (Turker and Camper, 2002). There are no existing reports about the toxicological effects of mullein in either experimental models or in human beings.…”

Section: Mullein (Verbascum Densiflorum)mentioning

confidence: 99%

Risks and benefits of commonly used herbal medicines in Mexico

Rodríguez‐Fragoso

Reyes‐Esparza

Burchiel

et al. 2008

Toxicology and Applied Pharmacology

167

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In Mexico, local empirical knowledge about medicinal properties of plants is the basis for their use as home remedies. It is generally accepted by many people in Mexico and elsewhere in the world that beneficial medicinal effects can be obtained by ingesting plant products. In this review, we focus on the potential pharmacologic bases for herbal plant efficacy, but we also raise concerns about the safety of these agents, which have not been fully assessed. Although numerous randomized clinical trials of herbal medicines have been published and systematic reviews and meta-analyses of these studies are available, generalizations about the efficacy and safety of herbal medicines are clearly not possible. Recent publications have also highlighted the unintended consequences of herbal product use, including morbidity and mortality. It has been found that many phytochemicals have pharmacokinetic or pharmacodynamic interactions with drugs. The present review is limited to some herbal medicine that are native or cultivated in Mexico and that have significant use. We discuss the cultural uses, phytochemistry, pharmacological and toxicological properties of the following following plant species: Nopal (Opuntia ficus), Peppermint (Mentha piperita), Chaparral (Larrea divaricata), Dandlion (Taraxacum officinale), Mullein (Verbascum densiflorum), Chamomile (Matricaria recutita), Nettle or Stinging Nettle (Urtica dioica), Passionflower (Passiflora incarmata), Linden Flower (Tilia europea), and Aloa (Aloa vera). We conclude that our knowledge of the therapeutic benefits and risks of some herbal medicines used in Mexico is still limited and efforts to elucidate them should be intensified.

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“…The plant is reported to be mildly diuretic and to have a soothing and anti-inflammatory effect on the urinary tract, and to act as a mild sedative. It has also been used as a domestic remedy for pneumonia, fever, congestion, allergies, migraine, catarrhs and colic (1)(2)(3). During our routine field excursions, it was found that this plant is used to treat respiratory tract infections and externally boils and abscesses.…”

Section: Introductionmentioning

confidence: 99%