Biological Properties and Characterization of Lectin from Red Kidney Bean (Phaseolus Vulgaris)

Zhang, Jianshe; Shi, John; Ilić, Sanja; Xue, Sophia Jun; Kakùda, Yukio

doi:10.1080/87559120802458115

Cited by 49 publications

(55 citation statements)

References 34 publications

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“…The highest significant value was recorded with Shalatine seeds (9.528 mg/g) followed by 10YLHJ49 (7.187 mg/g). This result is nearly in agreement with Zhang et al [14]. who recorded the lectin content in Phaseolus vulgaris seeds (red kidney beans) as 12 mg/g.…”

Section: Discussionsupporting

confidence: 93%

See 1 more Smart Citation

Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris Seeds

El-S¹,

El-A²,

S³

2017

J Microb Biochem Technol

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Section: Discussionsupporting

confidence: 93%

“…(25 g) were ground to a powder and 250 ml of 50 mM phosphate buffer (pH 7.2) were added [14]. Then, the homogenized powder in buffer was left overnight for complete extraction at 4°C.…”

Section: Blood Group Samplesmentioning

confidence: 99%

Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris Seeds

El-S¹,

El-A²,

S³

2017

J Microb Biochem Technol

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“…Lectins are carbohydrate-binding glycoproteins that can react specifi cally with human blood cells, preferentially agglutinate malignant cells, and undergo mitogenic stimulation of lymphocytes. Some lectins are resistant to heat and proteolytic enzymes and can enter the circulatory system intact [Zhang et al, 2009].…”

Section: Secondary Metabolites In Economically Important Cropsmentioning

confidence: 99%

Current Approaches for Enhanced Expression of Secondary Metabolites as Bioactive Compounds in Plants for Agronomic and Human Health Purposes

Jiménez-García¹,

Vazquez-Cruz²,

Guevara-González³

et al. 2013

Pol. J. Food Nutr. Sci.

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The study of secondary metabolism in plants is an important source for the discovery of bioactive compounds with a wide range of applications. Today these bioactive compounds derived from plants are important drugs such as antibiotics, and agrochemicals substitutes, they also have been economically important as fl avors and fragrances, dyes and pigments, and food preservatives. Many of the drugs sold today are synthetic modifi cations of naturally obtained substances. There is no rigid scheme for classifying secondary metabolites, but they can be divided into different groups based on their chemical components, function and biosynthesis: terpenoids and steroids, fatty acid-derived substances and polyketides, alkaloids, phenolic compounds, non-ribosomal polypeptides and enzyme cofactors. The increasing commercial importance of these chemical compounds has resulted in a great interest in secondary metabolism, particularly the possibility of altering the production of bioactive plant metabolites by means of tissue culture technology and metabolomics. In today's world the use of bioactive compounds derived from plants plays an important role in pharmaceutical applications. This review presents information about these metabolites and their applications as well as their importance in agronomy and bioactive effects on human health as nutraceuticals. This review includes also the new tendencies to produce these bioactive compounds under different stresses conditions such as biotic and abiotic stress that could be included in production systems.

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“…Phytohemagglutinin (PHA) in the seeds of the red kidney bean Phaseolus vulgaris consists of a tetramer of subunits E and L, and five different compositions of PHA have been identified, i.e., E4, E3L1, E2L2, E1L3, and L4 (2). All these P. vulgaris PHAs possess an agglutination activity against red blood cells as well as a mitogen activity against lymphocytes, and subunits E and L appear to be responsible for the former and latter activities, respectively (3).…”

Section: Introductionmentioning

confidence: 99%

“…P. vulgaris PHA has the potential as an agent against viral infection. Lectins isolated from the family of P. vulgaris beans, such as extra-long autumn purple beans, French beans, and Anasazi beans, exert inhibitory effects on the reverse transcriptase of human immunodeficiency virus in vitro (2,4). However, the antiviral activity of P. vulgaris PHA has not yet been demonstrated in vivo.…”

Section: Introductionmentioning

confidence: 99%

Protective effects of Phaseolus vulgaris lectin against viral infection in Drosophila

Ekowati

Arai

Putri

et al. 2017

DD&T

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Biological Properties and Characterization of Lectin from Red Kidney Bean (Phaseolus Vulgaris)

Cited by 49 publications

References 34 publications

Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris Seeds

Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris Seeds

Current Approaches for Enhanced Expression of Secondary Metabolites as Bioactive Compounds in Plants for Agronomic and Human Health Purposes

Protective effects of <i>Phaseolus vulgaris</i> lectin against viral infection in <i>Drosophila </i>

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