2014
DOI: 10.1016/j.jbiomech.2013.10.054
|View full text |Cite
|
Sign up to set email alerts
|

Biomechanical and structural response of healing Achilles tendon to fatigue loading following acute injury

Abstract: Achilles tendon injuries affect both athletes and the general population, and their incidence is rising. In particular, the Achilles tendon is subject to dynamic loading at or near failure loads during activity, and fatigue induced damage is likely a contributing factor to ultimate tendon failure. Unfortunately, little is known about how injured Achilles tendons respond mechanically and structurally to fatigue loading during healing. Knowledge of these properties remains critical to best evaluate tendon damage… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

6
73
0

Year Published

2015
2015
2021
2021

Publication Types

Select...
8

Relationship

3
5

Authors

Journals

citations
Cited by 67 publications
(79 citation statements)
references
References 39 publications
6
73
0
Order By: Relevance
“…Damage was significantly decreased only in the initial phase (5%) of fatigue life in the null group (figure 4b). Peak cyclic strain and damage increased while tangent stiffness and hysteresis decreased throughout fatigue life, as previously reported [20,43]. The null group had a significantly increased peak cyclic strain than the heterozygous group at 50% and both groups at 95% fatigue life (figure 4d).…”
Section: Tissue-level Fatigue Mechanicssupporting
confidence: 81%
See 2 more Smart Citations
“…Damage was significantly decreased only in the initial phase (5%) of fatigue life in the null group (figure 4b). Peak cyclic strain and damage increased while tangent stiffness and hysteresis decreased throughout fatigue life, as previously reported [20,43]. The null group had a significantly increased peak cyclic strain than the heterozygous group at 50% and both groups at 95% fatigue life (figure 4d).…”
Section: Tissue-level Fatigue Mechanicssupporting
confidence: 81%
“…An additional twenty specimens from each group were subjected to a fatigue loading protocol, as described previously [20,43]. Preliminary studies determined that the mean failure loads were significantly different between groups and as a result, all tendons were fatigue tested at 1 Hz between 20 and 75% of their ultimate failure load (0.75 -2.75 N for wild-type and heterozygous groups, 0.25-1.0 N for the null group).…”
Section: Fatigue Testingmentioning
confidence: 99%
See 1 more Smart Citation
“…The clamp was secured to the AT itself during experiment in order to eliminate any cofounding artifacts from muscle tissue. Specimens were placed in saline soaked gauze and frozen at -20°F 25 . Specimens were retrieved for testing and thawed slowly over a twentyfour hour period.…”
Section: Methodsmentioning
confidence: 99%
“…Considering that the tissue specimens of injured tendons are not available for histopathological examination in clinical practice, the ultrasound and magnetic resonance imaging are the gold standard in diagnosing tendon disorders, with ultrasonography being cost-effective, non-invasive and generally accessible [10,11,21]. Several animal models are currently used in tendinopathy research including laboratory animals, like rabbits [5,23,25,26,29,33], rats [9,15,17] and mice [8] as well as companion animals, like horses [2,3,31] and dogs [20]. Despite the fact that veterinary patients are increasingly recognised as translational models of human tendinopathies [19,30] their use in experimental protocols seems controversial and is not accepted in several countries due to ethical issues.…”
Section: Introductionmentioning
confidence: 99%