Campylobacter 0:41 isolation in Guillain-Barre syndrome

Goddard, E.; Lastovica, Albert J.; Argent, Andrew C.

doi:10.1136/adc.76.6.526

Cited by 50 publications

(37 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In South Africa, 9 (53%) of 17 children admitted to an intensive care unit with GBS had evidence of C. jejuni infection and all isolates were Penner serotype 0:41. This particular serotype was isolated from only 12 (including the nine GBS isolates) of 7119 isolates (Ͻ0.002%) of C. jejuni in that laboratory during the same time period, thus supporting a causal relationship between rare variants of this organism and GBS (117,118). Interestingly, these findings have not been reproduced in U.K. studies, implying that the GBS-inducing properties of C. jejuni may not be solely related to Penner serotype (110).…”

Section: Clinical Manifestationsmentioning

confidence: 96%

Enteric Campylobacter: Purging Its Secrets?

et al. 2004

View full text Add to dashboard Cite

Section: Clinical Manifestationsmentioning

confidence: 96%

Enteric Campylobacter: Purging Its Secrets?

et al. 2004

View full text Add to dashboard Cite

“…HS:2 was found to be over-represented in FS patients (present in 71% of the patients versus 38% of the controls), but only 7 isolates from FS patients were studied. In South Africa, 6 of 9 GBS isolates were HS:41; this serotype accounts for only 0.1% of enteritis strains (8). In contrast, in The Netherlands and Belgium only two isolates from 12 GBS patients were HS:19, and none were HS:41 (5).…”

Section: Vol 43 2005mentioning

confidence: 99%

Epidemiology ofCampylobacter jejuniIsolated from Patients with Guillain-Barré and Fisher Syndromes in Japan

et al. 2005

View full text Add to dashboard Cite

Campylobacter jejuni isolation is the standard for the diagnosis of this type of bacterial infection, but there have been no epidemiological studies of a large number of C. jejuni isolates from patients with Guillain-Barré syndrome (GBS) and Fisher syndrome (FS). For 13 years, stool specimens from GBS/FS patients have been sent from 378 hospitals throughout Japan to the Tokyo Metropolitan Institute of Public Health. A total of 113 strains (11%) were isolated from the stool specimens from 1,049 patients. The isolation rate did not differ by region. The rates were 22% for 449 patients with a history of diarrhea and 2% for the others. An additional 18 isolates were provided by various hospitals. There was no noticeable seasonal distribution in the onset of C. jejuni isolated from patients with GBS/FS. The male/female ratios were 1.7:1 for GBS and 2.2:1 for FS. The patient age range showed a peak in 10-to 30-year-old subjects who had GBS and in 10-to 20-year-old subjects who had FS. The predominance of young adults and male patients who had C. jejuni-associated GBS/FS may be related to the preponderance of young adults and male patients who had C. jejuni enteritis. The median interval from diarrhea onset to neurologic symptom onset was 10 days for GBS/FS. Penner's C. jejuni serotype HS:19 was more frequently present in GBS (67%) than in enteritis (6%) patients. HS:2 was more frequent in FS (41%) than in enteritis (14%) patients. These findings suggest that certain C. jejuni strains specifically trigger GBS and that others specifically trigger FS.

show abstract

“…There have also been rare/controversial reports of hemolytic-uremic syndrome and Guillain-Barré syndrome associated with C. upsaliensis (4,9,14). In both pediatric and immunocompromised hosts, C. upsaliensis is recognized as a clinically important emerging diarrheal pathogen (10,17,19).…”

mentioning

confidence: 99%

Association of Campylobacter upsaliensis with Persistent Bloody Diarrhea

2012

View full text Add to dashboard Cite

Campylobacter upsaliensis is a zoonotic, emerging pathogen that is not readily recovered in traditional stool culture. This case represents the first report of persistent bloody diarrhea with C. upsaliensis that was confirmed by filtration culture, PCR, and sequencing. CASE REPORTA n 83-year-old male presented to the emergency department (ED) with an acute history of severe bloody diarrhea. His symptoms began with nausea, vomiting, and abdominal cramping, which he mistook for constipation. The patient took a single dose of laxative and shortly thereafter experienced numerous episodes of profuse bloody diarrhea that continued for several hours. He did not have fevers, chills, or sweats. The patient was found by his wife at home, collapsed in a chair, and was brought to the ED for evaluation. The patient's past medical history was significant for irritable bowel syndrome but no history of bloody diarrhea or rectal bleeding. His social history revealed contact with his sisterin-law and two canine pets, all with bloody diarrhea. On arrival in the ED, the patient's physical examination was unremarkable; however, out of concern for a lower gastrointestinal bleed, the patient was admitted for observation and further testing. Stool studies were negative for all gastrointestinal pathogens, including Salmonella, Shigella, Campylobacter, Aeromonas, Plesiomonas, and Vibrio by stool culture, Cryptosporidium, Giardia, and Shiga-toxigenic Escherichia coli (STEC) by enzyme immunoassay (EIA), and Clostridium difficile by PCR. In addition, ovum and parasite exams of the stool were performed and were remarkable only for numerous erythrocytes and leukocytes. These findings were consistent with the grossly bloody stool and a positive fecal lactoferrin EIA. The patient's symptoms gradually improved but did not resolve over the course of 48 h. He remained afebrile and hemodynamically stable and was discharged on hospital day 2 with no known etiologic cause of diarrhea. Five days later, he was treated with ciprofloxacin for continuing diarrhea out of concern for possible person-to-person spread of a still-unidentified gastrointestinal pathogen but only after STEC was ruled out by Shiga toxin EIA.The clinical microbiology laboratory was consulted for additional testing for enteroinvasive or enteroaggregative E. coli, given the widely publicized enteroaggregative/Shiga-toxigenic E. coli O104:H4 outbreak that had recently concluded in Germany. No testing was available for these organisms; however, the stool was filtered through a 0.6-m filter (Pall Life Sciences, Ann Arbor, MI) onto a brucella blood agar plate (Hardy Diagnostics, Santa Maria, CA) and cultured in an increased-hydrogen atmosphere of approximately 6.5 to 12.5% (7) (BioBag Type Cfj; BD, Franklin Lakes, NJ) at 37°C to enhance the detection of hydrogen-requiring Campylobacter spp. (21). For direct stool PCR, the specimen was treated with AL stool lysis buffer (Qiagen, Valencia, CA) and heated at 95°C for 10 min. The DNA was extracted with the Maxwell Cell LEV DNA purification k...

show abstract

Campylobacter 0:41 isolation in Guillain-Barre syndrome

Abstract: (Arch Dis Child 1997;76:526-528)

Cited by 50 publications

References 26 publications

Enteric Campylobacter: Purging Its Secrets?

Enteric Campylobacter: Purging Its Secrets?

Epidemiology ofCampylobacter jejuniIsolated from Patients with Guillain-Barré and Fisher Syndromes in Japan

Association of Campylobacter upsaliensis with Persistent Bloody Diarrhea

Contact Info

Product

Resources

About