Catalytic thiomethylation of carboxylic acid hydrazides

Efficient catalytic method for the synthesis of N-aryl-substituted 1,5,3-dithiazamacroheterocycles

“…According to X-ray diffraction data, the 13-membered heterocyclic moiety in compounds 9k,i has a chairetwist-chair conformation. The torsion angle O(1)eC(13)eC(12)eO (11) in compound 9k is 64.36 , whereas in structure 9i, a similar angle is 60.66 . In compound 9k, the torsion angles S(8)eC(9)eC(10)eO (11) and S(4)eC(3)eC(2)eO(1) are 67.24 and 70.04 , respectively, while in structure 9k this angles are 74.34 and 79.11 , respectively.…”

Samarium(III) nitrate-catalyzed one-pot synthesis of 42-membered N,S,O-containing cyclophanes

“…As a continuation of the research into catalytic synthesis of heterocyclic compounds [36][37][38][39][40][41][42][43][44] and to develop a selective route to 42-…”

The synthesis of N-substituted N,S-macroheterocycles derived from aromatic carboxylic acid hydrazides

“…[10][11][12][13][14] Butane-1,4-dithiol, pentane-1,5-dithiol and hexane-1,6-dithiols were selected as the substrates for this study.…”

“…The replacement of gaseous H 2 S by ethane-1,2-dithiol or propane-1,3-dithiol in the above reaction allowed derivatization of carboxylic hydrazides to afford N-substituted 1,5,3-dithiazepanes and N-substituted 1,5,3-dithiazocanes in the presence of Cu complex catalysts. [11] Experimental High resolution mass spectra of compounds 1b, 2b, 2c and 4 ("dried droplet method") were recorded on a spectrometer "MALDI-TOF Autoflex III" (Bruker, Germany), with α-cyano-4-hydroxycinnamic acid as a matrix. Compounds 1c, 2a, 3a-c were analyzed by electrospray ionization (ESI) mass spectrometry Synthesis of N,S-Macroheterocycles with N-Amide Substitutents from Aromatic Carboxylic Acid Hydrazides on a Shimadzu LCMS-2010 EV instrument of the Center of Collective Use "Chemistry" of the Institute of Organic Chemistry, Ufa Scientific Center of RAS; the temperature of the heating source was 200 °C, the temperature of the vaporizer was 250 °C; nitrogen that was produced by an NM18L ultra-high purity nitrogen generator was used as the nebulizing gas; the liquid flow rate was 0.05 mL·min -1 , the nebulizing gas flow rate was 1.5 mL·min…”