Bone response to surface-modified titanium implants: studies on the early tissue response to machined and electropolished implants with different oxide thicknesses

Larsson, Christer; Thomsen, Peter; Aronsson, B.‐O.; Rodahl, Michael; Lausmaa, Jukka; Kasemo, Bengt Herbert; Ericson, Lars

doi:10.1016/0142-9612(96)88711-4

Cited by 344 publications

(266 citation statements)

References 33 publications

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“…In other words, the types and conditions of cells in the osteoblast lineage may affect proliferation responses to surface roughness. Larsson et al 36) reported that machined and electropolished implants with different oxide thicknesses had no clear influences on early tissue response. This finding was compatible with our result that there were no clear differences between A60 and A60VF in cell morphology and proliferation.…”

Section: Discussionmentioning

confidence: 99%

Surface Properties and Biocompatibility of Acid-etched Titanium

et al. 2008

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The purpose of this study was to evaluate the effects of acid-etched titanium on the biological responses of osteoblast-like MC3T3-E1 cells. Four types of treatments (polishing, sandblasting, concentrated H2SO4 etching, and concentrated H2SO4 etching with vacuum firing) were carried out on the surfaces of commercially pure titanium (cpTi) disks. MC3T3-E1 cells were then cultured on the treated cpTi surfaces. Through surface roughness measurement and SEM analysis, it was found that the acid-etched surfaces showed higher roughness values than the sandblasted ones. Scanning electron microscope analysis showed that the cells on the disks treated with acid-etching and acid-etching with vacuum firing spread as well as the sandblasted ones. There were no significant differences in cell proliferation and collagen production on cpTi among the four different surface treatments. Based on the results of this study, it was concluded that etching with concentrated sulfuric acid was a simple and effective way to roughen the surface of titanium without compromising its biocompatibility.

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Section: Discussionmentioning

confidence: 99%

Surface Properties and Biocompatibility of Acid-etched Titanium

et al. 2008

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“…Thus, it seems that a combination of surface topography and thick oxide present on the electro polished plus anodized implant surfaces are the most encouraging type of surface roughness for bone growth and the rapid healing of interfacial tissues. 48 …”

Section: Electro Polished and Anodized Implantsmentioning

confidence: 99%

A review of the surface modifications of titanium alloys for biomedical applications

Manjaiah¹,

Laubscher²

2017

Mater. tehnol.

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Dental implants are mechanical components that are used to restore the mastication (chewing) function and/or aesthetic appeal because of tooth loss or degradation. They are affixed (screwed) into the upper or lower jaw and act as a base for single or bridge-type tooth replacements. They are mostly manufactured from titanium alloys. The surface integrity of the manufactured implant may have a significant effect on the functioning and success of the implant. A systematic review is described on the effect of engineered surface integrity on the performance of titanium dental implants as regards the implant fixation, mechanical performance, bone growth and cell response. The need for surface engineering of the implant is introduced first. This includes the mechanical, surface-integrity and biocompatibility-required properties. This is followed by introducing and discussing the dedicated surface-modification processes currently employed. These include: abrasive blasting, electrochemical processes, hybrid processes and laser modification. The mechanical and biocompatible properties of an implant are the most crucial factor for their application in biomedical use. Hence, the present review article focused on the latest improvements to dental implant design based on the mechanical and biocompatible properties. The physical contact of an implant with respect to its surface roughness is an important factor in dental implant design. The surface roughness of an implant on the macro, micro and nano scales have specific effects on the implant's contact with the surrounding tissue of the bone. In addition, the biocompitability of titanium material is very important to develop a sustainable dental implant. Looking into the importance of the above mechanical and biocompatible properties of bone implants, the authors review elaborately the development of titanium-based implants with reference to the above properties. Keywords: implants, titanium, surface roughness, systematic review, surface engineering process, hybrid process, mechanical machining, chemical treatment Zobni vsadki so mehanske komponente, ki se jih uporablja za obnovo funkcije`ve~enja in/ali iz estetskih razlogov zaradi izgube ali poslab{anja zoba. Pritrjeni (privija~eni) so v zgornjo ali v spodnjo~eljust in slu`ijo kot osnova za nadomestni zob ali za mosti~ek. Ve~inoma so izdelani iz titanovih zlitin. Integriteta povr{ine izdelanih vsadkov lahko pomembno vpliva na delovanje in uspe{nost vsadka. Opisan je sistemati~en pregled o vplivu in`enirske celovitosti povr{ine na zmogljivost titanovega dentalnega vsadka glede na pritrditev vsadka, mehanske zmogljivosti, vra{~anja kosti in odziva celic. Najprej je predstavljena potreba po obdelavi povr{ine vsadka. To vklju~uje zahtevane mehanske lastnosti, celovitost povr{ine in biokompatibilnost. Temu sledi predstavitev in razlaga trenutno uporabljanih postopkov za namensko spremembo povr{ine. To vklju~uje: abrazivno peskanje, elektrokemijske procese, hibridne procese in modifikacijo z laserjem. Mehanske in biokompatibilne la...

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“…Higher osseointegration of anodic oxidized implants is observed during the initial healing period 1,2 because osteoblasts more easily attach to a rough surface than a smooth surface. 3,4 The quantity of calcium and phosphorus in the surface of the anodized oxide implant is greater than that of machined surface implants. 5,6 Additionally, differences in porosity allow for potential drug incorporation and release around titanium implants.…”

Section: Introductionmentioning

confidence: 99%

Surface changes of anodic oxidized orthodontic titanium miniscrew

Choi

Yul

Joo³

et al. 2012

The Angle Orthodontist

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Objective: To evaluate the structural stability of anodic oxidation treatment of miniscrews during a self-drilling procedure and an initial loading period. Materials and Methods: Eight orthodontic miniscrews with a machined surface and an anodic oxidized surface were placed in the mandible of two beagle dogs. With all miniscrews, an orthodontic force was applied immediately after placement and was continued for 12 weeks. After beagle dogs were sacrificed, the miniscrews were carefully removed from decalcified bone fragments. Miniscrews were evaluated by comparing and quantitatively analyzing changes in surface roughness of unused and used miniscrews (machined surface vs anodic oxidized surface) utilizing both scanning electron microscopy (SEM) and atomic force microscopy (AFM). Results: SEM revealed that only a thread edge close to the tip of the used anodic oxidized miniscrew became smooth by smearing, compared with the unused anodic oxidized miniscrew. No definite changes were observed in the thread valleys of the two groups after placement. AFM measurements demonstrated that all surface roughness parameters of thread edges of the used anodic oxidized miniscrews were significantly reduced compared with the unused anodic oxidized miniscrew (P , .05). A middle thread edge of the used anodic miniscrew surface was rougher than the unused and used machined surface miniscrews (P , .05). Conclusion: Anodic oxidized miniscrews had improved surface characteristics compared with machined surface miniscrews, even if the surface texture was changed by the self-drilling procedure and during the initial loading period. (Angle Orthod. 2012;82:522-528.)

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Bone response to surface-modified titanium implants: studies on the early tissue response to machined and electropolished implants with different oxide thicknesses

Cited by 344 publications

References 33 publications

Surface Properties and Biocompatibility of Acid-etched Titanium

Surface Properties and Biocompatibility of Acid-etched Titanium

A review of the surface modifications of titanium alloys for biomedical applications

Surface changes of anodic oxidized orthodontic titanium miniscrew

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