Cardiac tamponade in multiple myeloma – A pictorial case review of FDG PET/CT findings

Chen, Tony; Taubman, Kim; Hao, Xiaoyan; Yap, Kelvin; Schlicht, Stephen

doi:10.1111/1754-9485.12992

Cited by 2 publications

(4 citation statements)

References 4 publications

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“…Contrast echocardiography may facilitate the classification of intracardiac tumors and thrombi [ 12 ]. Positron emission tomography (PET)/CT and magnetic resonance imaging (MRI) may be helpful for characterizing the involvement of intramedullary and extramedullary lesions associated with MM [ 1 ]. In our case, contrast echocardiography was not performed, and cardiac MRI was also not performed due to the in situ pacemaker.…”

Section: Discussionmentioning

confidence: 99%

“…Multiple myeloma (MM) is a malignant disease of plasma cells commonly associated with bone marrow plasmacytosis. The incidence of extramedullary lesions in MM is approximately 6–20% [ 1 , 2 ]. However, cardiac involvement associated with MM is a rare manifestation with an incidence of less than 1% [ 1 – 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of extramedullary lesions in MM is approximately 6–20% [ 1 , 2 ]. However, cardiac involvement associated with MM is a rare manifestation with an incidence of less than 1% [ 1 – 3 ]. Thus, the experience in the diagnosis and management of cardiac involvement in MM is limited.…”

Section: Introductionmentioning

confidence: 99%

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Extramedullary intracardiac multiple myeloma misdiagnosed as a thrombus: a case report

Peng

Wang

2021

BMC Surg

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Background Extramedullary intracardiac multiple myeloma (MM) is extremely rare. Patients with extramedullary intracardiac MM may suffer from a poor prognosis. Experience in the diagnosis and therapy of cardiac involvement in MM is limited. Herein, we describe a 67-year-old male with extramedullary intracardiac MM who was initially misdiagnosed with a thrombus. Case presentation A 67-year-old male was admitted for exertional dyspnea and fatigue. The patient was diagnosed with MM one year earlier and had complete remission after chemotherapy. He was implanted with a permanent pacemaker two months prior due to sick sinus syndrome. After this admission, transthoracic echocardiography (TTE) and computed tomography (CT) confirmed the existence of a large right atrial mass extending to the superior and inferior vena cava. We initially considered the right atrial mass as a thrombus and performed surgical treatment for the patient. The surgical intervention partially relieved the obstruction of the superior and inferior vena cava and improved hemodynamics. Postoperative pathological examination of the right atrial mass suggested malignant plasmacytoma associated with MM. After recovery from the surgery, the patient received one cycle of chemotherapy. A follow-up of seven months revealed that our patient was still alive with a good general condition. Conclusions Increasing the awareness of extramedullary intracardiac lesions in patients with MM is warranted. Our case confirmed that surgical intervention followed by adjuvant chemotherapy could improve the patient’s hemodynamics and achieve remission of cardiac symptoms.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Extramedullary intracardiac multiple myeloma misdiagnosed as a thrombus: a case report

Peng

Wang

2021

BMC Surg

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“…Multiple myeloma (MM) is an atypical plasma cell dyscrasia in the bone marrow (BM) which accounts for about 10% of all hematological malignancies (1). While extramedullary disease is reported at a ratio of 6-20% in MM, cardiac and pericardial involvement is rare (2). In the event of cardiac or pericardiac involvement, on the other hand, progression into cardiac tamponade takes place in 60% of the patients (3-4).…”

Section: Introductionmentioning

confidence: 99%

Perikard Tutulumu Olan Multiple Myelom Olgusu

Davutoglu

Teke

YAMAN

et al. 2022

Osmangazi̇ Journal of Medicine

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Multiple myeloma (MM) is an atypical plasma cell dyscrasia in the bone marrow (BM) which accounts for about 10% of all hematological malignancies. While extramedullary disease (EMD) is reported at a ratio of 6-20% in MM, cardiac and pericardial involvement is rare. In the event of cardiac or pericardiac involvement, on the other hand, progression into cardiac tamponade takes place in 60% of the patients. We will present a very rare case of recurrence with pericardial involvement after autologous stem cell transplantation

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Cardiac tamponade in multiple myeloma – A pictorial case review of FDG PET/CT findings

Cited by 2 publications

References 4 publications

Extramedullary intracardiac multiple myeloma misdiagnosed as a thrombus: a case report

Extramedullary intracardiac multiple myeloma misdiagnosed as a thrombus: a case report

Perikard Tutulumu Olan Multiple Myelom Olgusu

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