Indoor emergency response plays a critically important role in disaster management for cities, which must consider the evacuation of people in a dynamic indoor environment. The spatial model is the foundation for the specific analysis of indoor emergency responses, such as evacuations. The current spatial model for evacuation has three primary pitfalls: (1) it primarily focuses on static spatial information, such as rooms, doors, and windows, and lacks dynamic information, such as events and sensors; (2) it mainly focuses on the horizontal space and the static scene and lacks a multi-story component that considers the different properties of stairs compared to planar areas; and (3) it places emphasis on the indoor navigation calculation with a 2D/3D network, which lacks individual properties that can support more complicated analysis, such as congestion and stagnation. In this paper, we propose a dynamic indoor field model with three typical characteristics.(1) It includes not only static information but also dynamic information, such as outdoor and indoor building geometry, sensors, fire spread, and personnel behavior. (2) It supports multi-story buildings from the macro level (building level and floor level) to the micro level (room level and individual level) based on horizontal and vertical indoor space. (3) It supports spatial calculations based on a three-dimensional space grid and can analyze potential congestion and stagnation during evacuation. We design a corresponding evacuation method that supports individual evacuation route finding and evacuation assessment. We perform a series of analyses of the applicability of the proposed model and the efficiency of the designed evacuation method based on multi-story evacuation studies. The simulation includes a total evacuation population exceeding 7000 individuals, and the analysis suggests that the new model and algorithm are effective in planning indoor emergency routes that avoid potential congestion or stagnation.