Most indigenous medicinal plants to cure specific ailments from ancient time traditionally. Helecteres isora Linn. (Sterculiaceae) also called as Marodphali, Marorphali, Avartani, and Enthanietc due to screw like shape of fruit commonly known as Indian screw tree possess therapeutic, phytochemical and pharmacological valued medicinal plant in SouthEast Asia. The
Background and Objective:Globally second most frequently observed disease after heart disease is "Cancer". Despite advances in cancer treatment over the past decades, the prognosis of patients with blood cancer has improved only to small extent. Thus, there is an urgent need to develop new and effective strategies for the prevention and treatment of this form of cancer. Hence, present study was undertaken to evaluate anticancer potential of leaves of Tamarindus indica Linn. (Caesalpiniaceae). Materials and Methods: The plant leaves were collected and extracted with various solvents like petroleum ether, ethanol, ethyl acetate, chloroform and water. Various extracts of leaves were screened for anticancer activity using the methods like potato disc method, onion root-tip assay and trypan blue assay by using HL-60 Cell line in dose dependent manner. Results: Petroleum ether extract of leaves of T. indica shows more potency as compared with other extracts in the treatment of cancer in all the tests performed. Conclusion: It can be concluded that petroleum ether extract of T. indica leaves have potency to prevent or manage cancer cell growth.
Tamarindus indica Linn (Caesalpiniaceae) is a tropical evergreen tree, extensively used as traditional medicine in all countries. T. indica is commonly found in fertile areas throughout the Africa and Southern Asia. Even though this plant has gained scientific importance recently, there is a need for the pharmacognostic standardization. Hence, in the present work the leaf of the plant were subjected to various microscopical and physical evaluations. In the microscopical studies, the different cell structures and arrangements were studied and in physical evaluation the ash values and extractive values were studied. Pharmacognostic standardization of leaves of T. indica is necessary as it is highly potent commercially. The present study established macro and microscopic characteristics, physicochemical values and phytochemical screening of leaves of T. indica. The various pharmacognostic constants were obtained which could help in the development of a suitable monograph for the plant.
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