Blood Groups of the Thais

Abstract

Blood and saliva from 456 unselected blood donom from the Shiraj Hospital, Bangkok were studied. The frequenaes of the ABO and Rh group closely resemble previous reports but A2and Cw were seen. The high frequency of M (67.87 per cent) and the low concentration of S (8.33 per cent) make MS and NS fairly uncommon. The frequeacy of 14.54 per cent for PI resembles the 6 g w for New York Chinese. Evidence for the presence of Jk was found in three of the 15 families studied but no Jk(a-b-) phenotypes were encountered. The 30.9 per cent frequency of Le(a+b-) and the 40.05 per cent frequency of Sc were unexpected, aa was the presence of aberrant secretors of ABH. Others findings include 1.19 per cent Mi(a+); 0.94 per cent Mt (a+); 0.44 per cent Lu(a-b-); l.!X per cent Ve(a-); 2.33 per cent Di(a+) and 13.48 per cent -(a+).LIMITED studies of the blood groups of the Thai people have been published previously. [13][14][15]18 The present study was planned to be more extensive in the hope of revealing facts previously unknown. The polymorphisms investigated were so numerous that a subdivision of labor was necessary. Portions of each blood sample received were sent to Dr. Eloise R. Giblett in Seattle for identification of transferrin, haptoglobin and Gc types and selected red cell enzyme variants; to Dr. Arthur G. Steinberg in Cleveland for establishing the Gm and Inv groups; to Dr. Nancy Simpson in Kingston, Ontario for testing for cholinesterase variants; and to Dr. Sergio de Lamerens of Milwaukee for hemoglobin electrophoresis. These studies will be reported when completed. The purpose of this re-Supported in part by

Investigation of Lewis Phenotypes in Polynesians: Evidence of a Weak Secretor Phenotype

“…The un usual finding of Le(a-l-b-) secretors of A and or B sub stance and Le(a-b-) secretors of salivary Le" substance has been reported in Thais [19]. Unfortunately, the Thai saliva was not tested for Leb activity and anti-LebH was used for the red cell phenotyping.…”

Studies on Anti-Mi^a and the MiIII Complex

“…When MNSs groups of Miltenberger-positive persons found in Thailand and their relatives were determined [1,3] it was noticed that some Milll cells reacted weakly with anti-N (rabbit) but not as strongly as MN, Mi(a -) and NN, Mi(a-) controls. Further studies on these 'weak N' cells were performed.…”

A Quantitative Study of Le^a, A and H Antigens in Salivas of Australian Caucasians and Aborigines

“…However, exceptions have been noted. Recently reported exceptions include a Japanese family where the parents and one child are secretors of A but not H antigen, and whose red cells group as A1( Le(a + b + ) [ 14]; 11 out of 134 Thais who secrete A or B but not H antigens, and whose cells group as Le(a + b-) [6]; 16% of 355 Australian Aborigines who secrete A and/or H and whose red cells group as Le(a + ) [22], Further indications that an appreciable proportion of Australian Abori gines who are secretors (and most of them are) have red cells which react with anti-Lea, can be seen in the collection of reports of Lewis-typings of red cells, compared with the reports of the frequencies of non-secretors among Aborigines .compiled by Kirk [12]. Some series of tests have shown up to 10-15% of Le(a + ) Aborigines, whereas the frequency of non-secretors has been reported as being about 2% [12,21,22].…”