Buckwheat and CVD Risk Markers, a Systematic Review and Meta-Analysis

Li, Liangkui; Seal, Chris

doi:10.20944/preprints201803.0155.v1

Cited by 7 publications

(2 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In human, buckwheat intervention significantly reduced glucose metabolism (0.85 mmol/L, 95% CI[1.31, 0.39]), total cholesterol (0.50 mmol/L, 95% CI [0.80, 0.20]) and triglycerides (0.25 mmol/L, 95% CI [0.49, 0.02]), compared with the control group. However, only triglycerides and total cholesterol showed slight differences in animals, with high heterogeneity [55]. On the other hand, another trial on quinoa suggested that quinoa consumption Fig.…”

Section: Discussionmentioning

confidence: 96%

Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

Wang

Chen

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background: The effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet on cardiovascular risks in obese/overweight adults.Methods: PubMed, Embase and Cochrane were systematically scanned for randomized controlled trials (RCTs), and studies were selected based on certain inclusion and exclusion criteria. The primary outcome was the effectiveness of whole grain food consumption in reducing body weight. The secondary outcomes were the effect of whole grain food consumption on cardiovascular disease (CVD) risk factors including plasma low-density lipoprotein cholesterol (LDL-C), insulin resistance index, blood pressure, body mass index (BMI), C-reactive protein (CRP), and waist circumference in obese/overweight adults.Results: Our results showed that whole grain consumption was associated with lower body weight (mean difference (MD) = − 0.5, 95% confidence intervals (CI) [− 0.74, 0.25], I 2 = 35%, P < 0.0001) and lower CRP (MD = -0.36, 95% CI [− 0.54, − 0.18], I 2 = 69%, P < 0.0001), compared with the control group. However, there were no significant differences in LDL-C (MD = -0.08, 95% CI [− 0.16, 0.00], I 2 = 27%, P = 0.05), waist circumference (MD = -0.12, 95% CI [− 0.92, 0.68], I 2 = 44%, P = 0.76), systolic blood pressure (MD = -0.11, 95% CI [− 1.55, 1.33], I 2 = 3%, P = 0.88), diastolic blood pressure (MD = -0.44, 95% CI [− 1.44, 0.57], I 2 = 15%, P = 0.39), and fasting glucose (MD = -0.05, 95% CI [− 0.12, 0.01], I 2 = 31%, P = 0.11) between the two groups. Conclusion: This study suggests that whole grain food consumption can slightly reduce body weight and CRP in obese/overweight population.

show abstract

Section: Discussionmentioning

confidence: 96%

Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

Wang

Chen

et al. 2020

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…In a metaanalysis, Liangkui Li group investigated the effect of buckwheat on improving CVD risk factors in both human and animals. In human, compared with control group, the glucose metabolism, total cholesterol and triglycerides were significantly improved following buckwheat intervention [40]. However, in another trial regarding quinoa conducted by Liangkui Li group, they suggested that quinoa consumption can regulate glucose response, while only has minimal effects on other CVD risk biomarkers [41].…”

Section: Discussionmentioning

confidence: 96%

The effect of a whole grain diet on reducing cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

Wang¹,

Li²,

Chen³

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Cardiovascular disease (CVD) remains the leading cause of mortality worldwide. Overweight, hypertension, and dyslipidemia are clinically recognized as the most significant cardiovascular risk conditions. Studies have shown that whole grains are beneficial to affect glucose metabolism, obesity, blood pressure, lipids and inflammatory markers. Methods: We did a research in PubMed, Embase and Cochrane for randomized controlled trials (RCTs) and selected the study according to the eligibility criteria and data extraction. Then we evaluate the effectiveness of whole grain foods on body weight (primary outcome) and other CVD risk factor indicators, including plasma low-density lipoprotein-cholesterol level, insulin resistance index, blood pressure, BMI, waist circumference (secondary outcome) in overweight/obese adults. Results: Our results showed that there are significant decrease of weight (P<0.0001, mean difference -0.5, 95% CI[-0.74, -0.25], I 2 =35%), LDL-C (P=0.05, mean difference -0.08, 95% CI[-0.16, 0.00], I 2 =27%), CRP (P<0.0001, mean difference -0.36, 95% CI[-0.54, -0.18], I 2 =69%) in whole grain group compared with control group (Fig 2-4). There are no significant difference in waist circumference (P=0.76, mean difference -0.12, 95% CI[-0.92,0.68], I 2 =44%), systolic blood pressure (P=0.88, mean difference -0.11, 95% CI[-1.55, 1.33], I 2 =3%), diastolic blood pressure (P=0.39, mean difference -0.44, 95% CI[-1.44, 0.57], I 2 =15%), fasting glucose (P=0.11, mean difference -0.05, 95% CI[-0.12, 0.01], I 2 =31%) between two groups. Conclusion: This study suggests whole grain food has only a moderate effect on reducing body weight, LDL-C and CRP in obese population, which is obviously showed in patients combined with other chronic metabolic disorders.

show abstract

A Crop of High Nutritional Quality and Health Maintenance Value: The Importance of Tartary Buckwheat Breeding

Kreft,

Golob,

Germ

2023

Agriculture

View full text Add to dashboard Cite

Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.), originating in the Himalayan area, is cultivated in central Asia and northern, central, and eastern Europe. Tartary buckwheat grain and sprouts are rich in flavonoid metabolites rutin and quercetin. The synthesis of flavonoids in plants is accelerated by UV-B solar radiation to protect the plants against radiation damage. During Tartary buckwheat food processing, a part of rutin is enzymatically converted to quercetin. Rutin and quercetin are able to pass the blood–brain barrier. Studies have investigated the effects of rutin and quercetin on blood flow to the brain, consequently bringing more nutrients and oxygen to the brain, and causing improved brain function. In addition to the impact on blood flow, rutin and quercetin have been shown to have antioxidative properties. The goals of breeding Tartary buckwheat are mainly to maintain and enhance the high nutritional quality. The goals could be reached via the breeding of Tartray buckwheat for larger cotyledons. Other main breeding efforts should be concentrated on the easy husking of the grain, the prevention of seed shattering, and the improvement in growth habits to obtain uniformity in grain ripening and a stable and high yield.

show abstract

Buckwheat and CVD Risk Markers, a Systematic Review and Meta-Analysis

Cited by 7 publications

References 72 publications

Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

The effect of a whole grain diet on reducing cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

A Crop of High Nutritional Quality and Health Maintenance Value: The Importance of Tartary Buckwheat Breeding

Contact Info

Product

Resources

About