Residues from beer production and macauba oil extraction are promising due to their composition of essential nutrients, fibers, and bioactive molecules. In this study, we analyzed the physical, rheological, and chemical properties of three kinds of flourspure macauba pulp cake flour (MC), pure brewer's spent grain flour (PM), and mixed flour (MS) composed of 80% (w/w) macauba flour and 20% (w/w) beer spent grainand apply them in the formulation of cookies. The flours presented high nutritional value. The incorporation of MC, MS, and PM flours influenced the quality of the cookies. MC was the one that most affected the characteristics of the cookies, meanwhile PM cookies showed characteristics closer to the standard cookie. Finally, MC, MS, and PM flours can be used in food formulations because of their potential to improve the nutritional quality of the product.