Cardiac Tumors: Clinical Presentation, Diagnosis, and Management

Poterucha, Timothy J.; Kochav, Jonathan; O’Connor, Daniel S.; Rosner, Gregg

doi:10.1007/s11864-019-0662-1

Cited by 153 publications

(206 citation statements)

References 46 publications

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“…Constitutional symptoms include fever, weight loss, infections and so on, which may be attributed to the release of cytokine interleukin-6 (IL-6). Obstructive symptoms are usually associated with the resistance that any chamber or valve orifice have against blood flow [ 8 ]. Obstructive and embolic symptoms are totally different between left-sided and right-sided cardiac myxoma.…”

Section: Discussionmentioning

confidence: 99%

Giant right ventricular myxoma presenting as right heart failure with systemic congestion: a rare case report

Chen

Yang

2021

BMC Surg

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Background Myxoma is an uncommon disease and its symptoms vary greatly depending on size, location and mobility. Right-sided myxoma, especially right ventricular myxoma, is much rarer, and the symptoms are alien and uncharacteristic. The lack of understandings poses challenges to prompt diagnosis and timely treatment. Case presentation A 44-year-old female patient was diagnosed with giant right ventricular tumor. Right heart failure and systemic congestion caused by right ventricular outflow tract obstruction were observed on this case. Surgery was performed to excise the mass which was measured at 9.5 * 5.0 cm and confirmed as myxoma pathologically. Conclusions Right-side myxoma is easy to be unnoticed due to its low incident rate and atypical symptoms. Delay in surgical intervention might cause unrecoverable complications. More comprehensive understanding of the symptoms is expected to help improving the diagnose and treat of right-sided myxoma.

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Section: Discussionmentioning

confidence: 99%

Giant right ventricular myxoma presenting as right heart failure with systemic congestion: a rare case report

Chen

Yang

2021

BMC Surg

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“…Primary cardiac tumors have been reported at an incidence of 0.00138 to 0.03% and 80% of them are benign tumors. 6) 7) Cardiac myxomas have been well known as the most frequent primary benign cardiac tumors in adults accounting for 50–85% of them. 2) 7) TTE is a widely available, noninvasive diagnostic method for initial evaluation of cardiac myxomas.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Clinical and Echocardiographic Characteristics between Cardiac Myxomas and Masses Mimicking Myxoma

Lee

Park

et al. 2020

Korean Circ J

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Background and Objectives Cardiac myxoma is the most frequent benign cardiac tumor that can result in cardiac and systemic symptoms. We investigated clinical and echocardiographic characteristics of patients with cardiac masses suggesting myxoma. Methods We investigated 265 consecutive patients with an echocardiographic diagnosis of cardiac myxomas in 4 teaching hospitals in Korea. Results The mean age was 61±16 years and 169 patients (63.8%) were female. The most frequent referral reason for echocardiography was an evaluation of cardiac symptoms (43.4%). Tumors were incidentally detected in 82 patients (30.9%). Left atrium (LA) was the most frequently involved site (84.5%) and 19 patients (7.2%) had non-atrial tumors. The mean tumor size was 38.7×26.0 mm (range, 4–96 mm). Of 186 patients (70.2%) who had pathological diagnosis, 174 (93.5%) were confirmed with myxoma, 8 (4.3%) with other tumors and 4 (2.2%) with thrombi. Compared to myxoma, smaller size (20.4×12.6 mm vs. 41.4×27.6 mm, p<0.01) and non-LA location (87.5% vs. 10.5%, p<0.001) were associated with non-myxoma tumors, and more frequent atrial fibrillation (AF, 75.0% vs. 7.0%, p<0.001) and larger LA diameter (55.0±14.6 mm vs. 41.3±7.7 mm, p=0.001) were related to thrombi. Conclusions Of 265 patients with an echocardiographic diagnosis with cardiac myxomas, 174 (65.7%) were surgically confirmed with myxomas. Compared with cardiac myxoma, other tumors were smaller and more frequently found in non-atrial sites. Thrombi were associated with AF and larger LA diameter.

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“…Cardiac lymphoma is a disease confined to the heart or pericardium showing on cMRI features that are isointense on T1-weighted and mildly hyperintense on T2-weighted images 2. Pericardial cysts are congenital lesions visualised on cMRI as structures without any first pass or LGE, low T1 and high T2 signal intensity imaging 3. The distinction of the secondary malignant cardiac tumours is clinical, with the patient presenting extracardiac symptoms.…”

Section: Answer: Bmentioning

confidence: 99%

A 63-year-old woman with multiple secondary tumours

Mureşan

Agoşton-Coldea

Dumitraşcu

2020

Heart

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Clinical introductionA 63-year-old woman recently diagnosed with lung metastasis, after routine chest radiography, was admitted to our hospital for unspecified symptoms, such as dyspnoea on minimal exertion and dry cough. Physical examination showed uncommon signs. The electrocardiogram showed sinus rhythm and incomplete left bundle branch block. Thoracic CT scan revealed bilateral lung and pleural metastases and pelvic CT showed a right femoral bone mass. Transthoracic echocardiography revealed a heterogeneous mass, lateral to the right ventricle, with pericardial effusion. Further, cardiac MRI (cMRI) was performed (figure 1A,B). Diagnosis was completed with an ultrasound-guided biopsy and histopathological examination (figure 1C,D).Figure 1(A,B) Cardiac MRI: asterisk is suggestive of fluid and the white arrow indicates fibrous encapsulation by LGE, (C) H&E stain:white arrow indicating a tumoral cell with atypical mitosis and (D) immunohistochemical staining for smooth muscle actin antibody.QuestionWhich of the following is the most likely diagnosis?Pericardial lymphoma.Pericardial leiomyosarcoma.Pericardial cyst.Secondary malignant cardiac tumour.Pericardial teratoma.

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Cardiac Tumors: Clinical Presentation, Diagnosis, and Management

Cited by 153 publications

References 46 publications

Giant right ventricular myxoma presenting as right heart failure with systemic congestion: a rare case report

Giant right ventricular myxoma presenting as right heart failure with systemic congestion: a rare case report

Comparison of Clinical and Echocardiographic Characteristics between Cardiac Myxomas and Masses Mimicking Myxoma

A 63-year-old woman with multiple secondary tumours

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