Can Frequency-doubling Technology and Short-wavelength Automated Perimetries Detect Visual Field Defects Before Standard Automated Perimetry in Patients With Preperimetric Glaucoma?

Abstract

FDT and SWAP detect functional losses in cases of suspected glaucoma before glaucomatous losses detected by SAP.

Scanning laser polarimetry: logistic regression analysis for perimetric glaucoma diagnosis

“…Numerous studies [17][18][19][20][21][22][23][24] have reported the sensitivity and specificity of different versions of SLP for discriminating between healthy and glaucomatous eyes. Very few studies [25][26][27][28] however have tried to combine SLP variables to obtain an LDF to increase the diagnostic accuracy of isolated GDx-VCC-provided parameters.…”

“…A low value represents low modulation and is associated with RNFL loss. Unfortunately, the normalized inferior area is not included in the standard printout, even though several studies 20,23 have reported that this parameter can provide a good ability to detect changes of the RNFL.…”

“…On the other hand, in some cases SAP may detect glaucomatous visual field defects when the disease is clinically advanced. 23,[34][35][36][37] Thus, the glaucoma group might have had a more advanced stage of the disease 38 than that represented by the perimetric indices, leading to a better diagnostic ability of the GDx-VCC.…”

Functional Testing in Glaucoma Diagnosis

“…In fact, SWAP may detect functional deficits up to 5 years earlier than SAP in some patients [32,33]. In addition, in many cases, defects detected by SWAP correlate with early structural glaucomatous damage [34,35]. Moreover, some longitudinal studies suggest that SWAP may provide a better predictor of photographically-determined structural change than SAP [36, 37 • , 38].…”

Current Concepts in the Diagnosis of Primary Open Angle Glaucoma

“…Other modes of testing which involve motion detection, frequency-doubling technology (FDT) and short-wavelength automated parameterizes (SWAP) detect visual field defects before standard automated perimetry in patients with preperimetric glaucoma and may enable earlier diagnosis. 29,31 In a report by the American Academy of Ophthalmology, 32 the four automated perimetry techniques that were assessed were short wavelength automated perimetry (SWAP), frequency doubling technology perimetry (FDT), high-pass resolution perimetry (HPRP), and motion automated perimetry (MAP). The algorithms described were the Swedish interactive threshold algorithm (SITA) and SITA fast.…”