Carcinoma involving the gallbladder in elderly patients presenting with acute cholecystitis

Gallbladder cancer presenting with acute cholecystitis: a population-based study

“…However, the incidence of carcinoma of the gallbladder among patients presenting with acute cholecystitis has not been well studied. The present population-based study showed that the incidence of acute cholecystitis with cancer of the gallbladder (2.3%) was higher than the incidence with symptomatic gallstone diseases, but not to the extent of the 8.8% documented previously in a report from a single institution [7].…”

“…Although one report stated that 16% of patients with carcinoma of the gallbladder presented with symptoms of acute cholecystitis [8], the true incidence of gallbladder cancer among patients with acute cholecystitis is still largely unknown. In a recent small-scale study of 80 patients >60 years old presenting with acute cholecystitis at one institution, seven patients (8.8%) were diagnosed with gallbladder cancer [7]. This high incidence is especially alarming when LC is contemplated for acute cholecystitis.…”

“…In several large series of LC, its incidence was <1%. However, there are limited reports in the literature addressing the incidence or outcome of patients with gallbladder cancer presenting with acute cholecystitis [2,7,11]. Although one report stated that 16% of patients with carcinoma of the gallbladder presented with symptoms of acute cholecystitis [8], the true incidence of gallbladder cancer among patients with acute cholecystitis is still largely unknown.…”

Biliary tract surgery

“…In addition, gallbladder cancer may be common in the elderly patient with acute cholecystitis. Seven of 80 (9%) elderly patients undergoing cholecystectomy for acute cholecystitis in a recent retrospective review had incidentally discovered gallbladder cancer [40].…”

Laparoscopic cholecystectomy for early gallbladder carcinoma: long-term outcome in comparison with conventional open cholecystectomy

“…Previous reports have indicated that a relationship exists between gallbladder carcinoma and acute cholecystitis [13]. However, previous investigations at the authorsÕ institute have shown that concurrent primary gallbladder carcinoma combined with acute cholecystitis usually presented in older patients, and that the survival of these patients was not influenced by acute cholecystitis [4].…”