Blood component use in critically ill patients

Rao, M. P.; Boralessa, H.; Morgan, C.; Soni, Neil; Goldhill, D. R.; Brett, Stephen; Contreras, M.

doi:10.1046/j.1365-2044.2002.02514.x

Cited by 104 publications

(85 citation statements)

References 18 publications

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“…Approximately 40% of the cohort received transfusions during the course of their ICU stay, and the mean pretransfusion hemoglobin level was 84 g/l [1]. A similar study in the United Kingdom confirmed these observations [13]. Unlike other cross-sectional studies, we observed that RBC transfusions in our study were less frequent than previously reported (21 vs. 40–50%) [1,2,14].…”

Section: Discussioncontrasting

confidence: 53%

Blood Transfusion Practice in Critically Ill Patients: A Single Institutional Experience

Al-Faris¹,

Al-Fares

Malek

et al. 2012

Med Princ Pract

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Objectives: To assess the transfusion practice in the intensive care unit (ICU) in a general hospital in Kuwait relative to indications, pretransfusion hemoglobin, red blood cell (RBC) use and outcome. Subjects and Methods: 475 patients were admitted to the ICU during the study period (January 2009 to February 2010). Ninety-nine received RBC transfusion. Demographic, clinical and transfusion data were prospectively collected for the 99 patients who were followed up for 30 days, until hospital discharge, or death, whichever occurred first. Indications for RBC transfusion included hemorrhage in 39 patients, improving oxygen-carrying capacity in 55, and hemolysis in 5. Results: Of the 99 transfused patients, 22 (22.22%) were also transfused after discharge from the ICU. Transfusions were more frequent in patients admitted with respiratory failure (30, 30.3%), hemorrhagic shock (24, 24.2%), and septic shock (18, 18.4%). The mean pretransfusion hemoglobin in ICU transfusions was statistically different (70.9 ± 12.7 g/l) from transfusions after discharge (79.7 ± 9.4 g/l) (p < 0.001). Longer ICU stay was associated with more RBC units transfused per transfusion episode per patient (p < 0.001). The Sequential Organ Failure Assessment (SOFA) score was significantly associated with the number of RBC units transfused per patient (p = 0.006). Mortality was significantly associated with Acute Physiology and Chronic Health Evaluation II and SOFA scores, the need and duration for mechanical ventilation, and the length of stay in hospital. Conclusion: Intensivists in our center followed a restrictive transfusion practice, by adopting a low pretransfusion hemoglobin threshold. Decisions on RBC transfusions seemed in most cases to be based on a ‘transfusion trigger’ rather than a physiologic need.

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Section: Discussioncontrasting

confidence: 53%

Blood Transfusion Practice in Critically Ill Patients: A Single Institutional Experience

Al-Faris¹,

Al-Fares

Malek

et al. 2012

Med Princ Pract

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“…In our study 56.9% of the transfused units were packed red cells, 22.7% fresh frozen plasma and 20.4% platelet concentrates. Similarly Rao et al, [10] assessed transfusion practice in 1,247 critically ill patients and showed that 53% were administered red cells, 22% fresh frozen plasma and 16% platelets.…”

Section: Discussionmentioning

confidence: 99%

Acute Transfusion Reactions (ATRs) in Intensive Care Unit (ICU): A Retrospective Study

Kumar

Gupta

et al. 2014

JCDR

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“…Bu konuyla ilgili pek çok çalışma bildirilmiştir (14)(15)(16)(17)(18)(19)(20)(21)(22) Bilindiği gibi dokulara oksijen sunumu; Hb konsantrasyonu, Hb değerinin saturasyon yüzdesi ve kalp debisine bağlıdır. Oksijen sunumundaki düşüş; dokudaki oksidatif metabolizmayı engeller ve anaerobik metabolizmaya kaymaya neden olur.…”

Section: Discussionunclassified

Uludag University Medical Faculty Research Hospital Emergency Service an Epidemiological Investigation into Blood and Blood Product Transfusion

Esen¹,

Aydın²,

Özdemir³

et al. 2012

JAEM

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Objective: This study was designed prospectively to investigate the demographic data of patients (n=434) who received blood and blood products at the Uludag University Medical Faculty Research Hospital Emergency Service between June 2009 and December 2009. The indications for the blood products used, the amount and the type of products used and the documentation of reactions were investigated and compared with data in the literature. Materials and Methods: 83.0% patients had normal vital parameters, 3.4% had hypotension, 2.1% had tachycardia, 1.1% had fever, 9.7% had hypotension and tachycardia and 0.7% had hypotension, tachycardia and fever. In terms of hemoglobin levels, 40.6% of patients had a level below 7 g/dL, 13.1% were between 7-8 g/dL, 26.7% were between 8-10 g/dL and 19.6% were above 10 g/dL. The patients who were transfused with an erythrocyte suspension were mostly the group who had a hemoglobin level below 7 g/ dL. Platelets were transfused mostly for thrombocytopenia in patients with a platelet count between 10-20 x 10 3 /mm 3 . Results:Of all transfused patients, 3.9% had an acute complication related to transfusion. 1.2% of these were acute febrile non-hemolytic reactions (FNHR), 1.1% were heart failure, 0.9% were allergic reactions and 0.7% were both FNHR and allergic reactions. 76.5% of all transfused patients were discharged from the emergency department, 19.4% were hospitalized, 2.5% were sent to other hospitals and 1.6% died in the emergency department. Conclusion: In light of our findings, it can be seen that many transfusions are performed in the emergency department, transfusion protocols are not normally followed and most transfusions are performed to support the outpatient clinic. (JAEM 2012; 11: 61-7)

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Blood component use in critically ill patients

Cited by 104 publications

References 18 publications

Blood Transfusion Practice in Critically Ill Patients: A Single Institutional Experience

Blood Transfusion Practice in Critically Ill Patients: A Single Institutional Experience

Acute Transfusion Reactions (ATRs) in Intensive Care Unit (ICU): A Retrospective Study

Uludag University Medical Faculty Research Hospital Emergency Service an Epidemiological Investigation into Blood and Blood Product Transfusion

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