Calcipotriol/betamethasone ointment compared to narrow‐band UVB in plaque psoriasis: first clinical and ultrasonographic study

Polańska, Adriana; Gaura, Tomasz; Bowszyc‐Dmochowska, Monika; Osmola‐Mańkowska, Agnieszka; Olek‐Hrab, Karolina; Adamski, Zygmunt; Żaba, Ryszard; Dańczak‐Pazdrowska, Aleksandra

doi:10.1111/ijd.14150

Cited by 13 publications

(11 citation statements)

References 32 publications

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“…Previous studies have reported SLEB as a typical ultrasonic characteristic in photoaging skin 8 . But with the application of HF‐US in more and more skin lesions, SLEB is not a specific ultrasonic feature and can be found in atopic dermatitis and MF, and is considered to be caused by edema or infiltration of inflammatory cells 3,6,7,9‐13 . The study of Polanska et al showed a significant correlation between the depth of lymphocytes infiltration in histopathology and thickness of SLEB in plaque psoriasis, 17 and the SLEB narrowed or disappeared after treatment, which showed the better correlation between the HF‐US and pathology.…”

Section: Discussionmentioning

confidence: 97%

“…The ultrasound characteristics of the lesions were independently evaluated by 2 senior sonographers, and they reached an agreement by discussion when the results were inconsistent. Based upon the previous reports, 1‐13 the assessment of the ultrasound images included evaluation of epidermal morphology (even or uneven), infiltration depth (the deepest layer of the skin that the lesion infiltrated), subepidermal low echogenic band (SLEB) boundary (clearly or unclearly identified from the underlying skin structures), SLEB internal echo (homogeneous or inhomogeneous), epidermis thickness (the vertical distances of the thickest parts of epidermis), SLEB thickness (the vertical distances of the thickest parts of SLEB) (Figures 2 and 3), and number of linear acoustic shadows behind the epidermis in the same section (the vertical low echogenic band behind the epidermis) (Figure 4).…”

Section: Methodsmentioning

confidence: 99%

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The value of high‐frequency ultrasonography in the differential diagnosis of early mycosis fungoides and inflammatory skin diseases: A case‐control study

Niu

Wang

Zhu

et al. 2020

Skin Research and Technology

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Background The clinical manifestations of early mycosis fungoides (eMF) are non‐specific and similar to inflammatory skin diseases. High‐frequency ultrasonography (HF‐US) can show small structure of skin lesions and is helpful to provide information objectively. Materials and Methods A case‐control study was designed in 62 patients with multiple erythemas and scales, including 18 eMF and 44 age‐matched patients with eczema (EC) or psoriasis vulgaris (PsV). The most significant lesions were collected by 50 MHz HF‐US. The assessment of ultrasound included epidermal morphology and thickness, infiltration depth, subepidermal low echogenic band (SLEB) boundary and thickness, internal echo, and number of linear acoustic shadows (LAS) behind the epidermis. The ultrasonic characteristics of eMF, EC, and PsV lesions were analyzed. Results Epidermal thickness (P < .001, sensitivity 88.9%, specificity 75.0%) and SLEB thickness (P = 0.006, sensitivity 55.6%, specificity 90.9%) were useful for differential diagnosis of eMF and PsV/EC. When eMF was diagnosed by epidermal thickness < 0.2375 mm, the AUC was 0.845, which had the highest diagnostic efficacy among all ultrasound signs. In addition, compared with eMF and EC, the LAS number of PsV lesions was the highest and statistically significant. Conclusion The results showed that HF‐US could provide some extra information in identification of eMF, EC, and PsV and has potential clinical value.

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Section: Discussionmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

The value of high‐frequency ultrasonography in the differential diagnosis of early mycosis fungoides and inflammatory skin diseases: A case‐control study

Niu

Wang

Zhu

et al. 2020

Skin Research and Technology

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“…Trichoscopy comes to the evaluation of the surface of the skin 12 . On the other hand, HF‐USG which has been widely used in dermatology for over 20 years, 15 mainly in dermatooncology, but it has also found an application in monitoring diseases such as psoriasis vulgaris, atopic dermatitis, skin lymphomas, morphea, and skin condition assessment radiotherapy 16‐22 There are individual studies presenting the use of HF‐USG in hair imaging 5‐7 . It is recognized that transducers using frequencies around 15 MHz are not sensitive enough to visualize individual structures such as sebaceous glands, sweat glands, and the arrector pili muscles, which require higher frequencies, that is, 29‐71 MHz 5 …”

Section: Discussionmentioning

confidence: 99%

High‐frequency ultrasonography of the scalp ‐ Comparison of ultrasound and trichoscopic images in healthy individuals

Mikiel

Polańska

Żaba

et al. 2020

Skin Research and Technology

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Background Hair loss is a common problem in dermatological patients. Its diagnosis is based on selected non‐invasive and invasive tests. Searching for new diagnostic methods, especially non‐invasive ones, aims to accelerate the correct diagnosis in the least invasive way possible. The aim of our study was to establish the characteristics of ultrasound images in healthy individuals and to compare them to selected trichoscopic parameters. Materials and methods Eighteen healthy adults (10 women and 8 men) underwent trichoscopy and high‐frequency ultrasound (HF‐USG) with 20 MHz DermaScan transducer on the parietal region of the scalp. Selected parameters were compared in relation to sex and the research method used. Results HF‐USG of the parietal area in all examined patients revealed hyperechogenic entrance echo and less echogenic layer corresponding to the dermis with well‐defined hypoechoic follicular structures (FS). The number of hair units in trichoscopy and the number of FS in HF‐USG did not differ significantly, while the differences in the studied distances between structures were statistically significant. The width of FS in HF‐USG was significantly higher than hair shafts thickness in trichoscopy. Conclusions HF‐USG (20MHz) due to the possibility of visualization of FS can be a valuable complement to the range of non‐invasive diagnostic procedures used in evaluation of the scalp.

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“…Finally, a recent study using 20-MHz HFUS to compare two treatment arms reliably demonstrated a reduction in the SLEB of psoriatic skin coinciding with clinical improvement, supporting the use of ultrasonography as a useful objective marker in patients with psoriasis [70].…”

Section: Psoriasismentioning

confidence: 78%

High-frequency ultrasound in clinical dermatology: a review

et al. 2021

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Background Ultrasound was first introduced in clinical dermatology in 1979. Since that time, ultrasound technology has continued to develop along with its popularity and utility. Main text summary Today, high-frequency ultrasound (HFUS), or ultrasound using a frequency of at least 10 megahertz (MHz), allows for high-resolution imaging of the skin from the stratum corneum to the deep fascia. This non-invasive and easy-to-interpret tool allows physicians to assess skin findings in real-time, enabling enhanced diagnostic, management, and surgical capabilities. In this review, we discuss how HFUS fits into the landscape of skin imaging. We provide a brief history of its introduction to dermatology, explain key principles of ultrasonography, and review its use in characterizing normal skin, common neoplasms of the skin, dermatologic diseases and cosmetic dermatology. Conclusion As frequency advancements in ultrasonography continue, the broad applications of this imaging modality will continue to grow. HFUS is a fast, safe and readily available tool that can aid in diagnosing, monitoring and treating dermatologic conditions by providing more objective assessment measures.

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Calcipotriol/betamethasone ointment compared to narrow‐band UVB in plaque psoriasis: first clinical and ultrasonographic study

Cited by 13 publications

References 32 publications

The value of high‐frequency ultrasonography in the differential diagnosis of early mycosis fungoides and inflammatory skin diseases: A case‐control study

The value of high‐frequency ultrasonography in the differential diagnosis of early mycosis fungoides and inflammatory skin diseases: A case‐control study

High‐frequency ultrasonography of the scalp ‐ Comparison of ultrasound and trichoscopic images in healthy individuals

High-frequency ultrasound in clinical dermatology: a review

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