Brain tumors in early infancy—probably congenital in origin

Raskind, R; Beigel, Frieda

doi:10.1016/s0022-3476(64)80157-8

Cited by 28 publications

(9 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Only 4 cases had sur vived for more than 1 year. They are the cases of Ingraham and Bailey [29], M atson [44], R askind and Beigel [54] and the authors' respective lyInternal hydrocephalus associated with tumor in 4 of our 5 cases was responsible for the sudden deterioration of general condition. Therefore, shunting procedures such as continuous ventricular drainage [63] and VP shunt should be performed as first aid.…”

Section: Discussionmentioning

confidence: 60%

See 1 more Smart Citation

Brain Tumor in Newborn Babies

Takaku¹,

Kodama²,

Ohara³

et al. 1978

Pediatr Neurosurg

View full text Add to dashboard Cite

5 cases of brain tumor in newborn babies under 2 months are presented. 4 of them were supratentorial teratoma and originated from the midline, and 1 was a glioma at the cerebellopontine angle. 2 cases died before surgery and 2 cases after surgery. In our 5th case a benign teratoma of 150 g was removed from the third ventricle. He was discharged and enjoyed rather good health for 2 years and 1 month before dying of recurrence of tumor. Internal hydrocephalus associated with the huge tumor was responsible for the sudden deterioration of general condition. Therefore, shunting procedures should be performed as the first aid. However, in our experiences, the conditions at admission were too critical and/or too late to be beneficial. Thus, early diagnosis is absolutely necessary for surgical treatment. A summary and discussion of the data of 103 previously reported cases are included.

show abstract

Section: Discussionmentioning

confidence: 60%

“…It is noteworthy that 28 out of 103 cases were stillborn babies hav ing no opportunity for treatment. There are only 14 cases [4,23,29,36,44,52,54,55,62] including our 3 cases, in which craniotomy for remov al of tumors was carried out. 6 cases out of these 14 received total remov al, 6 partial removal and 2 biopsy (table IV).…”

Section: Discussionmentioning

confidence: 99%

Brain Tumor in Newborn Babies

Takaku¹,

Kodama²,

Ohara³

et al. 1978

Pediatr Neurosurg

View full text Add to dashboard Cite

show abstract

“…Infants with meningeal sarcoma, despite microscopic evidence of malignancy, enjoy a longer survival after radical resection and postoperative radiation therapy. On the contrary, choroid plexus papilloma has the best overall prognosis [16,20,26], though 80% of our patients remained shunt-dependent. Astrocytomas, benign or malignant, of this age group, usually invade diffusely the cere brum, diencephalon, or brain stem, and are associated with a poor prog nosis.…”

Section: Discussionmentioning

confidence: 90%

“…11 chil dren with normal head size were found to have hydrocephalus. The most common signs were a full, bulging fontanelle and rapid increase in head circumference, expressive of a flexible skull and open sutures [9,26,31,32], Despite this increase in intracranial pressure (ICP) the incidence of papilledema (28%) was low. Other signs of increased ICP were vomiting, abducens palsy, lethargy, irritability.…”

Section: Signs and Symptoms (Table 11-iv)mentioning

confidence: 99%

Brain Tumors during the First Year of Life

Raimondi

Tomita²

1983

Pediatr Neurosurg

View full text Add to dashboard Cite

Among 341 childhood brain tumors treated at Northwestern University – Children’s Memorial Hospital during the years 1967–1980, there were 39 children (11%) who presented during the first year of life. Half of the total number of childhood choroid plexus papillomas, meningeal sarcomas and teratomas we treated occurred in this particular age group. Supratentorial tumors were more common than infratentorial, a rate of 1.8:1. Medulloblastoma and benign astrocytoma were the most common histological types. Hydrocephalus was present in 82% of the children and papilledema in 28%, so that progressive enlargement of head circumference was the most common reason for referral. For the 37 patients who underwent surgical removal or biopsy of the tumor, the 1-month mortality rate was 19% and the 1-, 3- and 5- year survival rates were 46, 30 and 22%, respectively. Whenever tolerated, roentgen therapy was given. Most of the 24 deaths occurred within 6 months of the time of diagnosis. 5 patients (1 each with malignant astrocytoma, medulloblastoma, meningeal sarcoma, and 2 with choroid plexus papilloma) are still alive 5 years later, without neurological or mental deficit, and with no sign of recurrence. There were three exceptions to Collin’s rule. Among the 15 survivors, 5 suffer mental retardation.

show abstract

“…42 By definition, tumors presenting within 2 or 6 months of birth are considered congenita1. [44][45][46] Clinically, congenital medulloblastoma, as well as examples occurring in neonates and children under 2 years of age, are given special consideration.…”

Section: Medulloblastoma In Neonatesmentioning

confidence: 99%

Topical Review Article: Medulloblastoma: I. Clinical, Diagnostic, and Therapeutic Overview

Tomlinson¹,

Scheithauer²,

Meyer³

et al. 1992

J Child Neurol

View full text Add to dashboard Cite

Medulloblastoma, the most common embryonal tumor of the central nervous system, affects both children and adults. It poses a significant therapeutic challenge in that age-dependent differences exist, not only in their pathobiology, but in the efficacy of chemotherapy and radiotherapy. This is particularly the case in very young children, whose still developing nervous system exhibits a low tolerance to radiotherapy. We review the epidemiology, clinical presentation, radiologic features, and current therapeutic concepts relative to this unique neoplasm. Efforts are made to highlight clinical controversies.

show abstract

Brain tumors in early infancy—probably congenital in origin

Cited by 28 publications

References 4 publications

Brain Tumor in Newborn Babies

Brain Tumor in Newborn Babies

Brain Tumors during the First Year of Life

Topical Review Article: Medulloblastoma: I. Clinical, Diagnostic, and Therapeutic Overview

Contact Info

Product

Resources

About