Campylobacter pylori infection in children

Eastham, E J; Elliott, T. S. J.; Berkeley, D; Jones, D. M.

doi:10.1016/s0163-4453(88)96205-6

Cited by 29 publications

(31 citation statements)

References 5 publications

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“…Because Eastham et al . first reported an association between H. pylori and NG in children in 1988, NG has been considered to be restricted to children infected with H. pylori according to several reports .…”

Section: Discussionmentioning

confidence: 99%

“…Nodular gastritis (NG) is defined as antral gastritis with endoscopic findings usually characterized by a miliary pattern resembling “goose flesh.” Histopathological features from the granular nodules on the mucosa of NG include lymphoid follicles and hypertrophy of the lacunar epithelium . There is a close association between Helicobacter pylori ( H. pylori ) infection, active chronic gastritis in childhood, young women, and NG.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and characteristics of nodular gastritis in Japanese elderly

Kitamura

Yasuda²,

Muguruma

et al. 2013

J of Gastro and Hepatol

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence and characteristics of nodular gastritis in Japanese elderly

Kitamura

Yasuda²,

Muguruma

et al. 2013

J of Gastro and Hepatol

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“…Drumm and co-workers performed both retrospective (23) and prospective (24) stud-ies and found evidence of C. pylori in the antrum of patients with active gastritis, but not in patients with normal gastric mucosa or in patients with gastritis resulting from other known conditions. Eastham et al (25) found the organism in association with antral gastritis. The patients had circulating antibody to the bacterium, and treatment eradicated the organism and resulted in resolution of inflammation and symptoms.…”

Section: Gastritismentioning

confidence: 99%

Campylobacter pylori and gastroduodenal disease

Buck

1990

Clin Microbiol Rev

139

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Campylobacter pylori is a newly described, spiral-shaped, gram-negative bacillus that is oxidase positive, catalase positive, and urease positive and grows slowly in culture. Although observed in human tissue at the beginning of the century, it was not cultured until 1982. Because there are significant morphological and genetic differences between this organism and other species of Campylobacter, it will probably be reclassified in a new genus. Current information indicates that the organism primarily resides in the stomach tissue of humans and nonhuman primates and may occasionally spread to the esophagus or other parts of the alimentary tract under appropriate conditions. Significant evidence has accumulated in the last several years to show that it causes gastritis, and there is mounting evidence that it may participate in the development of duodenal ulcers. It may also be associated with gastric ulcers and nonulcer dyspepsia. It can be detected in patients by culture of biopsy specimens or histological staining of biopsy tissue. Indirect evidence for the presence of the organism can be obtained by detection of urease in a tissue biopsy specimen, by urea breath tests, or by detection of specific antibody. It may not be necessary to implement these procedures for routine use, however, until the role of the organism can be defined better. Ultimately, the discovery of this organism may lead to radical changes in the diagnosis and treatment of gastric disease.

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“…Prospective studies on children with non-specific abdominal pain suggest that antral gastritis and H pylori are found more commonly than would be expected in assymptomatic children of a similar age.8 83 There is some evidence that treatment will improve symptoms, but numbers again are small. 84 Children represent a particularly important population group who may help to clarify our understanding of H pylori infection. Their upper gastrointestinal tract is subjected to less self poisoning, with low rates of non-steroidal anti-inflammatory drug usage, little smoking, and only modest consumption of alcohol in comparison to adults.…”

Section: Gastric Ulcermentioning

confidence: 99%