Bisphenol A and its structural analogues in infant formulas available in the Brazilian market: Optimisation of a UPLC-MS/MS method, occurrence, and dietary exposure assessment

Petrarca, Mateus Henrique; Perez, Mary Angela Favaro; Tfouni, Sílvia Amélia Verdiani

doi:10.1016/j.foodres.2022.111692

Cited by 13 publications

(3 citation statements)

References 39 publications

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“…For instance, the detection rates of BPA, BPS, BPF, BPAF, bisphenol M (BPM), and bisphenol TMC (BPTMC) have been estimated to be >50% in baby bottles available commercially [ 27 ]. In Brazil, bisphenol compounds ranging from 10.9 to 198.9 μg/kg in concentration have been detected in 22 types of infant formula [ 28 ]. Additionally, children can be exposed to BPA through plastic toys at childcare facilities [ 29 ].…”

Section: Contamination Status Of Bisphenolsmentioning

confidence: 99%

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

Wu,

Tian,

Zhu

et al. 2023

Toxics

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Reproductive disorders are considered a global health problem influenced by physiological, genetic, environmental, and lifestyle factors. The increased exposure to bisphenols, a chemical used in large quantities for the production of polycarbonate plastics, has raised concerns regarding health risks in humans, particularly their endocrine-disrupting effects on female reproductive health. To provide a basis for future research on environmental interference and reproductive health, we reviewed relevant studies on the exposure patterns and levels of bisphenols in environmental matrices and humans (including susceptible populations such as pregnant women and children). In addition, we focused on in vivo, in vitro, and epidemiological studies evaluating the effects of bisphenols on the female reproductive system (the uterus, ovaries, fallopian tubes, and vagina). The results indicate that bisphenols cause structural and functional damage to the female reproductive system by interfering with hormones; activating receptors; inducing oxidative stress, DNA damage, and carcinogenesis; and triggering epigenetic changes, with the damaging effects being intergenerational. Epidemiological studies support the association between bisphenols and diseases such as cancer of the female reproductive system, reproductive dysfunction, and miscarriage, which may negatively affect the establishment and maintenance of pregnancy. Altogether, this review provides a reference for assessing the adverse effects of bisphenols on female reproductive health.

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Section: Contamination Status Of Bisphenolsmentioning

confidence: 99%

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

Wu,

Tian,

Zhu

et al. 2023

Toxics

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“…Various analytical techniques have been used by different authors for the determination and quantification of BPA and its analogues, such as high-performance liquid chromatography coupled to a fluorescence detector (HPLC–FLD), 30 high-performance liquid chromatography coupled to a diode array detector (HPLC–DAD), 31 Online enrichment-HPLC–FLD, 32 ultra-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS), 33 gas chromatography–mass spectrometry (GC–MS), 34 liquid chromatography tandem mass spectrometry (LC–MS/MS). 27 Among these techniques, the GC–MS technique has certain benefits such as low equipment cost, less solvent usage, ease of analysis, and reliable results.…”

Section: Introductionmentioning

confidence: 99%

Gas chromatography–mass spectrometric determination of bisphenol residues by dispersive solid phase extraction followed by activated carbon spheres cleanup from fish feed samples

Talari

Ganji

Tiruveedula³

2023

Eur J Mass Spectrom (Chichester)

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Bisphenols are known endocrine disruptors commonly utilized in food packaging and storage materials, which frequently come into touch with multiple food products packed in them. The bisphenols in fish feed and other feed materials for aquatic organisms are harmful. The consumption of such marine foods is hazardous. Hence, the feed of aquatic products needs to be verified for the presence of bisphenols. The present study was focused on developing and validating a rapid, selective, and sensitive method to quantify 11 bisphenols from the fish feed with dispersive solid-phase extraction, which was cleaned by an optimized amount of activated carbon spheres and silylated by N,O-bis(trimethylsilyl)trifluoro acetamide and analyzed by gas chromatography–mass spectrometry. The new method was rigorously tested and verified after carefully tuning various parameters affecting analyte recovery. Limit of detection (LOD) were set at 0.5–5 ng/g and limit of quantification (LOQ) at 1–10 ng/g, respectively, resulting in 95–114% recoveries. Interday and intraday precisions in terms of relative standard deviation were found to be less than 11%. The proposed approach was effectively applied in floating and sinking fish feeds. The obtained results showed that higher concentration of bisphenol A, followed by bisphenol TMC, and bisphenol M at a concentration of 256.10, 159.01, and 168.82 ng/g in floating feed and 88.04, 200.79, and 98.03 ng/g in sinking feed samples, respectively.

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“…The deterministic approach is a simple and easily parallelized approach that performed with an 'optimist suppose' on each individual evaluation parameter and calculates the risk quotient based on the exposure concentration and the threshold, which is frequently utilized for the quantitative exposure assessment, such as food consumption, chemical occurrence evaluation, and so on (Rajasekhar et al, 2020;Kaur et al, 2020;Petrarca, et al, 2022;Ayyildiz, et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Dietary Exposure Risk Assessment of Pyrethroids in Fruits and Vegetables: A National Scale Investigation

Chen

et al. 2023

Preprint

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The pyrethroids (PYRs) were extensively used to increase agriculture outputs. However, the cumulative exposures of PYRs would bring about potential risks through food intake. It is in urgent requirement to explore the cumulative exposures on the fruits and vegetables. In this study, a total of 1720 samples incorporating eight primary fruits and vegetables collected around China were investigated to assess the health risk for adults and children from eight PYRs. The relative potency factor (RPF) method was employed to reveal both chronic and acute cumulative exposure. As a result, the hazard index (HI) were 0.004%~0.200% and 11.85%~99.19% for chronic and acute cumulative dietary exposure, respectively. The national wide investigation indicated the cumulative assessments were not hazardous. Besides, the acute intake of pear, grape, and lettuce should be paid on more attention, particularly. This study provides compelling evidence to develop relative policy and regulation to improve the food quality and safety.

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Bisphenol A and its structural analogues in infant formulas available in the Brazilian market: Optimisation of a UPLC-MS/MS method, occurrence, and dietary exposure assessment

Cited by 13 publications

References 39 publications

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

Gas chromatography–mass spectrometric determination of bisphenol residues by dispersive solid phase extraction followed by activated carbon spheres cleanup from fish feed samples

Dietary Exposure Risk Assessment of Pyrethroids in Fruits and Vegetables: A National Scale Investigation

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