Biopolymers for Health, Food, and Cosmetic Applications

Augustine, Robin; Ramesh, R.; Cvelbar, Uroš; Mozetič, Miran; George, Anne

doi:10.1002/9783527652457.ch27

Cited by 42 publications

(15 citation statements)

References 126 publications

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“…The EPS from the halophilic bacterium Salipiger mucosus A3 T , which shows good emulsifying capacity, contains a protein concentration of 1.6 % (w/w) which was comparable to that of the EPS of H. turkmenica (1.4 %) (Llamas et al 2010). Substances with moisture-retention capacity are usually used in cosmetic, food, and pharmaceutical industries (Augustine et al 2013). Chitosan, HA, and sodium alginate, employed in several sectors for their good moistureabsorption and retention abilities, were chosen as comparison compounds to test the EPS moisture-absorption and retention capacities.…”

Section: Discussionmentioning

confidence: 98%

Production and properties of an exopolysaccharide synthesized by the extreme halophilic archaeon Haloterrigena turkmenica

Squillaci

Finamore

Paola

et al. 2015

Appl Microbiol Biotechnol

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We have isolated a novel exopolysaccharide (EPS) produced by the extreme halophilic archaeon Haloterrigena turkmenica. Some features, remarkable from an industrial point of view, such as emulsifying and antioxidant properties, were investigated. H. turkmenica excreted 20.68 mg of EPS per 100 ml of culture medium when grown in usual medium supplemented with glucose. The microorganism excreted the biopolymer mainly in the middle exponential growth phase and reached the maximal production in the stationary phase. Analyses by anion exchange chromatography and SEC-TDA Viscotek indicated that the EPS was composed of two main fractions of 801.7 and 206.0 kDa. It was a sulfated heteropolysaccharide containing glucose, galactose, glucosamine, galactosamine, and glucuronic acid. Studies performed utilizing the mixture of EPS anionic fractions showed that the biopolymer had emulsifying activity towards vegetable oils comparable or superior to that exhibited by the controls, moderate antioxidant power when tested with 2,2'-diphenyl-1-picrylhydrazyl (DPPH(·)), and moisture-retention ability higher than hyaluronic acid (HA). The EPS from H. turkmenica is the first exopolysaccharide produced by an archaea to be characterized in terms of properties that can have potential biotechnological applications.

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Section: Discussionmentioning

confidence: 98%

Production and properties of an exopolysaccharide synthesized by the extreme halophilic archaeon Haloterrigena turkmenica

Squillaci

Finamore

Paola

et al. 2015

Appl Microbiol Biotechnol

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“…15 Poly(E-caprolactone) (PCL) has got a lot of attention in biomedical applications due to its biocompatibility and biodegradability, and has been suggested for wide range of biomedical applications. [16][17][18] Materials with nano/submicro architectures are promising for skin tissue engineering due to their ability to support keratinocyte proliferation, reduce scar formation and inhibit bacterial growth over the material. 19 Electrospinning is an excellent technology used for the fabrication of nonwoven, three-dimensional, porous, and nano or submicron scale fiber-based matrices.…”

Section: Additional Supporting Information May Be Found In the Onlinementioning

confidence: 99%

Electrospun poly(ε‐caprolactone)‐based skin substitutes: In vivo evaluation of wound healing and the mechanism of cell proliferation

et al. 2014

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In the present study, we have fabricated electrospun poly(ε-caprolactone)-based membranes, characterized and studied the in vivo cell migration and proliferation and wound healing activity. Moreover, we did not seed any cells prior to the animal implantation and we could observe excellent fibroblast attachment and cell proliferation. Further full thickness excision wound on guinea pig completely healed within 35 days. We could reach in an assumption that the enhanced cell proliferation and wound healing might be due to the surface degradation of the polymer under physiological conditions and the formation of functional groups like hydroxyl and carboxyl groups that promoted cell proliferation in a cell adhesion protein mediated mechanism. This study is a novel tissue engineering concept for the reconstruction of a damaged tissue without the in vitro cell seeding and proliferation prior to the in vivo implantation.

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“…The traditional wound dressings sustained for over 40-45 years, which were then replaced by the advanced materials which comprise of thin films that are permeable to vapor and gases. Examples of such film wound dressings include alginates, polyurethane films and hydrogels (Augustine et al 2013(Augustine et al , 2014b.…”

Section: Introductionmentioning

confidence: 99%

Electrospun PCL membranes incorporated with biosynthesized silver nanoparticles as antibacterial wound dressings

2015

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An open wound is highly prone to bacterial colonization and infection. Bacterial barrier property is an important factor that determines the success of a wound coverage material. Apart from the bacterial barrier property, presence of antibacterial agents can successfully eliminate the invasion and colonization of pathogen in the wound. Silver nanoparticles are well-known antimicrobial agents against a wide range of microorganisms. Biosynthesized silver nanoparticles are more acceptable for medical applications due to superior biocompatibility than chemically synthesized ones. Presence of biomolecules on biosynthesized silver nanoparticles enhances its therapeutic efficiency. Polycaprolactone (PCL) is a well-known material for biomedical applications including wound dressings. Electrospinning is an excellent technique for the fabrication of thin membranes for wound coverage applications with barrier property against microbes. In this paper, we report the fabrication and characterization of electrospun PCL membranes incorporated with biosynthesized silver nanoparticles for wound dressing applications.

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Biopolymers for Health, Food, and Cosmetic Applications

Cited by 42 publications

References 126 publications

Production and properties of an exopolysaccharide synthesized by the extreme halophilic archaeon Haloterrigena turkmenica

Production and properties of an exopolysaccharide synthesized by the extreme halophilic archaeon Haloterrigena turkmenica

Electrospun poly(ε‐caprolactone)‐based skin substitutes: In vivo evaluation of wound healing and the mechanism of cell proliferation

Electrospun PCL membranes incorporated with biosynthesized silver nanoparticles as antibacterial wound dressings

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