Mobile Network Operators (MNOs) are in process of overlaying their conventional macro cellular networks with shorter range cells such as outdoor pico cells. The resultant increase in network complexity creates substantial overhead in terms of operating expenses, time, and labor for their planning and management. Artificial intelligence (AI) offers the potential for MNOs to operate their networks in a more organic and cost-efficient manner. We argue that deploying AI in 5G and Beyond will require surmounting significant technical barriers in terms of robustness, performance, and complexity. We outline future research directions, identify top 5 challenges, and present a possible roadmap to realize the vision of AIenabled cellular networks for Beyond-5G and 6G.