Capillary glucose determination in the screening of gestational diabetes

Meriggi, E; Trossarelli, Gian Franco; Carta, Q; Menato, Guido; Porta, Maria Angela; Bordon, R; Gagliardi, L

doi:10.1016/s0168-8227(88)80079-2

Cited by 7 publications

(8 citation statements)

References 17 publications

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“…Although capillary blood testing is less accurate than venous, the difference in accuracy that we observed in capillary vs plasma GCT (area under the ROC value differences of ~ 0.03) was similar to that in the SIGT study [7], and smaller than has been observed with capillary vs plasma fasting glucose [20]; however, while area under the ROC values were similar, mean glucose levels were consistently higher in capillary vs plasma GCT tests; screening with capillary GCT would require the use of higher threshold values to achieve similar sensitivity and specificity, as has been suggested previously for gestational diabetes screening [21]. While capillary testing is more convenient and can provide immediate results to patients, capillary GCT thresholds might differ with alternative glucose meter systems, and improvements in accuracy and standardization of capillary meters may be needed before widespread use of a capillary screening test could be recommended.…”

Section: Discussionsupporting

confidence: 78%

Glucose challenge test screening for prediabetes and early diabetes

et al. 2016

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Aims To test the hypothesis that a 50-g oral glucose challenge test with 1-h glucose measurement would have superior performance compared with other opportunistic screening methods. Methods In this prospective study in a Veterans Health Administration primary care clinic, the following test performances, measured by area under receiver-operating characteristic curves were compared: oral glucose challenge test; random glucose; and HbA1c level, using an oral glucose tolerance test as the ‘gold standard’. Results The study population comprised 1535 people (mean age 56 years, BMI 30.3 kg/m2, 94% men, 74% black). By oral glucose tolerance test criteria, diabetes was present in 10% and high-risk prediabetes was present in 22% of the cohort. The plasma glucose challenge test provided area under receiver-operating characteristic curves of 0.85 (95% CI 0.78–0.91) to detect diabetes and 0.76 (95% CI 0.72–0.80) to detect high-risk dysglycaemia (diabetes or high-risk prediabetes), while area under receiver-operating characteristic curves for the capillary glucose challenge test were 0.82 (95% CI 0.75–0.89) and 0.73 (95% CI 0.69–0.77) for diabetes and high-risk dysglycaemia, respectively. Random glucose performed less well [plasma: 0.76 (95% CI 0.69–0.82) and 0.66 (95% CI 0.62–0.71), respectively; capillary: 0.72 (95% CI 0.65–0.80) and 0.64 (95% CI 0.59–0.68), respectively] and HbA1c performed even less well [0.67 (95% CI 0.57–0.76) and 0.63 (95% CI 0.58–0.68), respectively]. The cost of identifying one case of high-risk dysglycaemia with a plasma glucose challenge test would be $42 from a Veterans Affairs perspective, and $55 from a US Medicare perspective. Conclusions Glucose challenge test screening, followed, if abnormal, by an oral glucose tolerance test, would be convenient and more accurate than other opportunistic tests. Use of glucose challenge test screening could improve management by permitting earlier therapy.

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Section: Discussionsupporting

confidence: 78%

Glucose challenge test screening for prediabetes and early diabetes

et al. 2016

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“…104 The most commonly cited levels for the GCT are 7.2 and 7.8 mmol/l. ROC analysis by Meriggi and coworkers 149 has suggested a 7.5 mmol/l threshold while Sermer and co-workers 31 found values of 7.9-8.3 mmol/l, depending on time since last meal.…”

Section: Discussionmentioning

confidence: 97%

“…Lavin 148 reported the same PPV at ≥ 8.3 mmol/l. A study in a high prevalence group (European and Asian, 6.6%) by Yalcin and Zorlu, 146 in which women with screens ≥ 7.2 mmol/l were given a GTT, reported sensitivities of 98% and 88%, specificities of 44% and 85%, and PPVs of 32% and 9%, using thresholds of ≥ 7.5 and ≥ 7.8 mmol/l, respectively.Meriggi and co-workers, 149 in a selected population, contrasted the GCT using different blood and plasma thresholds. The plasma levels were lower but yielded similar results.…”

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confidence: 99%

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Screening for gestational diabetes: a systematic review and economic evaluation

Scott

Loveman

McIntyre³

et al. 2002

Health Technol Assess

180

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“…It is postulated that rejuvenation or regeneration of beta cells of the pancreas may be taking place, which may increase utilization and metabolism of glucose in peripheral tissues, liver, and adipose tissues through enzymatic processes. [ 33 34 ]…”

Section: Discussionmentioning

confidence: 99%

Yoga: As an adjunct therapy to trim down the Ayurvedic drug requirement in non insulin-dependent diabetes mellitus

Sharma¹,

Amin²,

Prajapati³

2014

Ancient Sci Life

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Introduction:In spite of a large number of drugs showing anti-hyperglycemic activities, none of them have been successful in complete management of diabetes mellitus (DM). Yoga and Ayurveda are the two schools of thought in India, which have a history of curing diseases since thousands of years. Yogic techniques and Ayurvedic herbs have proven their anti-diabetic potential without inducing untoward effects. The present study combines Ayurvedic medication with Yoga techniques as a new approach toward healing DM.Aims and Objectives:To assess the effect of Yoga therapy in the management of non insulin-dependent DM (NIDDM) and to decrease the oral drug dose requirement of guḍūcī ghana Tablet.Materials and Methods:Thirty known NIDDM patients of both genders, who were on guḍūcī ghana (solidified aqueous extract of Tinospora cordifolia (Willd.) Miers.) tablets from past 2 months as Ayurvedic remedy for DM were selected. Along with guḍūcī ghana administration, the subjects were instructed to follow Yogic procedures including Āsanas, prāṇāyāma, and śuddhi kriyās. The study was conducted for 8 weeks, wherein fasting blood sugar (FBS) and postprandial blood sugar (PPBS) levels along with relief in sign and symptoms were assessed at every 2 weeks intervals, and according to relief in sign and symptoms, tapering of drug dosage was carried out. The obtained data were analyzed statistically by applying paired t-test.Results and Conclusion:The results obtained were promising as the relief in diabetic symptomatology was highly significant in terms of P value. 80.83% reduction in dose of guḍūcī ghana tablets and 7.85% and 8.78% fall in FBS and PPBS levels, respectively, after the complete course of treatment. The obtained P value showed highly significant results.

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Capillary glucose determination in the screening of gestational diabetes

Cited by 7 publications

References 17 publications

Glucose challenge test screening for prediabetes and early diabetes

Glucose challenge test screening for prediabetes and early diabetes

Screening for gestational diabetes: a systematic review and economic evaluation

Yoga: As an adjunct therapy to trim down the Ayurvedic drug requirement in non insulin-dependent diabetes mellitus

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