Changes in Cyanogenic Glycoside Content and ^|^beta;-Cyanoalanine Synthase Activity in Flesh and Seeds of Japanese Plum (Prunus salicina Lindl.) during Development

Mizutani, Fusao; Hirota, Ryuji; Amano, Shoji; Hino, Ayako; Kadoya, Kazuomi

doi:10.2503/jjshs.59.863

Cited by 10 publications

(10 citation statements)

References 14 publications

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“…This leads to a resurgence in studies of the β ‐CAS pathway and its role in metabolizing the cyanide released from cyanogenic glycosides (Mizutani et al . ; Seigler ) and for the synthesis of amino acids in germinating seeds (e.g. Hasegawa et al .…”

Section: Introductionmentioning

confidence: 99%

“…; Mizutani et al . ; Nambisan & Sundaresan ; Elias et al . ; Forslund & Jonsson ; Sánchez‐Pérez et al .…”

Section: Introductionunclassified

“…Following the initial identification of the β-CAS pathway, much of the ensuing research focused on cyanogenesis in plants, especially the production of cyanogenic glycosides. This leads to a resurgence in studies of the β-CAS pathway and its role in metabolizing the cyanide released from cyanogenic glycosides (Mizutani et al 1991;Seigler 1991) and for the synthesis of amino acids in germinating seeds (e.g. Hasegawa et al 1994;Hasegawa et al 1995a).…”

Section: Introductionmentioning

confidence: 99%

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The β‐cyanoalanine synthase pathway: beyond cyanide detoxification

Machingura

Salomon

Jez

et al. 2016

Plant Cell & Environment

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Production of cyanide through biological and environmental processes requires the detoxification of this metabolic poison. In the 1960s, discovery of the β-cyanoalanine synthase (β-CAS) pathway in cyanogenic plants provided the first insight on cyanide detoxification in nature. Fifty years of investigations firmly established the protective role of the β-CAS pathway in cyanogenic plants and its role in the removal of cyanide produced from ethylene synthesis in plants, but also revealed the importance of this pathway for plant growth and development and the integration of nitrogen and sulfur metabolism. This review describes the β-CAS pathway, its distribution across and within higher plants, and the diverse biological functions of the pathway in cyanide assimilation, plant growth and development, stress tolerance, regulation of cyanide and sulfide signalling, and nitrogen and sulfur metabolism. The collective roles of the β-CAS pathway highlight its potential evolutionary and ecological importance in plants.

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Section: Introductionmentioning

confidence: 99%

“…; Mizutani et al . ; Nambisan & Sundaresan ; Elias et al . ; Forslund & Jonsson ; Sánchez‐Pérez et al .…”

Section: Introductionunclassified

Section: Introductionmentioning

confidence: 99%

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The β‐cyanoalanine synthase pathway: beyond cyanide detoxification

Machingura

Salomon

Jez

et al. 2016

Plant Cell & Environment

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“…P. amygdalus (almond), and P. armeniaca (apricot) all contain amygdalin as the major cyanogenic constituent. It has been demonstrated for several of these species that the total cyanogenic potential per gram dry weight of whole fruit increases during development, while at the same time the relative composition of the cyanogens changes from 100 % prunasin in the early stages of seed development to nearly 100 % amygdalin in the seed of the ripe fruits (Ohtsubo and Ikeda, 1994;Mizutani et al, 1991;Frehner et al, 1990). The same kind of developmental changes, in both content and composition have been seen in other seeds, such as for example flaxseed.…”

Section: Terms Of Referencementioning

confidence: 99%

“…Ripe seeds of the commercially important fruits of Prunus persica (peach), P. domestica (plum), P. avium/cerasus (cherry), P. dulcis (P. amygdalus) (almond), and P. armeniaca (apricot) all contain amygdalin as the major cyanogenic constituent. As shown for several Prunus spp., the total cyanogenic potential per gram dry weight of whole fruit rises during the early development and the relative composition of cyanogens changes from 100 % prunasin in the beginning to nearly 100 % of amygdalin in the seed of the ripening process (Ohtsubo and Ikeda, 1994;Mizutani et al, 1991;Frehner et al, 1990).…”

Section: Prunus Species (Seeds)mentioning

confidence: 99%

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to cyanogenic compounds as undesirable substances in animal feed

2007

EFSA Journal

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SUMMARYHydrogen cyanide (HCN) is formed following the enzymatic hydrolysis of cyanogenic glycosides, which are produced as secondary metabolites by various plant species. In the intact plant these cyanogenic compounds are stored separated from hydrolytic enzymes. Crushing of plant materials either by technical processes or by chewing by animals obliterates this separation and initiates the enzymatic hydrolysis of cyanogenic compounds, resulting ultimately in the formation of HCN. Hydrolysis to release HCN can also be accomplished by microorganisms in the digestive tract.

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Freeze‐induced cyanide toxicity does not maintain the cyanogenesis polymorphism in white clover (Trifolium repens)

Kooyers

Bakken

Ungerer

et al. 2018

American J of Botany

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These results suggest that freezing-induced HCN toxicity is unlikely to be responsible for the maintenance of the cyanogenesis polymorphism in white clover. However, energetic trade-offs associated with costs of producing the cyanogenic precursors may confer a fitness benefit to acyanogenic plants under stressful climatic conditions. The lack of evidence for HCN toxicity suggests that cyanogenic clover uses physiological mechanisms mediated by β-cyanoalanine synthase and alternative oxidase to maintain cellular function in the presence of HCN.

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Changes in Cyanogenic Glycoside Content and ^|^beta;-Cyanoalanine Synthase Activity in Flesh and Seeds of Japanese Plum (Prunus salicina Lindl.) during Development

Cited by 10 publications

References 14 publications

The β‐cyanoalanine synthase pathway: beyond cyanide detoxification

The β‐cyanoalanine synthase pathway: beyond cyanide detoxification

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to cyanogenic compounds as undesirable substances in animal feed

Freeze‐induced cyanide toxicity does not maintain the cyanogenesis polymorphism in white clover (Trifolium repens)

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