Blood glucose level of white rats (<i>Rattus norvegicus</i>) after giving catfish biscuit (<i>Pangasius hypothalmus</i>)

Hidayaturrahmah,; Santoso, Heri Budi; Rahmi, Ridha Aulia; Kartikasari, Dewi

doi:10.1051/bioconf/20202004005

Cited by 13 publications

(11 citation statements)

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“…The hyperinsulinemic and hyperglycemic parameters showed the insulin resistance condition of the animal. In normal condition, rat fasting serum insulin level is <25 mIU/L and for blood glucose normal level is 50 -135 mg/dL (Hidayaturrahmah et al, 2020). Figures 2 showed increased the level of insulin and blood glucose level after administration of hyperchaloric diet for 16 weeks.…”

Section: Resultsmentioning

confidence: 94%

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Iqbal¹,

Saputri²,

Mun’im³

et al. 2023

J. Sci. n.a

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Section: Resultsmentioning

confidence: 94%

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Iqbal¹,

Saputri²,

Mun’im³

et al. 2023

J. Sci. n.a

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“…The measurement of malondialdehyde is not only through plasma and serum, but also from various tissues in kidney tissues in patients with diabetes. 9 According to Hidayaturrahmah et al (2020) 43 blood glucose levels in normal rats ranged from 50-135 mg/dl. 43 In Table 1, it can be seen that the average levels of blood glucose on the day 0 for all treatments were in normal rates, 66.29-68.40 mg/dl.…”

Section: Resultsmentioning

confidence: 99%

“…9 According to Hidayaturrahmah et al (2020) 43 blood glucose levels in normal rats ranged from 50-135 mg/dl. 43 In Table 1, it can be seen that the average levels of blood glucose on the day 0 for all treatments were in normal rates, 66.29-68.40 mg/dl. Similarly, in the same table, it was also shown that blood glucose levels in the experimental rats in the normal control on the measurement day 0, 3, and 18 were in normal rates; these groups shown to imply that all animal models were not diabetic without STZ-NA induction.…”

Section: Resultsmentioning

confidence: 99%

Antidiabetic Activity of the Leaf Extract of Eurycoma Longifolia Jack. in Streptozotocin-Nicotinamide Induced Diabetic Model

Panjaitan¹,

Astuti²

2021

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Background: One of the medication attempts in diabetes mellitus is by utilising plants that are potent as an antioxidant. Eurycoma longifolia Jack. known as "Longjack" in English, is a medicinal plant and reportedly effective as an antioxidant. Objectives: This study was aimed to examine the antidiabetic effectiveness of ethanol extract of longjack leaf in diabetes mellitus rats. Methods: This study used the total of 24 male white rats which were grouped into four. The normal and the negative control groups were administrated with CMC-Na 0.5% dose 2 ml/200 g body weight; one group was administrated with ethanol extract of longjack leaf dose 176.4 mg/200 g body weight; and the positive control group was administrated with glibenclamide dose 0.09 mg/200 g body weight. Before the extract administration, all of the experimental animals were prior induced into diabetic condition with streptozotocin-nicotinamide. Results: The levels of blood glucose and malondialdehyde in rats after the 14-day extract treatments were 78.73 mg/dl and 1.13 nmol/ml, respectively in the normal control group; 285.84 mg/dl and 10.03 nmol/ml were in the negative control group; 156.77 mg/dl and 3.86 nmol/ml in the group with the administration of ethanol extract of longjack leaf; and 148.63 mg/dl dan 3.64 nmol/ml in the group of glibenclamide administration (p<0.05). The reduction of blood glucose and malondialdehyde levels in the groups of ethanol extract administration of longjack leaf dose 176.4 mg/200 g body weight was similar to the glibenclamide administration dose 0.09 mg/200 g body weight. Conclusion: The ethanol extract of longjack leaf was effective as an antidiabetic.

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“…The normal blood glucose level in rats is 50-135mg/dL [41]. The results of the effect of sardine sh oil and njansan oil on the serum blood glucose level of obese Wistar rats are shown in Fig.…”

Section: Effect Of Sardine Sh Oil and Njansan Oil On Serum Blood Gluc...mentioning

confidence: 94%

Oral supplementation of njansan (Ricinodendron heudelotii Bail) and sardine fillets (Sardina pilchardus) oils alleviate high-fat diet-induced obesity in rats by regulating lipid metabolism and stress oxidative parameters

Florent,

Horliane,

Richard

2023

Preprint

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Background Obesity has become one of the most common metabolic disorders in the world, characterized by the accumulation of excess fat in the body. Research for natural compounds to improve obesity has become increasingly important. This study aims to explore the effects of Sardina pilchardus and Ricinodendron heudelotii oils on the management of obesity. Njansan (R. heudelotii) oil was extracted by cold pressing using an automatic oil press machine and sardine fish oil by a cooking method. To evaluate the anti-obesity effect of these oils, 6 groups of 6 male Wistar rats were fed different diets: C0 group received a normal diet; HFD was fed a high-fat diet; N1, N2, F1and F2 followed by a high-fat diet supplemented with njansan and sardine oils at 1g/kg body weight/day and 2g/kg body weight/day, respectively. Results It appears that regardless of the type of oil, the acid and peroxide values meet the standards prescribed by the Codex Alimentarius. There was an increase in body weight, relative abdominal fat, and liver weight in the HFD group compared to the control group. There was also a decrease in anthropometric parameters such as the Lee index of the HFD group treated with njansan and fish oils, regardless of the concentration. The hyperlipidemic state in the HFD-fed rats was then normalized after treatment with both oils as well as hyperglycemia compared to the control group. Besides, fish and njansan oils attenuated HFD-induced oxidative stress, as indicated by a significant increase CA and SOD. Conclusion This study demonstrated that njansan and sardine oils at a low daily dose (1g/kg body weight) can be helpful in managing obesity and also reduce the risk of developing coronary heart diseases.

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Blood glucose level of white rats (Rattus norvegicus) after giving catfish biscuit (Pangasius hypothalmus)

Cited by 13 publications

References 0 publications

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Antidiabetic Activity of the Leaf Extract of Eurycoma Longifolia Jack. in Streptozotocin-Nicotinamide Induced Diabetic Model

Oral supplementation of njansan (Ricinodendron heudelotii Bail) and sardine fillets (Sardina pilchardus) oils alleviate high-fat diet-induced obesity in rats by regulating lipid metabolism and stress oxidative parameters

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