Biomechanical Differences of Coflex-F and Pedicle Screw Fixation in Stabilization of TLIF or ALIF Condition - A Finite Element Study

Lo, Cheng Chan; Tsai, Kai Jow; Zhong, Zheng Cheng; Hung, Ching-Hua

doi:10.1007/978-3-642-14515-5_144

Cited by 1 publication

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“…Although MIS-TLIF is favored compared to open TLIF [ 10 ], its efficacy and safety depends on surgeon expertise, which could be further enhanced through recent technological developments such as imaging and guiding techniques. The prime objective of fusion is to stabilize degenerated lumber segments through minimizing movement, relaxing spinal nerve, and lowering the pain [ 11 ]. The fusion stability is critically affected by suitable positioning of the pedicle screw [ 12 ], and therefore, continuous effort is being made to improve screw design.…”

Section: Introductionmentioning

confidence: 99%

Understanding the Future Prospects of Synergizing Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgery with Ceramics and Regenerative Cellular Therapies

Tsai

Yang

et al. 2021

IJMS

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Transforaminal lumber interbody fusion (TLIF) is the last resort to address the lumber degenerative disorders such as spondylolisthesis, causing lower back pain. The current surgical intervention for these abnormalities includes open TLIF. However, in recent years, minimally invasive TLIF (MIS-TLIF) has gained a high momentum, as it could minimize the risk of infection, blood loss, and post-operative complications pertaining to fusion surgery. Further advancement in visualizing and guiding techniques along with grafting cage and materials are continuously improving the safety and efficacy of MIS-TLIF. These assistive techniques are also playing a crucial role to increase and improve the learning curve of surgeons. However, achieving an appropriate output through TLIF still remains a challenge, which might be synergized through 3D-printing and tissue engineering-based regenerative therapy. Owing to their differentiation potential, biomaterials such as stem/progenitor cells may contribute to restructuring lost or damaged tissues during MIS-TLIF, and this therapeutic efficacy could be further supplemented by platelet-derived biomaterials, leading to improved clinical outcomes. Thus, based on the above-mentioned strategies, we have comprehensively summarized recent developments in MIS-TLIF and its possible combinatorial regenerative therapies for rapid and long-term relief.

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Section: Introductionmentioning

confidence: 99%