Biomimetic apatite coatings on micro-arc oxidized titania

Song, Woo‐Jin; Jun, Youn-Ki; Han, Yuexin; Hong, Sung Je

doi:10.1016/j.biomaterials.2003.09.103

Cited by 392 publications

(233 citation statements)

References 47 publications

Supporting

Mentioning

217

Contrasting

Unclassified

Order By: Relevance

“…Ca-P solution such as the simulated body fluid (SBF) has been frequently used for the biomimetic Ca-P coating to increase the bioactivity and successfully applied to implant materials for some special dental and medical cases [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Apatite formation on carbon nanotubes

Akasaka

Watari

Sato

et al. 2006

Materials Science and Engineering: C

123

View full text Add to dashboard Cite

Apatite coating on carbon nanotubes (CNTs) was done with a biomimetic coating method. The multi-walled CNTs (MWNTs) of curled shape with about 30 nm in diameter were immersed for 2 weeks in the simulated body fluid. Observation by scanning electron microscopy (SEM) showed the formation of apatite on the MWNTs surface. The clusters of spherules consisting of needle shape of apatite crystallites were massively grown on the aggregated MWNTs.The crystallites of 100 nm in width and 200-500 nm in length were grown perpendicularly to the longitudinal direction and radially originating from a common center of a single MWNT. Thus the architecture of crystalline apatite at nano-scale levels could be produced by simple method and the MWNT may be acting as core for initial crystallization of apatite.

show abstract

Section: Introductionmentioning

confidence: 99%

Apatite formation on carbon nanotubes

Akasaka

Watari

Sato

et al. 2006

Materials Science and Engineering: C

123

View full text Add to dashboard Cite

show abstract

“…20,21) The XRD peaks for HAp particles reveal that HAp particles are incorporated in the oxide film with no loss of crystallinity. Interestingly, CaTiO 3 , which is known to play a key role in the induction of bone-like apatite through the formation of Ti-OH, 19,22,23) was detected as clear peaks. CaTiO 3 is considered to be produced by Ca 2þ ions from HAp being incorporated in Ti substrates by the spark discharge energy.…”

Section: Characterization Of the Anodized Materialsmentioning

confidence: 99%

Surface Characteristics of Titanium Oxide Films Prepared by Micro-Arc Oxidation: Comparison of Direct Current Electrolysis and Pulse Electrolysis

et al. 2011

View full text Add to dashboard Cite

Oxide layers formed by micro-arc oxidation (MAO) using direct current electrolysis and pulse electrolysis were characterized by scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy and adhesive strength measurements. Ti oxide films fabricated by pulse electrolysis were found to have a significantly higher adhesive strength than those fabricated by direct current electrolysis. This can be explained by the different interface adhesive strengths between the two Ti oxide layers and the Ti substrate, as revealed by cross-sectional SEM micrographs. In addition, the dependences of the voltage and the current on the electrolysis time were investigated.

show abstract

“…Various techniques have been explored to modify the surfaces of Ti and its alloys to improve their osseointegration, including plasma spraying, sol-gel method, and electrochemical deposition [2][3][4][5][6][7][8][9][10][11][12] . Among these modification methods, micro-arc oxidation (MAO) has attracted special attention since it is a relatively convenient and effective technique for depositing oxide coatings on the surfaces of nonferrous metals [9][10][11][12] . More importantly, by using this technique, various desired elements can be introduced into the coated layers with porous structures 11) , such as calcium (Ca), phosphorus (P), magnesium (Mg) and strontium (Sr), which are trace elements in the human body playing a significant role in bone formation.…”

Section: Introductionmentioning

confidence: 99%

Effect of strontium ions on calcification of preosteoblasts cultured on porous calcium- and phosphate-containing titanium oxide layers formed by micro-arc oxidation

et al. 2016

View full text Add to dashboard Cite

INTRODUCTIONTitanium (Ti) and its alloys have been used in dentistry as implant materials because of their good mechanical properties, high corrosion resistance, and low cytotoxicity. However, their poor bone fusion properties limit their clinical applications 1) . Various techniques have been explored to modify the surfaces of Ti and its alloys to improve their osseointegration, including plasma spraying, sol-gel method, and electrochemical deposition [2][3][4][5][6][7][8][9][10][11][12] . Among these modification methods, micro-arc oxidation (MAO) has attracted special attention since it is a relatively convenient and effective technique for depositing oxide coatings on the surfaces of nonferrous metals [9][10][11][12] . More importantly, by using this technique, various desired elements can be introduced into the coated layers with porous structures 11) , such as calcium (Ca), phosphorus (P), magnesium (Mg) and strontium (Sr), which are trace elements in the human body playing a significant role in bone formation.Sr is considered a bioactive element that improves implant osseointegration. As was previously reported, Sr ions have been shown to enhance bone collagen synthesis and decrease bone resorption by inhibiting osteoclast resorbing activity [13][14][15][16][17][18][19][20] . Therefore, it is expected that a local release of Sr ions from implant surfaces would directly improve implant osseointegration.Since our previous studies have shown that MAO is a promising method to produce porous and firmly adherent bone formation concerned elements contained oxide deposition layers on metal substrates 11) , it is easy to optimize the Sr amounts introduced into the oxide deposition layers by altering MAO electrolyte compositions. Moreover, except for the first several days, a long-term stable release of metallic ions from the oxide deposition layers can be achieved by using the microporous structures formed during the MAO process 8) . In this study, Ti surfaces were modified by MAO using electrolytes with different Sr concentrations to promote calcification of preosteoblasts. Morphologies and elemental compositions of the surfaces as well as cross-sections of the Ti specimens obtained with and without MAO were characterized by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). A mouse preosteoblast MC3T3-E1 was utilized to study the calcification effect of Sr contents in the MAO-deposited layers on the Ti substrates in vitro. Osteogenic differentiation and calcified depositions of the MC3T3-E1 cells cultured on all specimens were evaluated using alkaline phosphatase (ALP) activity assay and alizarin red s staining, respectively. MATERIALS AND METHODS Ti substrate preparationCommercially pure Ti discs (grade 2, 8 mmφ×2.0 mm in thickness, Rare Metallic, Tokyo, Japan) were used in this study. Before the MAO treatment, Ti discs were mechanically polished with up to #800-grid SiC abrasive paper and then ultrasonically rinsed in acetone and ethanol. The obtained specimens (not subjected to...

show abstract

Biomimetic apatite coatings on micro-arc oxidized titania

Cited by 392 publications

References 47 publications

Apatite formation on carbon nanotubes

Apatite formation on carbon nanotubes

Surface Characteristics of Titanium Oxide Films Prepared by Micro-Arc Oxidation: Comparison of Direct Current Electrolysis and Pulse Electrolysis

Effect of strontium ions on calcification of preosteoblasts cultured on porous calcium- and phosphate-containing titanium oxide layers formed by micro-arc oxidation

Contact Info

Product

Resources

About