Bone Xenografts in Trauma and Orthopaedics (Analytical Review)

Stogov, M. V.; Смоленцев, Д. В.; Kireeva, E. A.

doi:10.21823/2311-2905-2020-26-1-181-189

Cited by 3 publications

(1 citation statement)

References 61 publications

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“…A new haptic surgical simulator for cerebral aneurysms was developed, and its role in neurosurgical residency training was evaluated [ 6 ]. Stogov et al say that surgical treatment of cerebral aneurysms is complex and rare and that a simulation-based tool is needed to educate future neurosurgeons to operate on cerebral arteries [ 7 ]. The simulator is a virtual reality aneurysm surgery simulator based on real-time haptic feedback.…”

Section: Literature Reviewmentioning

confidence: 99%

Application of Digital Orthopedic Technology in Orthopedic Trauma

Lin

Gong

et al. 2022

Computational and Mathematical Methods in Medicine

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In order to solve the limitation of auxiliary treatment means in the process of orthopedic trauma surgery, and further improve the effective integration of orthopedic trauma clinical surgery and computer technology, a new orthopedic trauma auxiliary treatment means based on digital orthopedic technology was proposed with the aid of virtual digital technology. The method builds a 3D model of fracture fragments through 3D orthopedic modeling and obtains a high-quality 3D model through processing. Later clinical tests verify the feasibility of this auxiliary treatment method. The test results show that the precision of the 3D reconstruction model based on custom option fitting is higher than that based on optimal option fitting, and the precision difference is within 0.2%. This result also indicates that the 3D model obtained by 3D reconstruction has higher accuracy. The results show that three-dimensional finite element modeling technology can accurately simulate the stress of the spine of orthopedic patients and can reduce the incidence of complications through preoperative diagnosis, curative effect prediction, and trauma surgery, which has a good aid for postoperative recovery.

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Section: Literature Reviewmentioning

confidence: 99%

Application of Digital Orthopedic Technology in Orthopedic Trauma

Lin

Gong

et al. 2022

Computational and Mathematical Methods in Medicine

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Evaluation of Biocompatibility of New Osteoplastic Xenomaterials Containing Zoledronic Acid and Strontium Ranelate

Stogov

Дюрягина

Силантьева

et al. 2023

Traumatology and Orthopedics of Russia

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Improving the biological and functional characteristics of implantable products and materials used in traumatology and orthopedics is a topical issue. Purpose Evaluation of the biocompatibility of osteoplastic xenomaterials containing zoledronic acid and strontium ranelate. Material and methods The study was carried out on 24 male rabbits. Tested bone blocks were implanted into the cavity of femoral defects. Group 1 (n=8, control) were implanted with xenogenic bone material "Osteoplastic Matrix "Bio-Ost"". Group 2 (n=8) were implanted with bone xenogenic material impregnated with zoledronic acid. Group 3 (n=8) were implanted with xenogenic bone material impregnated with strontium ranelate. Biocompatibility was assessed using X-ray, pathomorphological, histological and laboratory methods. The follow-up period was 182 days. Results. On the 182nd day after implantation, the area of newly formed bone tissue in the defect in group 1 was 79% by median, in group 2 - 0%, in group 3 - 67%. In group 2, by this time, the maximum area was occupied by connective tissue - 77%. The relative area of fragments of the implanted material on the 182nd day in group 1 was 4% by median, in group 2 - 23%, in group 3 - 15%. In animals of all groups, no rejection of the material was noted. Signs of intoxication, inflammatory or immune reactions were not observed. There was no infection of the material. Laboratory parameters did not change significantly. In group 1, two animals had a slight migration of the implanted material under the skin, one developed arthritis of the knee joint. In all groups, one of the animals noted increase in the level of C-reactive protein on the background of leukocytosis. Conclusion Osteoplastic materials based on bovine xenomatrix saturated with zoledronic acid and strontium ranelate have acceptable biocompatibility values, including safety indicators.

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The first clinical experience of using bone chips to promote sternum reossification after median sternotomy

Кузнецов

Шипулин

Лелик

et al. 2021

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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Федеральное государственное бюджетное научное учреждение «Томский национальный исследовательский медицинский центр» Российской академии наук, г. Томск, Россия Поступила в редакцию 06.07.2020 г.; принята к печати 01.12.2021 г.ЦЕЛЬ. Оценить первый опыт применения костной крошки при металлоостеосинтезе грудины в отношении безопасности и клинической эффективности. МЕТОДЫ И МАТЕРИАЛЫ. В исследование были включены 20 пациентов, по 10 человек в каждой группе (11 мужчин и 9 женщин; средний возраст в 1-й группе -(74,2±5,3) года; во 2-й -(72,4±6,7) года). Пациентам из 1-й группы в соответствии с целью исследования на этапе ушивания грудины имплантировали в губчатое вещество костную крошку. Во 2-ю группу вошли пациенты, которым оперативное лечение проводили по общепринятому, стандартному протоколу: губчатая ткань грудины обрабатывалась костным воском. РЕЗУЛЬТАТЫ. Оценку репарации грудины выполняли по данным спиральной компьютерной томографии. Исследовали исходное состояние костной ткани до выполнения операции, в раннем послеоперационном периоде (12-е сутки) и в среднесрочном периоде (через 12 месяцев после операции). Результаты оценивали по балльной шкале: 0 балловдиастаз более 3 мм, 12 баллов -полная консолидация грудины на всем протяжении. В раннем послеоперационном периоде степень сращения грудины в обеих группах не различалась (1-я группа -(3,5±0,7); 2-я группа -(3,5±0,8) балла). В среднесрочном периоде наблюдения (12 месяцев) степень сращения грудины у пациентов 1-й группы составила (11±0,7) балла, что практически в 2 раза больше, чем у пациентов второй группы, -(5,6±3) балла. ЗАКЛЮЧЕНИЕ. Применение ксеноматериалов для костной пластики у пациентов группы высокого риска сниженной репарации костной ткани после срединной стернотомии безопасно и эффективно.

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Bone Xenografts in Trauma and Orthopaedics (Analytical Review)

Cited by 3 publications

References 61 publications

Application of Digital Orthopedic Technology in Orthopedic Trauma

Application of Digital Orthopedic Technology in Orthopedic Trauma

Evaluation of Biocompatibility of New Osteoplastic Xenomaterials Containing Zoledronic Acid and Strontium Ranelate

The first clinical experience of using bone chips to promote sternum reossification after median sternotomy

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