Cardiobacterium hominis Endocarditis With Cerebral Mycotic Aneurysm

Abstract

Cardiobacterium hominis, a recently recognized Gram-negative pathogen, was recovered in blood cultures from a 65-year-old man with indolent endocarditis of previously normal heart valves. Despite the low virulence of the organism, major cardiac damage required valvular replacement, and there were multiple cerebral emboli with development of a mycotic aneurysm. After bacteriological cure, he died of a ruptured aneurysm.

Aortic homograft endocarditis caused by Cardiobacterium hominis and complicated by agranulocytosis due to ceftriaxone

“…The most common physical findings are a cardiac murmur (94%), peripheral embolic lesions (51%) and splenomegaly (40%) 9. The fact that we did not find any septic emboli, described to occur in approximately 50% of C hominis endocarditis cases,10 might potentially be explained by the relatively early presentation compared to cases reported in the literature 12 28–31. The diagnosis is usually established by clinical and echocardiography findings and positive blood cultures.…”

Endocarditis with Ruptured Cerebral Aneurysm Caused by Cardiobacterium valvarum sp. nov

“…However, the lack of early recognition of C. valvarum attests to its rarity (more rare than C. hominis). Cerebral aneurysm occurs as a rare complication of bacterial endocarditis, and to our knowledge, there have been only four reported cases of cerebral aneurysm with C. hominis endocarditis (10,12,13,16). In one of the cases (13; J. Lynfield, personal communication), the eventual diagnosis of indolent on May 11, 2018 by guest http://jcm.asm.org/ endocarditis was initially unsuspected for the 47-year-old man who presented with headache and aphasia and had a 30-year history of aortic valvotomy due to CBAV.…”

Mitral valve replacement in a patient with infective endocarditis and aneurysm of the cerebral artery: A case report

“…They occur at secondary branches and bifurcations, usually in the lateral fissure near the trifurcation of the medial cerebral artery. When aneurysms are formed, the most likely mechanism is bacterially induced weakening (9).…”