Biopolymers for tissue engineering applications: A review

Biswal, Trinath

doi:10.1016/j.matpr.2020.09.628

Cited by 101 publications

(56 citation statements)

References 24 publications

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“…Bone had been named the greatest intelligent material historically and most precisely due to its limited regenerative flexibility. The freshly cured bone with adjacent host bone and, most importantly, the native bone functions include bone fusion [128,129]. Functional bone tissue engineering adds to functional and architectural diversity; the bone is an exceedingly complex tissue.…”

Section: Tissue Engineering (Te)mentioning

confidence: 99%

Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends

Veeman

Sai

Sureshkumar³

et al. 2021

International Journal of Polymer Science

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As a technique of producing fabric engineering scaffolds, three-dimensional (3D) printing has tremendous possibilities. 3D printing applications are restricted to a wide range of biomaterials in the field of regenerative medicine and tissue engineering. Due to their biocompatibility, bioactiveness, and biodegradability, biopolymers such as collagen, alginate, silk fibroin, chitosan, alginate, cellulose, and starch are used in a variety of fields, including the food, biomedical, regeneration, agriculture, packaging, and pharmaceutical industries. The benefits of producing 3D-printed scaffolds are many, including the capacity to produce complicated geometries, porosity, and multicell coculture and to take growth factors into account. In particular, the additional production of biopolymers offers new options to produce 3D structures and materials with specialised patterns and properties. In the realm of tissue engineering and regenerative medicine (TERM), important progress has been accomplished; now, several state-of-the-art techniques are used to produce porous scaffolds for organ or tissue regeneration to be suited for tissue technology. Natural biopolymeric materials are often better suited for designing and manufacturing healing equipment than temporary implants and tissue regeneration materials owing to its appropriate properties and biocompatibility. The review focuses on the additive manufacturing of biopolymers with significant changes, advancements, trends, and developments in regenerative medicine and tissue engineering with potential applications.

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Section: Tissue Engineering (Te)mentioning

confidence: 99%

Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends

Veeman

Sai

Sureshkumar³

et al. 2021

International Journal of Polymer Science

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“…Nature offers a variety of biopolymers with multiple attractive functions and beneficial properties for tissue engineering; bioresorbability, as an example, is the ability of a material to degrade within the host tissue at the appropriate rate and is a highly desirable property that can only be found in some biopolymers but not in industrial or inorganic ones [ 97 , 98 , 99 ]. The regeneration of rough tissues such as cartilage and bone requires tunable Poisson’s ratio scaffolds.…”

Section: Biopolymer-based Aerogels In Tissue Engineering and Regenerative Medicinementioning

confidence: 99%

Insights into the Role of Biopolymer Aerogel Scaffolds in Tissue Engineering and Regenerative Medicine

et al. 2021

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The global transplantation market size was valued at USD 8.4 billion in 2020 and is expected to grow at a compound annual growth rate of 11.5% over the forecast period. The increasing demand for tissue transplantation has inspired researchers to find alternative approaches for making artificial tissues and organs function. The unique physicochemical and biological properties of biopolymers and the attractive structural characteristics of aerogels such as extremely high porosity, ultra low-density, and high surface area make combining these materials of great interest in tissue scaffolding and regenerative medicine applications. Numerous biopolymer aerogel scaffolds have been used to regenerate skin, cartilage, bone, and even heart valves and blood vessels by growing desired cells together with the growth factor in tissue engineering scaffolds. This review focuses on the principle of tissue engineering and regenerative medicine and the role of biopolymer aerogel scaffolds in this field, going through the properties and the desirable characteristics of biopolymers and biopolymer tissue scaffolds in tissue engineering applications. The recent advances of using biopolymer aerogel scaffolds in the regeneration of skin, cartilage, bone, and heart valves are also discussed in the present review. Finally, we highlight the main challenges of biopolymer-based scaffolds and the prospects of using these materials in regenerative medicine.

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“…In addition, tissues can be divided into smaller functional segments that are imitated by specific anatomical structures such as self-organisation of larger organs [7]. These fundamental properties of tissue engineering, along with an in-depth knowledge of the ideal biological structure in the fields of engineering, biophysics, imaging, cell biology, biomaterials and medicine, was utilized using threedimensional printing technologies in the context of Bio printing to produce appropriate tissue [8][9][10]. While it is understood that this technology can produce material tissue•s -1 ubstance for tissue engineering, it is limited by its inability to replicate the desirable characteristics present in vivo.…”

Section: Fig 2 Electric Spinning Process and Numerical Notation Of Electro Spun Jets [1; 2]mentioning

confidence: 99%

The amber nano fibers development prospects to expand the capabilites of textile 3D printing in the general process of fabrication methods

Viļuma-Gudmona

Ļašenko

Sanchaniya

et al. 2021

Engineering for Rural Development

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The amber nano fibres are bio-active composites which could be applied in three-dimensional printing. The idea of using the amber for creating a new 3D printing material, including technological composition of the innovative amber nano and micro fibres is based on the hypothesis that organic compounds of succinite have an effective impact on living cells, including reparative, stimulating, for sedative effects as well protective properties from electro-magnetic field. To produce amber nano fibres, bioactive components were used that were isolated from the succinite and tested (in vitro) in the scientific laboratories. Three-dimensional printing is an emerging technology, which has been initially used to design and generate three-dimensional structures mainly for transplantation therapies. This process, which can be used for a variety of polymers, is becoming an increasingly essential component of biotechnological advancements. This article discusses the foundations of this technology, namely the processes used in conventional three-dimensional printing; it also discusses tissue engineering, a discipline of which new implementations of this technology are used as bio printing. The shortcomings of tissue engineering are addressed, including the failure of existing technology to manufacture nanofiber-based constructs used in blood vessels, cartilage, artery valves, tendon, cardiac muscle valves, muscle, and cornea. From this need for nanofiber processing, electrospinning is proposed as a possible roadmap for imminent tissue engineering threedimensional printing technologies, and finally, the latest integration of this technology with three-dimensional printing is addressed, highlighting the existing shortcomings in maintaining mandatory nano resolutions.

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Biopolymers for tissue engineering applications: A review

Cited by 101 publications

References 24 publications

Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends

Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends

Insights into the Role of Biopolymer Aerogel Scaffolds in Tissue Engineering and Regenerative Medicine

The amber nano fibers development prospects to expand the capabilites of textile 3D printing in the general process of fabrication methods

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