“…However, since these symptoms are usually more tolerable than other symptoms cause by massive, irregular bleeding or severe pain, it is not surprising that a generic questionnaire cannot necessarily reflect such an improvement. As the WHOQOL-BREF was demonstrated to effectively show a significant difference between a normal population and patients with human immunodeficiency virus infection [26], epilepsy [27], end-stage renal disease [28], and low back pain [29] in the Taiwanese, it may also detect a difference between patients with uterine weights greater than 300 g vs. uterine weights lesser than 300 g, albeit in the opposite direction ( Figure 2). The finding could explain why our study participants with a small uterus had more severe symptoms that caused them to seek an operation.…”