Broadband ultrasound attenuation: a new diagnostic method in osteoporosis.

Resch, Heinrich; Pietschmann, Péter; Bernecker, P.; Krexner, E.; Willvonseder, R

doi:10.2214/ajr.155.4.2119116

Cited by 57 publications

(18 citation statements)

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“…The device measures broadband ultrasound attenuation (BUA) in dB/MHz in an axial direction through the heel. The method has been described earlier in detail by our study group [12]. The precision of the method was determined by repeated measurements of a single individual to be at 1.1% coefficient of variation (CV).…”

Section: Methodsmentioning

confidence: 99%

Ultrasound and X-ray-Based Bone Densitometry in Patients with Anorexia Nervosa

Resch¹,

Newrkla²,

Grampp

et al. 2000

Calcif Tissue Int

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In 20 patients (mean age 23+/-5 years) with anorexia nervosa (AN), bone mass was evaluated by broadband ultrasound attenuation (BUA) of the calcaneus, peripheral quantitative computed tomography (pQCT) of the distal radius, and dual X-ray absorptiometry (DXA) of the lumbar spine and the hip. Compared with 20 age- and sex- matched healthy controls, patients with AN showed marked osteopenia at all measuring sites. Values of BUA (33.0+/-9 dB/MHz vs. 51.0+/-5.7 dB/MHz; P<0.0001) and of BMD of all regions of the hip (e.g., femoral neck: 0.71+/-0.13 g/cm(2) versus 0.89+/-0.07 g/cm(2); P<0.001), lumbar spine (0.82+/-0.15 g/cm(2) versus 1.24+/-0.06 g/cm(2); P<0.003) and total BMD of the peripheral radius (303.2+/-75 g/cm(3) versus 369.4+/-53.2 g/cm(3), P<0.001) were significantly reduced. Calculating a Z-score we found the most prominent differences between AN and controls by BUA of the calcaneus (-3.2+/-1.6), followed by DXA at the lumbar spine (-2.9+/-2.2) and the hip (femoral neck -2.1+/-1.7) and by pQCT at the distal radius (total BMD -1.2+/-2.0). There were highly significant correlations between BUA of the calcaneus and BMD of the femoral neck (r = 0.78, P<0.0001) and lumbar spine (r = 0.75, P<0.0001) as well as between BMD values of the femoral neck and lumbar spine (r = 0.95; P<0.0001). In addition, there were significant correlations (P<0.001) between body mass index (BMI) and the three different measuring sites and between the duration of the disease and BUA (r = 0.5, P<0.05). Our data suggest that BUA of the calcaneus is a valuable tool in the management of osteoporosis. Being a fast, radiation-free investigation method of good acceptance, it may be well suited for an assessment of the skeletal status in patients with AN.

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Section: Methodsmentioning

confidence: 99%

Ultrasound and X-ray-Based Bone Densitometry in Patients with Anorexia Nervosa

Resch¹,

Newrkla²,

Grampp

et al. 2000

Calcif Tissue Int

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show abstract

“…In previous studies, the short-term reproducibility of BUA measurements in vivo has varied from 2.9 to 4.6 percent (Resch et al 1990, Damilakis et al 1992, T N S C O~~ et al 1992, Herd et al 1992). The reproducibility obtained in our study (3.5 percent) was similar to that found in these previous reports.…”

Section: Discussionmentioning

confidence: 98%

Ultrasound attenuation of the calcaneus in normal subjects and in patients with wrist fracture

Kröger

Jurvelin

Amala

et al. 1995

Acta Orthopaedica Scandinavica

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“…111 Broadband ultrasound attenuation has been shown to be comparable to DXA in discriminating between normal individuals and those who have an osteoporotic fracture, and results correlate well with the vertebral and femoral neck density measured by DXA, SPA of the distal forearm, and QCT of the lumbar spine. [121][122][123][124] At the calcaneus there is a high correlation between QUS and DXA measurements (r = 0.8-0.85). 125 It has been shown that a decrease of SOS 1 standard deviation or more below normal resulted in a 3-to 5-fold increased risk for vertebral crush fractures in the following 2 years than those with normal results.…”

Section: -70mentioning

confidence: 98%