Central serous chorioretinopathy following pigment epithelium detachment: fluorescein and indocyanine green angiography follow‐up

Gómez‐Ulla, Francisco; Vázquez, José Manuel; Rodríguez‐Cid, María José; Des, Julio; González, Francisco

doi:10.1034/j.1600-0420.2000.078002232.x

Cited by 12 publications

(7 citation statements)

References 7 publications

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“…Indeed, cases have been reported where such solitary RPE detachment converted spontaneously to monofocal classic CSC (Bandello et al. 2000; Gomez‐Ulla et al. 2000).…”

Section: Differential Diagnosismentioning

confidence: 99%

Central serous chorioretinopathy

Wang

Munch

Hasler

et al. 2008

Acta Ophthalmologica

587

521

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ABSTRACT.Central serous chorioretinopathy (CSC) is a disease of the retina characterized by serous detachment of the neurosensory retina secondary to one or more focal lesions of the retinal pigment epithelium (RPE). CSC occurs most frequently in mid-life and more often in men than in women. Major symptoms are blurred vision, usually in one eye only and perceived typically by the patient as a dark spot in the centre of the visual field with associated micropsia and metamorphopsia. Normal vision often recurs spontaneously within a few months. The condition can be precipitated by psychosocial stress and hypercortisolism. Ophthalmoscopic signs of CSC range from mono-or paucifocal RPE lesions with prominent elevation of the neurosensory retina by clear fluid -typical of cases of recent onset -to shallow detachments overlying large patches of irregularly depigmented RPE. The spectrum of lesions includes RPE detachments. Granular or fibrinous material may accumulate in the subretinal cavity. Serous detachment often resolves spontaneously. From first contact, counselling about the potential relation to stress and glucocorticoid medication is warranted. After 3 months without resolution of acute CSC or in chronic CSC, treatment should be considered. Resolution of detachment can usually be achieved in acute CSC by focal photocoagulation of leaking RPE lesions or, in chronic CSC, by photodynamic therapy. The effect of therapy on long-term visual outcome is insufficiently documented. Reattachment within 4 months of onset is considered a relevant therapeutic target because prolonged detachment is associated with photoreceptor atrophy. This suggests that the value of treatment depends upon proper selection of cases that will not resolve without therapy. Chronic CSC may be difficult to differentiate from occult choroidal neovascularization secondary to CSC. Patients with chronic CSC who receive glucocorticoid treatment for systemic disease can often be managed without having to discontinue this medication.

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“…Indeed, cases have been reported where such solitary RPE detachment converted spontaneously to monofocal classic CSC (Bandello et al. 2000; Gomez‐Ulla et al. 2000).…”

Section: Differential Diagnosismentioning

confidence: 99%

Central serous chorioretinopathy

Wang

Munch

Hasler

et al. 2008

Acta Ophthalmologica

587

521

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“…Serous PEDs are reported frequently in conjunction with central serous chorioretinopathy [15]. In addition, some originally serous PEDs have been shown to transform to typical CSC, which include other components as well.…”

Section: Discussionmentioning

confidence: 99%

“…These findings detail that idiopathic serous detachments of the retinal pigment epithelium may represent predisposing changes for the development of macular neurosensory retinal detachment. However, there is no study available indicating from which PEDs CSC may develop [15, 16]. …”

Section: Discussionmentioning

confidence: 99%

Isolated Multiple Pigment Epithelial Detachments with Unknown Cause

Haşhaş

Goktas

Ataş

2014

Case Reports in Ophthalmological Medicine

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“…Der Nachweis von Veränderungen sowohl bei den A-Wellen als auch das Beobachten einer Reduktion der B-WellenAmplitude im multifokalen ERG lassen sekundäre Auswirkungen auf die Photorezeptoren vermuten [5]. Die Beteiligung des RPE beschreiben auch Autoren [3], die die CSCR als mögliche Verlaufsvariante einer Pigmentepithelabhebung sehen.…”

Section: Ergebnisseunclassified

Die Pathogenese der zentralserösen Chorioretinopathie

et al. 2001

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Of the patients 47 (96%) showed hypofluorescent areas in the early pictures of the ICG angiography which changed to hyperfluorescence in the late phase pictures in 39 patients (80%). Of the asymptomatic paired eyes, 31 (63%) showed abnormalities in the ICG pictures. The amplitudes in mERG were reduced in the study eyes as well as in the paired eyes and only recovered slowly. Angiographic healing was seen in 44 (90%) patients during the follow-up time, while the reduction of mERG amplitudes recovered more slowly and did not reach normal levels. CSC is a bilateral disease of the central choroid with acute decompensation of the retinal pigment epithelium in one eye. This leads angiographically to a local hypofluorescence with subsequent hyperfluorescence caused by barrier breakdown. The functional recovery follows the morphological healing only slowly. The mERG seems to be an adequate measurement method.

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Central serous chorioretinopathy following pigment epithelium detachment: fluorescein and indocyanine green angiography follow‐up

Cited by 12 publications

References 7 publications

Central serous chorioretinopathy

Central serous chorioretinopathy

Isolated Multiple Pigment Epithelial Detachments with Unknown Cause

Die Pathogenese der zentralserösen Chorioretinopathie

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