Biological activity of extracts from guayusa leaves (Ilex guayusa Loes.) obtained by supercritical CO2 and ethanol as cosolvent

Cadena-Carrera, Santiago Esmiro; Tramontin, Deise Parolo; Cruz, Alexandre Bella; Cruz, Ramón; Müller, Joachim D.; Hense, Haiko

doi:10.1016/j.supflu.2019.104543

Cited by 30 publications

(18 citation statements)

References 38 publications

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“…The addition of co-solvent presented a considerable increase in yield in both convective and vacuum dried samples (5.78%-6.48%). The increase in yield with the addition of the co-solvent is corroborated by the findings reported by Santos et al (2017) and Cadena-Carrera et al (2019). Santos et al (2017) indicated the presence of more polar mixtures can improve the solubility of different compounds.…”

Section: Influence Of Conditions On Yield Of Oilsupporting

confidence: 73%

A study of dried mandarin ( Clementina orogrande ) peel applying supercritical carbon dioxide using co‐solvent: Influence on oil extraction, phenolic compounds, and antioxidant activity

Quispe‐Fuentes

Uribe

López

et al. 2021

Food Processing Preservation

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Citrus fruits are one of the principal crops around the world, where Brazil is currently the largest producer of oranges, representing about 30% of the world's production of fresh fruit (Espinosa-Pardo et al., 2017a, 2017b. Oranges are the most important citrus in the agricultural area around the world, being widely grown in tropical, subtropical, and mild climate zones (Belo et al., 2018). Citrus fruits are members of the Rutaceae family, which is composed by around 160 genera and 1900 species (do Carmo et al., 2018). Mandarins are one of the fruits that belong to this family, and they are a subspecies of Clementine reticulate that is characterized for having a round elliptical shape, the trees are thornless and have an average height compared to other mandarins. The fruit is aromatic, juicy, and seedless, it also has a dark orange color and is made up of 8 to 12 segments, whereas its peel is soft and has a shiny red-orange-like color (Putnik et al., 2017).In the last years, mandarin has increased its consumption and marketing, and the production also increased to 30% reaching 29 millions of tons per year, being China the major producer

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Section: Influence Of Conditions On Yield Of Oilsupporting

confidence: 73%

A study of dried mandarin ( Clementina orogrande ) peel applying supercritical carbon dioxide using co‐solvent: Influence on oil extraction, phenolic compounds, and antioxidant activity

Quispe‐Fuentes

Uribe

López

et al. 2021

Food Processing Preservation

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“…Several technics are used in order to extract the phenolic compounds, such as extractions performed by supercritical fluid, microwave and ultrasounds, among others (Ali et al, 2018;Cadena-Carrera et al, 2019;Cong-Cong et al, 2017;Chemat et al, 2017;Irakli et al, 2018;Rodsamran and Sothornvit, 2019;Severini et al, 2017). Especially, the ultrasound-assisted extraction (UAE) is described as an efficient, green, economically viable, easy to operate and widely applicable method, even if its industrial scale-up presents several challenges.…”

Section: Introductionmentioning

confidence: 99%

Optimisation of ultrasound-assisted extraction of phenolic antioxidants from Ilex guayusa Loes. leaves using response surface methodology

Crespo

Radice

Sánchez

et al. 2020

Heliyon

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The present study carried out the optimisation of the total polyphenol content (TPC) extraction assisted by ultrasound in Ilex guayusa leaves applying response surface methodology (RSM). Also, the evaluation of the antioxidant activity of the extract obtained under the optimal extraction conditions was performed. The effect of the variables like, time of sonication, temperature, ethanol/water ratio and solid/liquid relationship and the interactions between them were analysed through the use of a factorial design 2^4. The significant factors were considered for the optimisation, employing a Box-Behnken Design, and the TPC as response variables. It was found that a quadratic model was adequate, with an adjusted R 2 value of 0.9367. The optimal conditions proposed, by the response surface model were: an extraction temperature of 60 C, sonication time of 29.9 min and ethanol/water ratio of 76.8/23.2. The optimised leaves extract of I. guayusa show a TPC of 3.46 (AE0.17) g gallic acid equivalents/100 g d.w. Radical scavenger activity of the obtained extract at optimum conditions, was performed through the FRAP and ABTS methods, given as result: 0.080 mmol TROLOX equivalents/100 g d.w. and 40.71 μmol TROLOX equivalents/g d.w., respectively. Due to the present findings, I. guayusa extracts can be proposed as a promising component for functional beverages, cosmetic and pharmaceutical formulation.

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“…Azevedo et al [ 80 ] evaluated the extraction of caffeine using SFE and found that near the critical point, below the crossover pressure, small increases in temperature result in a drastic decrease in the density of the solvent and, consequently, in its extraction capacity. For the extraction of artemisinin from Artemisia annua L., Rodrigues et al [ 81 ] found a crossover pressure of 200 bar, whereas Cadena-Carrera et al [ 82 ] evaluated the bioactive properties of the extracts from guayusa leaves ( Ilex guayusa Loes.) and found a crossover pressure close to 200 bar.…”

Section: Resultsmentioning

confidence: 99%

Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization

et al. 2020

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The objective of this study was to determine the best operational conditions for obtaining red propolis extract with high antioxidant potential through supercritical fluid extraction (SFE) technology, using carbon dioxide (CO2) as the supercritical fluid and ethanol as the cosolvent. The following parameters were studied: overall extraction curve, S/F (mass of CO2/mass of sample), cosolvent percentage (0, 1, 2 and 4%) and global yield isotherms as a function of different pressures (250, 350 and 450 bar) and temperatures (31.7, 40 and 50 °C). Within the investigated parameters, the best conditions found were an S/F of 131 and the use of ethanol at the highest concentration (4% w/w), which resulted in higher extract yields and higher content of antioxidant compounds. Formononetin, the main biomarker of red propolis, was the compound found at the highest amounts in the extracts. As expected, the temperature and pressure conditions also influenced the process yield, with 350 bar and 40 °C being the best conditions for obtaining bioactive compounds from a sample of red propolis. The novel results for red propolis found in this study show that it is possible to obtain extracts with high antioxidant potential using a clean technology under the defined conditions.

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Biological activity of extracts from guayusa leaves (Ilex guayusa Loes.) obtained by supercritical CO2 and ethanol as cosolvent

Cited by 30 publications

References 38 publications

A study of dried mandarin ( Clementina orogrande ) peel applying supercritical carbon dioxide using co‐solvent: Influence on oil extraction, phenolic compounds, and antioxidant activity

A study of dried mandarin ( Clementina orogrande ) peel applying supercritical carbon dioxide using co‐solvent: Influence on oil extraction, phenolic compounds, and antioxidant activity

Optimisation of ultrasound-assisted extraction of phenolic antioxidants from Ilex guayusa Loes. leaves using response surface methodology

Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization

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