Cemento-ossifying fibroma of mandible: An unusual case report and review of literature

Abstract

The term ossifying fibroma (OF) has recently been included under fibro-osseous lesions. Cemento-OF (COF) is a benign neoplasm that arises from the periodontal membrane which contains multipotential cells that are capable of forming cementum, lamellar bone and fibrous tissue. These tumors occur in the third and fourth decades of life with a predilection for women. The mandible is more commonly involved than the maxilla. This lesion has caused considerable controversy regarding the use of terminology, origin and diagnostic criteria. This article describes an unusual case of COF presenting as unilocular lytic lesion of mandible in a 38-year-old male patient with review of literature.

Large cemento-ossifying fibroma of the mandible involving the infratemporal and parapharyngeal spaces

“…Mandibular lesions often lead to expansion of the bone cortices and downward displacement of the lower border. Involvement of the maxillary sinus is noted in 90% maxillary lesions [9]. In our report, the patient exhibited tooth displacement and significant cortical expansion.…”

“…Earlier classifications had categorized OF as an osteogenic lesion and COF as an odontogenic lesion. However, the World Health organization revisions of head and neck neoplasms included both OF and COF in osteogenic neoplasms [5,9].…”

Multiple fibro-osseous lesions of the jaws: A report of a rare case with a literature review

“…Three overlapping clinico-pathological entities are recognized: 1) conventional ossifying fibroma, 2) juvenile trabecular ossifying fibroma, and 3) juvenile psammomatoid ossifying fibroma. 8 9 Ossifying fibromas most frequently occur in female patients with an incidence peak in the third and fourth decades of life. Seventy percent of cases of ossifying fibroma involve the mandible, but a significant percentage (22%) is found in the molar region of the maxilla, in the ethmoidal and orbital regions, and rarely in the petrous bone.…”

An Immature Ten-year Long-standing Case of Ossifying Fibroma

“…Sweet et al, however, did report a recurrence rate of almost 25% for maxillary lesions, but some of these may have been examples of juvenile active ossifying fibromas, which are more aggressive than ossifying fibroma [ 15 - 16 ]. There is no evidence of malignant transformation in these cases [ 17 ].…”