Camellia sinensis (Tea): Implications and role in preventing dental decay

Goenka, Puneet; Sarawgi, Aditi; Karun, Vinayak; Nigam, Aruna; Dutta, Samir; Marwah, Nikhil

doi:10.4103/0973-7847.120515

Cited by 62 publications

(31 citation statements)

References 36 publications

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“…2 The recent investigation associated with the bioactive compound like polyphenols-flavonoids-catechins of tea due to their antioxidant activities which contribute to human health benefits. 3,4 Pharmacological research indicates that tea leaf extract has pharmacological activities such as antidiabetic, anticarcinogenic, antiviral, antibacterial, antiinflammatory, anti-aging and immune boosting antioxidant activities which contribute to human health. 1,[5][6][7] This activity associated with the efficacy of tea for the prevention and treatment of diasease.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Acute Oral Toxicity Study of White Tea Leaf (Camellia sinensis (L.) Kuntze) Ethanolic Extracts

Ardiana¹,

Ekayanti²,

Najib³

et al. 2017

Phcog J

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Background: White tea is a kind of tea which manufactured with minimal processing only drying without fermentation process. White tea prepared from very young tea leaves or buds of Camellia sinensis (L.) Kuntze, Theaceae, covered with tiny, silvery hairs, and dried immediately after picking to prevent oxidation and commonly used as a beverage and herbal medicine. Objective: The present study was aimed to evaluate the safety of the white tea leaf ethanolic extract (WTE) with acute toxicity tests. Methods: The acute oral toxicity of WTE performed at dose 1250, 2500, and 5000 mg/Kg BW of Deutschland, Denken, and Yoken (DDY) mice. The animals observation for any mortality, behavioral, body weight and feed-water consumption pattern during the 14-day study. The liver, kidney, and heart isolation performed on day-15 to observe macroscopic and relative organ weight (ROW). Results: No treatment-related toxic symptom or mortality observed for the first 4 hours and 24 hours after oral administration of WTE at a dose of 1250, 2500, and 5000 mg/kg BW. All the groups of mice did not show the significant changes in behavior, breathing, and motoric activity. Conclusions: This studies showed that the oral LD 50 of WTE was greater than 5000 mg/kg BW and suggests that the WTE is practically non-toxic in a single dose of level 5000 mg/kg BW. important to determine the potential acute toxicity of herbal medicines through LD 50 value and the spectrum of toxic effects. The potential acute toxicity of herbal medicine can be used to assess the limits of safety or therapeutic index (LD 50 / ED 50 ). The efficacy and toxicity of tea leave assumed from their very long history of consumption in the world and their main functional ingredients studies, 7 but a systematic evaluation of the toxicity of white tea has been lacking. Therefore, the present study was aimed to evaluate the safety of the white tea leaf ethanolic extract (WTE) with acute toxicity tests in Deutschland, Denken, and Yoken (DDY) mice. MATERIALS AND METHODS Plant Material and ExtractionThe white tea obtained from the Tea Plantation and Quinine Research Center in Gamboeng, West Java, Indonesia. White tea leaves (Camellia sinensis L. Kuntze) sorted and collected then dried under sunlight. Furthermore, the tea leaves withered with a dryer. The white tea leaves powder made by grinding dried white tea leaves by using a grinder. Extraction method conducted by reflux with ethanol 70% at 60 o C for 3 hours, then re-reflux for two times and evaporated using evaporator. Animal Test Statistical AnalysisStatistical analysis determined as mean value ± standard deviation (SD). The data with normal distribution analyzed with one-way ANOVA followed by multiple comparisons using Bonferroni test. However, abnormal distribution analyzed with Kruskal-Wallis test. Probability level of less than 5% (p < 0.05) was considered significant. RESULTSNo treatment-related toxic symptom or mortality observed for the first 4 h and 24 h after oral administration of WTE at a dose of 1250, 2500, and...

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Section: Introductionmentioning

confidence: 99%

Preliminary Acute Oral Toxicity Study of White Tea Leaf (Camellia sinensis (L.) Kuntze) Ethanolic Extracts

Ardiana¹,

Ekayanti²,

Najib³

et al. 2017

Phcog J

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“…Several studies with different methodologies have evaluated anticariogenic effects of green tea, and almost all of them reported the capacity of green tea to inhibit dental caries. Goenka et al 56 gums and evaluated the effects of chewing green tea gums on building tooth resistance to acid attacks. They concluded that chewing green tea gums increases the resistance of dentin to acid.…”

Section: Discussionmentioning

confidence: 99%

Effect of Green Tea Varnish on Depth of Root Caries

Daneshyar

Khamverdi

Toliat

et al. 2018

The Journal of Contemporary Dental Practice

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Aim: Root caries is a common, debilitating condition particularly in the elderly population, which can lead to tooth loss. Evidence shows that green tea has cariostatic effects. Considering the gap of information on green tea varnish, this study aimed to assess the efficacy of green tea varnish in the prevention of root caries. Materials and methods:This in vitro experimental study was performed on 42 sound premolars. Two layers of acid-resistant nail varnish were applied on root surfaces except for a window of 1 × 4 mm. The teeth were randomly divided into three groups (n = 14). Group I (control) received no intervention. Group II received green tea varnish applied on the roots every 48 hours for 21 days. Group III received green tea varnish every 24 hours for 21 days. Sections of 40 µ thickness were prepared from the center of the window, and the depth of carious lesion was measured in three points with 500 µ distance from each other using polarized light microscope. Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 16 and nonparametric Kruskal-Wallis and Mann-Whitney U tests (α = 0.05). Results:The mean (and standard deviation) depth of carious lesion was 54.30 ± 28.64 (µm), 0, and 0 in groups I, II, and III respectively. Control group showed the highest depth of caries. Groups II and III were not significantly different in this respect, but significant differences were noted in depth of caries between groups I and II and also groups I and III (p < 0.001). Clinical significance: Application of green tea varnish can prevent root caries. Conclusion

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“…GC, EGC and EGCG possess strong bactericidal as well as antibacterial activity. Certain studies have also shown an inhibitory effect of tea over the acid production by cariogenic bacteria thus imparting a caries protective action (Goenka, Sarawgi, Karun, Nigam, Dutta & Marwah, 2013).…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Green Tea Mouth Rinse over Combination Mouth Rinse in Restoring Salivary pH Post Sugar Exposure in Children

Singh¹

2020

JSR

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Dental caries is a multifactorial disease. The contents of green tea have been found beneficial in prevention of dental caries. This study compared the effect of green tea mouth rinse and combination mouth rinse on salivary pH post sugar exposure in children. 40 children (6-8years) were randomly selected. Study was conducted over a period of two days. Baseline pH of unstimulated saliva and salivary pH after rinsing with 50% sugar solution was recorded using digital pH-meter on both days. Subjects were asked to rinse with green tea mouthwash on Day 1 and with combination mouthwash on Day 2. Salivary pH was recorded 10 minutes after mouth rinse. The data was subjected to paired T-test. The mean salivary pH after green tea rinse was 7.16 ± 0.27 and after combination mouthwash was 6.61 ± 0.23. On comparing the data of green tea mouth rinse with combination mouth rinse, the difference was found to be statistically significant (p<0.001). Green tea was found more effective than combination mouth rinse in restoring the salivary pH post sugar exposure.

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Camellia sinensis (Tea): Implications and role in preventing dental decay

Cited by 62 publications

References 36 publications

Preliminary Acute Oral Toxicity Study of White Tea Leaf (Camellia sinensis (L.) Kuntze) Ethanolic Extracts

Preliminary Acute Oral Toxicity Study of White Tea Leaf (Camellia sinensis (L.) Kuntze) Ethanolic Extracts

Effect of Green Tea Varnish on Depth of Root Caries

Effectiveness of Green Tea Mouth Rinse over Combination Mouth Rinse in Restoring Salivary pH Post Sugar Exposure in Children

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